A method for treating mouth ulcers (canker sores/aphthous ulcers) with licorice extract oral patches to speed healing and relieve pain. If licorice extract is applied to a mouth ulcer using an adhesive oral patch that delivers the medication for at least 30 minutes and the patches are used for at least two or more hours per day, the method reduces the healing times from typically 10–14 days to typically 2 days. The licorice extract patches also quickly reduces canker sore pain and, if used before commencing a meal, reduces pain during the meal. A fully dissolving patch with licorice extract and collagen is disclosed.
A wireless electronic authentication device with an authenticating smart chip, a local radio communication circuit, an input circuit that receives user input, and a power supply, all housed in a portable housing. Preferably, the authentication device is a mobile telephone with an authenticating smart chip. The user enters a knowledge token, such as a password stated by voice or a personal identification number input at the keyboard, to indicate that he is both in possession of the authorization device and knows the critical information. The knowledge token may be entered in advance and merely confirmed by the user pressing a key on the keypad when a confirmation is requested. A method is provided for making use of the authentication device to perform authorizations. A similar method is disclosed for use in existing systems and then achieving a gradual transition from existing systems to the new authentication device.
Multi-Layer Patch Made On A Sheet And Enclosed In A Blister
A muco-adhesive patch for delivery of drugs into mucous membranes. On the muco-contact side, a water impermeable layer covers the center of the patch and less than half of the muco-contact side of the patch. Drugs may be added by mixing the drug with an adhesive material and placing a spot of the drug plus adhesive onto the exposed side of the water impermeable layer. A lenticular medical patch with a thin, tapered edge can be made with multiple layers by passing a single sheet such as a sheet of plastic through a production line in which each layer is applied in turn maintaining registration by reference to edges of the sheet or to marks on the sheet.
A soft, adherent, soluble oral patch for delivering topical medication in the mouth including a hydrophilic polymer that is liquid at human mouth temperatures. Preferably, the hydrophilic polymer gels to a solid at temperatures just below human mouth temperatures. The structure of the oral patch is formed with a porous network that remains solid at human mouth temperatures and slowly dissolves in saliva. In some embodiments, the network is elasto-plastic and in some cases it is hydrophilic. The hydrophilic polymer is located within pores of the network, along with a desired medication. The oral patch is formed by mixing and hydrating the ingredients, bringing them to a hot temperature just below boiling, and cooling them to form a gel. The hot mixture may be poured into molds and the mold may also serve as packaging for delivery. The packaging may comprise a germ barrier moisture passing film which allows the oral patch to dry out or become re-hydrated without growing mold.
Method For Manufacturing And Packaging Oral Patches With Rounded Edges
A method of manufacturing and packaging discs made of hydrophilic gums, such as adherent, soluble oral patches for delivering topical medication in the mouth. The hydrophilic gums are mixed with water and deposited as blobs onto base sheet material such as thermoplastic. The blobs on the sheets are then dried with air convection, causing the blobs to shrink in height, forming tapered discs with rounded edges. Before being deposited, the mixture may be heated to above an activation temperature that is below boiling, and then, after being deposited, the mixture is allowed to cool to form a gel. The base sheets serve as packaging and a lid sheet may be adhered to the base sheet, such as by heat sealing with a hot platten pressing both sheets against an anvil. The platen or the anvil (or both) has recesses that prevent the discs from being pressed during sealing. The sealed package is then cut to size, such as by die cutting.
A soluble/erodable troche for delivering collagen in the mouth for treatment of mouth lesions. The collagen may be gelatin from animal skins. The structure of the troche may be formed with a porous network that remains solid at human mouth temperatures and slowly dissolves/erodes in saliva. In some embodiments, the network is elasto-plastic and in some cases it is hydrophilic. The collagen is located within pores of the network. The troche may be formed by mixing and hydrating the ingredients, bringing them to above an activation temperature below boiling, and cooling them to form a gel. The hot mixture may be poured into molds, including a flat sheet, and the mold may also serve as packaging for delivery. The packaging may comprise a germ barrier moisture passing film which allows the troche to dry out or become re-hydrated without growing mold.
Water Soluble Anesthetic In An Oral Patch Of Hydrophilic Gums
An oral patch for treating toothaches and oral lesions, including mouth ulcers (canker sores/aphthous ulcers) with water soluble topical anesthetics such as dyclonine hydrochloride. In one embodiment, the patch is made by depositing blobs of wet mixture including anesthetic, muco-adhesive hydrocolloids such as collagen, and bingers onto flat sheets. The blobs on the sheets are then dried with air convection, causing the blobs to shrink in height, forming tapered discs with rounded edges. A coating is sprayed onto one side to prevent release of the anesthetic on that side. The base sheets serve as packaging and a lid sheet may be adhered to the base sheet, such as by heat sealing with a hot platen pressing both sheets against an anvil. The platen or the anvil (or both) has recesses that prevent the discs from being pressed during sealing. The sealed package is then cut to size, such as by die cutting.
Treating Mouth Sores Caused By Dental Braces With Blobs Of Hydrophilic Gums
A method for treating mouth sores caused by abrasion of orthodontic braces by placing oral patch or blob on the brace or sore to speed healing and relieve pain. The oral patch or blob is placed either on the portion of the brace that comes into contact with the sore or onto the sore directly. If certain medications are applied to a mouth sore using an oral patch or blob that restricts local flow of saliva and delivers the medication for at least 30 minutes and the patch or blobs are used for at least two or more hours per day, the method reduces the healing time for mouth sores from typical 10-14 days to 1-5 days. The method can be used with various antimicrobials, glucocorticoids or anthihistamines incorporated into the patch or blob that reduce inflammation or speed the healing of mouth sores caused by braces.
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Jeffrey Haley Principal
Distracted Driving Foundation Nonprofit Organization Management · School/Educational Services