Jean J Chang

US Patent:

7612170, Nov 3, 2009

Filed:

Jan 13, 2006

Appl. No.:

11/332037

Inventors:

Juha Punnonen - Belmont CA, US
Alexandra L. L. Lazetic - San Jose CA, US
Steven R. Leong - Berkeley CA, US
Jean Chia-Chun Chang - Los Gatos CA, US

Assignee:

Maxygen, Inc. - Redwood City CA

International Classification:

C07K 14/705
C07K 16/46
A61K 38/16

US Classification:

530350, 5303873, 514 12, 4241341

Abstract:

The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability of the polypeptides to preferentially bind a CD28 or CTLA-4 receptor at a level greater or less than the ability of human B7-1 to bind CD28 or CTLA-4, or to induce or inhibit altered level of T cell proliferation response greater compared to that generated by human B7-1. The polypeptides and polynucleotides of the invention are useful in therapeutic and prophylactic treatment methods, gene therapy applications, and vaccines.

US Patent:

20050154189, Jul 14, 2005

Filed:

Jun 21, 2002

Appl. No.:

10/479901

Inventors:

Juha Punnonen - Belmont CA, US
Alexandra Lazetic - San Jose CA, US
Steven Leong - Berkeley CA, US
Jean Chang - Los Gatos CA, US
Doris Apt - Sunnyvale CA, US
Claes Gustafsson - Belmont CA, US

International Classification:

C07K014/74
C07K016/28

US Classification:

530350000, 530388220

Abstract:

The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability of the polypeptides to preferentially bind a human CD28 or CTLA-4 receptor at a level greater or less than the ability of human B7-1 to bind human CD28 or CTLA-4, or to induce or inhibit altered level of T cell proliferation response greater compared to that generated by human B7-1. The polypeptides and polynucleotides of the invention are useful in therapeutic and prophylactic treatment methods, gene therapy applications, and vaccines.

US Patent:

20230052973, Feb 16, 2023

Filed:

Oct 28, 2022

Appl. No.:

17/976634

Inventors:

- San Francisco CA, US
Jean Chang - San Francisco CA, US
Leah Bryson - Oakland CA, US

International Classification:

A41D 31/06
B32B 7/027
B32B 27/12

Abstract:

A thermally adaptive material configured to assume a lofted configuration and flat configuration in response to different temperatures. The thermally adaptive material includes an adaptive first textile layer with one or more sections of a first material that has a first thermal expansion coefficient and one or more sections of a second material disposed adjacent to the one or more sections of the first material, the one or more sections of the second material having a second thermal expansion coefficient that is different from the first thermal expansion coefficient. The thermally adaptive material also includes a second textile layer disposed opposing the adaptive first textile layer; a plurality of engaging portions between the first textile layer and second textile layer; and one or more cavities defined by the first and second layers that are generated while the adaptive textile is at least in a lofted configuration.

US Patent:

20210025091, Jan 28, 2021

Filed:

Sep 29, 2020

Appl. No.:

17/036210

Inventors:

- San Francisco CA, US
Saul Griffith - San Francisco CA, US
Shara Maikranz - San Francisco CA, US
Jean Chang - San Francisco CA, US
Pete Lynn - Oakland CA, US

International Classification:

D04B 21/00
B32B 27/02
B32B 5/02
B32B 7/08
B32B 5/12
B32B 15/04
B32B 15/02
B32B 5/04
B32B 15/14
B32B 5/26
B32B 5/06
B32B 15/08
B32B 3/26
B32B 7/12
B32B 27/08
B32B 7/05
A41D 31/06

Abstract:

An adaptive textile that includes a plurality of a first fiber having a first expansion coefficient and a plurality of a second fiber having a second expansion coefficient. There is a difference between the expansion coefficient of the first fiber and the expansion coefficient of the second fiber; at least one of the first or second fibers is a twisted coil actuator; and linear displacement of the twisted coil actuator causes the adaptive textile to bend.

US Patent:

20200399795, Dec 24, 2020

Filed:

Sep 1, 2020

Appl. No.:

17/009099

Inventors:

- San Francisco CA, US
Jean Chang - San Francisco CA, US
Shara Maikranz - Portland OR, US

International Classification:

D02G 1/20
D02G 1/02
D06M 11/05
D02G 3/38
D02G 3/02
D06M 11/84
D02G 3/36
D02G 3/32
D02G 3/40

Abstract:

A method of generating a coiled actuator fiber that includes twisting a fiber to generate a twisted fiber; wrapping the twisted fiber around a core yarn or fiber to generate a coil in the twisted fiber, which generates a coiled twisted fiber; setting the coiled twisted fiber by heat or chemical treatment; and removing at least a portion of the core yarn or fiber to generate a coiled actuator fiber.

US Patent:

20190269188, Sep 5, 2019

Filed:

Mar 5, 2019

Appl. No.:

16/292965

Inventors:

- San Francisco CA, US
Jean Chang - San Francisco CA, US
Leah Bryson - Oakland CA, US

International Classification:

A41D 31/06
B32B 7/027
B32B 27/12

Abstract:

A thermally adaptive material configured to assume a lofted configuration and flat configuration in response to different temperatures. The thermally adaptive material includes an adaptive first textile layer with one or more sections of a first material that has a first thermal expansion coefficient and one or more sections of a second material disposed adjacent to the one or more sections of the first material, the one or more sections of the second material having a second thermal expansion coefficient that is different from the first thermal expansion coefficient. The thermally adaptive material also includes a second textile layer disposed opposing the adaptive first textile layer; a plurality of engaging portions between the first textile layer and second textile layer; and one or more cavities defined by the first and second layers that are generated while the adaptive textile is at least in a lofted configuration.

US Patent:

20180291535, Oct 11, 2018

Filed:

Apr 10, 2018

Appl. No.:

15/949881

Inventors:

- San Francisco CA, US
Jean Chang - San Francisco CA, US
Shara Maikranz - Portland OR, US

International Classification:

D02G 1/20
D02G 1/02
D06M 11/05
D02G 3/38
D02G 3/02

Abstract:

A system and method of generating a coiled actuator fiber. The method includes twisting a fiber to generate a twisted fiber, wrapping the twisted fiber around a core to generate a coil in the twisted fiber; and removing at least a portion of the core to generate a coiled actuator fiber. In some aspects that fiber can be a yarn with one or more fibers or a fiber comprising a single elongated element. In some aspects, a portion of the core includes a removable sacrificial portion. The removable sacrificial portion can be dissolvable in a solvent or physically removable. In some aspects, the core further includes a non-dissolvable portion that is not dissolvable and generating a coiled actuator can include removing the sacrificial portion by treating a twisted fiber on the core to remove the sacrificial portion and leaving the non-dissolvable portion.

US Patent:

20160340814, Nov 24, 2016

Filed:

May 20, 2016

Appl. No.:

15/160439

Inventors:

- San Francisco CA, US
Saul Griffith - San Francisco CA, US
Shara Maikranz - San Francisco CA, US
Jean Chang - San Francisco CA, US
Pete Lynn - Oakland CA, US

International Classification:

D04H 1/42
D04B 21/00

Abstract:

An adaptive sheet that includes a first layer defining a first length, the first layer configured to assume a base configuration in response to a first environmental condition and assume a lofted configuration in response to a second environmental condition with the first layer being curled along the first length compared the base configuration. The first fabric layer includes a first material defining a second length and having a first expansion coefficient, and wherein the first material is configured to increasingly change length along the second length in response to the second environmental condition, and a second material defining a third length and having a second expansion coefficient that is different than the first expansion coefficient.