Jeffrey S Graves

US Patent:

59164255, Jun 29, 1999

Filed:

May 16, 1996

Appl. No.:

8/648675

Inventors:

Matthew J. Leader - Laguna Niguel CA
Jeffrey Graves - San Clemente CA

Assignee:

Sendx Medical, Inc. - Carlsbad CA

International Classification:

G01N 27333

US Classification:

204416

Abstract:

The present invention is an electronic wiring substrate for sensors formed over a subminiature through hole. Because of the small diameter of the through hole, the material that fills the through hole and the through hole itself have an essentially negligible effect on the sensor. Only a small amount of conductive material which fills each through hole is in contact with each associated electrode. Therefore, the purity of the electrode is not significantly altered by the conductive material coupled to the electrode. A relatively large number of sensors can be formed on the surface of the substrate within a relatively small fluid flowcell. Thus, more information can be attained using less blood. The substrate is essentially impervious to aqueous electrolytes and blood over long periods of storage in potentially corrosive environments. Since the substrate does not break down or become unstable when exposed over time to such reactive environments, the isolation that is provided by the substrate remains very high between each sensor and each other sensor, between each sensor and each conduction path, and between each conduction path and each other conduction path.

US Patent:

58442006, Dec 1, 1998

Filed:

May 16, 1996

Appl. No.:

8/648694

Inventors:

Matthew J. Leader - Laguna Niguel CA
Jeffrey Graves - San Clemente CA
John M. Moorman - Carlsbad CA

Assignee:

SenDex Medical, Inc. - Carlsbad CA

International Classification:

B23K 2600

US Classification:

21912171

Abstract:

The present invention is a method for drilling a subminiature through hole through a substrate. The through holes of the present invention are preferably drilled through an alumina substrate which is essentially impervious to aqueous electrolytes and blood over long periods of storage in potentially reactive environments. The holes are drilled by directing a sealed type CO. sub. 2 laser at a predetermined position located on the substrate, energizing the laser at a power of approximately 75 to 225 watts, such that the laser beam focuses on the substrate at the predetermined position, and treating the substrate after the laser has drilled the hole.

US Patent:

60224630, Feb 8, 2000

Filed:

May 16, 1996

Appl. No.:

8/649009

Inventors:

Matthew J. Leader - Laguna Niguel CA
Jeffrey Graves - San Clemente CA

Assignee:

SenDx Medical, Inc. - Carlsbad CA

International Classification:

G01N 27333
G01N 27404

US Classification:

204416

Abstract:

The present invention is a sensor having an electrode formed in electrical contact with a subminiature through hole. Because of the small diameter of the through hole, the material that fills the through hole and the through hole itself have an essentially negligible effect on the sensor. A relatively large number of sensors can be formed on the surface of the substrate within a relatively small fluid flowcell. Thus, more information can be attained using less analyte. The sensors of the present invention are preferably disposed on an alumina substrate which is essentially impervious to aqueous electrolytes and blood over long periods of storage in potentially corrosive environments. Since the substrate on which the sensors are deposited, and the encapsulants which insulate the conductive elements of the sensor do not break down or become unstable when exposed over time to such corrosive environments, the isolation that is provided remains very high between each sensor and each other sensor, between each sensor and each conduction path, and between each conduction path and each other conduction path. The superior isolation provides for a high level of accuracy in the sensor of the present invention.

US Patent:

53424980, Aug 30, 1994

Filed:

Jun 26, 1992

Appl. No.:

7/905254

Inventors:

Jeffrey A. Graves - San Juan Capistrano CA
Marshall L. Sherman - Cardiff CA
Matthew J. Leader - Laguna Niguel CA
Kee V. Sin - Lino Lakes MN

International Classification:

G01N 2726

US Classification:

204408

Abstract:

An improved electronic wiring board having a thermistor and at least one blood gas sensor supported, in close relation, one to the other, on one side of the board and a heater supported on the other side of the board to provide heat in response to temperature sensed by the thermistor, to at least the region where the thermistor and the blood gas sensor are positioned on the board to control the temperature of the region of the board within a narrow distribution of temperatures.

US Patent:

61465100, Nov 14, 2000

Filed:

May 16, 1996

Appl. No.:

8/648676

Inventors:

Matthew J. Leader - Laguna Niguel CA
Jeffrey Graves - San Clemente CA
Douglas R. Savage - Del Mar CA

Assignee:

SenDx Medical, Inc. - Carlsbad CA

International Classification:

G01N 27333

US Classification:

204416

Abstract:

The present invention is a sensor formed over a subminiature through hole. Because of the small diameter of the through hole, the material that fills the through hole and the through hole itself have an essentially negligible effect on the sensor. Only a small amount of conductive material which fills each through hole is in contact with each associated electrode. Therefore, the purity of the electrode is not significantly altered by the conductive material coupled to the electrode. A relatively large number of sensors can be formed on the surface of the substrate within a relatively small fluid flowcell. Thus, more information can be attained using less blood. The sensors of the present invention are preferably disposed on an alumina substrate which is essentially impervious to aqueous electrolytes and blood over long periods of storage in potentially corrosive environments. Since the substrate on which the sensors are deposited does not break down or become unstable when exposed over time to such corrosive environments, the isolation that is provided by the substrate remains very high between each sensor and each other sensor, between each sensor and each conduction path, and between each conduction path and each other conduction path. The superior isolation provided by the substrate provides for a high level of accuracy in the sensor of the present invention.

US Patent:

58584528, Jan 12, 1999

Filed:

Mar 12, 1997

Appl. No.:

8/816188

Inventors:

Matthew J. Leader - Laguna Niguel CA
Jeffrey Graves - San Clemente CA

Assignee:

Sendx Medical, Inc. - Carlsbad CA

International Classification:

G01N 27403

US Classification:

427 97

Abstract:

The present invention is an electronic wiring substrate for sensors formed over a subminiature through hole. Because of the small diameter of the through hole, the material that fills the through hole and the through hole itself have an essentially negligible effect on the sensor. Only a small amount of conductive material which fills each through hole is in contact with each associated electrode. Therefore, the purity of the electrode is not significantly altered by the conductive material coupled to the electrode. A relatively large number of sensors can be formed on the surface of the substrate within a relatively small fluid flowcell. Thus, more information can be attained using less blood. The substrate is essentially impervious to aqueous electrolytes and blood over long periods of storage in potentially corrosive environments. Since the substrate does not break down or become unstable when exposed over time to such reactive environments, the isolation that is provided by the substrate remains very high between each sensor and each other sensor, between each sensor and each conduction path, and between each conduction path and each other conduction path.