Jennifer C Bennett

US Patent:

6919351, Jul 19, 2005

Filed:

Oct 9, 2001

Appl. No.:

10/399083

Inventors:

Neville J. Anthony - Chalfont PA, US
Robert P. Gomez - Perkasie PA, US
Steven D. Young - Lansdale PA, US
Melissa S. Egbertson - Ambler PA, US
John S. Wai - Harleysville PA, US
Jennifer J. Bennett - Lansdale PA, US

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K031/4375
A61K031/502
A61K031/5415
C07D471/04
C07D417/12

US Classification:

514300, 5142252, 5142258, 514248, 514314, 546123, 546169, 544 42, 544 43, 544 46, 544236, 544237, 544184, 544279

Abstract:

Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.

US Patent:

6921759, Jul 26, 2005

Filed:

Oct 10, 2001

Appl. No.:

09/973853

Inventors:

Neville J. Anthony - Hatfield PA, US
Robert P. Gomez - Perkasie PA, US
Steven D. Young - Lansdale PA, US
Melissa Egbertson - Ambler PA, US
John S. Wai - Harleysville PA, US
Linghang Zhuang - Chalfont PA, US
Mark Embrey - North Wales PA, US
Jeffrey Y. Melamed - Doylestown PA, US
H. Marie Langford - Lansdale NJ, US
James P. Guare - Quakertown PA, US
Thorsten E. Fisher - Hatfield PA, US
Samson M. Jolly - Quakertown PA, US
Michelle S. Kuo - Gwynedd Valley PA, US
Debra S. Perlow - East Greenville PA, US
Jennifer J. Bennett - East Norriton PA, US
Timothy W. Funk - Ephrata PA, US

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61P031/00
A61K031/4375
C07D471/02

US Classification:

51421103, 51421108, 514218, 5142222, 5142225, 5142282, 5142345, 514249, 51425304, 514274, 514275, 514300, 514303, 540488, 540489, 540492, 540545, 544 3, 544 8, 544 586, 544127, 544310, 544331, 544349, 544362, 546118, 546 9, 546123

Abstract:

Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.

US Patent:

20040044207, Mar 4, 2004

Filed:

Aug 21, 2003

Appl. No.:

10/398988

Inventors:

Neville Anthony - Chalfont PA, US
Robert Gomez - Perkasie PA, US
Steven Young - Lansdale PA, US
Jennifer Bennett - Lansdale PA, US

International Classification:

C07D487/02

US Classification:

544/184000, 544/236000, 544/279000

Abstract:

Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating, or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.

US Patent:

20050176718, Aug 11, 2005

Filed:

Feb 11, 2005

Appl. No.:

11/056412

Inventors:

Neville Anthony - Hatfield PA, US
Robert Gomez - Perkasie PA, US
Steven Young - Lansdale PA, US
Melissa Egbertson - Ambler PA, US
John Wai - Harleysville PA, US
Linghang Zhuang - Chalfont PA, US
Mark Embrey - North Wales PA, US
Lekhanh Tran - Norristown PA, US
Jeffrey Melamed - Doylestown PA, US
H. Langford - Lansdale NJ, US
James Guare - Quakertown PA, US
Thorsten Fisher - Hatfield PA, US
Samson Jolly - Quakertown PA, US
Michelle Kuo - Gwynedd Valley PA, US
Debra Perlow - East Greenville PA, US
Jennifer Bennett - East Norriton PA, US
Timothy Funk - Ephrata PA, US

International Classification:

A61K031/498
A61K031/4745
C07D471/02
C07D487/02

US Classification:

514249000, 514300000, 544350000, 546123000

Abstract:

Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.