- Ann Arbor MI, US Emily Holloway - Ann Arbor MI, US Jason Spence - Ann Arbor MI, US
International Classification:
C12N 5/071 G01N 33/50
Abstract:
The invention disclosed herein generally relates to methods and systems for improving physiological growth of cultured tissues. In particular, the invention disclosed herein relates to methods and systems for promoting maintenance of cultured intestinal organoids (e.g., derived from pluripotent stem cells or from primary sources such as biopsy tissue).
Compositions And Methods For Obtaining Vascularized Human Intestinal Organoid Tissue, And Related Uses Thereof
- Ann Arbor MI, US Jason Spence - Ann Arbor MI, US
International Classification:
C12N 5/071
Abstract:
The invention disclosed herein generally relates to methods and systems for converting stem cells into specific tissue(s) or organ(s) through directed differentiation. In particular, the invention disclosed herein relates to methods and systems for promoting vascularized human intestinal organoid tissue having an intestine-specific EC transcriptional signature from hindgut spheroid tissue produced in vitro from the described methods.
Synthetic Hydrogel Carriers For Cellular Structures, Generation Of Organoids, And Treatment Of Tissue Injury
"In real-world operations, an aerodynamic tractor doesn't guarantee optimal aerodynamics for the tractor-trailer combination," said Jason Spence, Volvo Trucks product marketing manager. "Through our holistic design approach, we've made further enhancements at key exterior and interior locations of o