Merck& Co. since Apr 2010
Pipeline Leader Biologics, Pipeline Leader Neuroscience and Opthalmology, Project Management
Merck&Co. Aug 1998 - Feb 2001
Research associate -Bioprocess R&D
Education:
Penn State University
MBA, business
Penn State University
MS, Chemical Engineering
Skills:
Biotechnology Drug Development Clinical Development Vaccines Pharmaceutical Industry Diabetes Clinical Trials R&D Biochemistry Cross Functional Team Leadership Neuroscience Biologics Life Sciences Drug Discovery Fda Glp Antibodies
Michel M. Chartrain - Westfield NJ Jayanthi Reddy - Scotch Plains NJ David M. Tschaen - Holmdel NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 722 C12P 4100
US Classification:
435156
Abstract:
Stereospecific (S)-6-bromo-2-tetraol is a key intermediate in the chemical synthesis of the chiral drug candidate, MK499, a ventricular arrythmias suppressant. The yeast strain Trichosporon capitatum (MY 1890) was employed for the bioconversion of 6-bromo-2-tetralone to the corresponding alcohol.
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