This application is the expression and purification of a recombinant (3D7) MSP-1. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant MSP-1is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
In this application is described the expression and purification of a recombinant (FVO) MSP-1. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
In this application is the expression and purification of a recombinant (3D7) MSP-1. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant MSP-1is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
Expression, Purification And Uses Of A Liver Stage Antigen 1 Polypeptide
David E. Lanar - Takoma Park MD, US Collette J. Hillier - Concord, AU Jeffrey A. Lyon - Accident MD, US Evelina Angov - Bethesda MD, US Sanjai Kumar - Gaithersburg MD, US William Rogers - Jakata, ID Arnoldo Barbosa - Tolima, CO
Assignee:
The United States of America as represented by the Secretary of the Navy - Washington DC
International Classification:
C12N 15/00 A61K 39/015 C07K 14/445
US Classification:
435 691, 435 71, 4241911, 530350
Abstract:
In this application is described the expression and purification of a recombinant (3D7) LSA-NRC polypeptide. The method of the present invention produces a highly purified polypeptide which is useful as a vaccine and as a diagnostic reagent.
In this application is described the expression and purification of a recombinant (FVO) MSP-1. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
Isolation And Purification Of Merozoite Protein-142 Vaccine
In this application is the expression and purification of a recombinant (3D7) MSP-1. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant MSP-1is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
Evelina Angov - Bethesda MD, US Jeffrey A. Lyon - Silver Spring MD, US Christian Asare Darko - Silver Spring MD, US Joe D. Cohen - Brussels, BE
Assignee:
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:
A61K 39/015 A61K 38/00
US Classification:
4242681, 4241841
Abstract:
In this application is described the expression and purification of a recombinant (FVO) MSP-1. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
Expression, Purification And Uses Of A Plasmodium Falciparum Liver Stage Antigen 1 Polypeptide
David E. Lanar - Takoma Park MD, US Collette J. Hillier - Concord, AU Jeffrey A. Lyon - Accident MD, US Evelina Angov - Bethesda MD, US Sanjai Kumar - Gaithersburg MD, US William Rogers - FPO AP, US Arnoldo Barbosa - Tolima, CO
Assignee:
The United States of America as Represented by the Secretary of the Army - Washington DC
International Classification:
C12N 15/00 A61K 39/002
US Classification:
4353201, 4241911
Abstract:
In this application is described the expression and purification of a recombinant (3D7) LSA-NRC polypeptide. The method of the present invention produces a highly purified polypeptide which is useful as a vaccine and as a diagnostic reagent.