Jennifer C Chen

US Patent:

6553100, Apr 22, 2003

Filed:

Nov 7, 2000

Appl. No.:

09/707863

Inventors:

Jennifer H. Chen - Freehold NJ
Jerry Leger - Woodmere NY
Robert J. Sayko - Colts Neck NJ

Assignee:

ATT Corp. - New York NY

International Classification:

H04M 1100

US Classification:

379 37, 379 45

Abstract:

This invention provides for intelligent alerting systems that receive a notification, such as an incoming message or the like or indication thereof, or an indication of an abnormal condition, such as a device malfunction, a burglary attempt, or the like and alert end-users via one or more devices, including one or more enhanced performance reproduction devices such as an enhanced television or an enhanced radio. The systems include an intelligent processor that determines whether the one or more enhanced performance reproduction devices are reproducing a performance, and transmits an alert when a performance is being reproduced. The systems may also transmit an alert to other devices, such as pagers, telephones, personal computers, etc. When the notification indicates an abnormal condition, the systems may perform countermeasures, such as turning off a malfunctioning device, calling the police or the like.

US Patent:

7109307, Sep 19, 2006

Filed:

Nov 20, 2001

Appl. No.:

09/989350

Inventors:

Lih-Ling Lin - Concord MA, US
Jennifer Chen - Chestnut Hill MA, US
Andrea R. Schievella - Winchester MA, US
James Graham - Somerville MA, US

Assignee:

Genetics Institute, LLC - Cambridge MA

International Classification:

C07K 16/28

US Classification:

5303882, 4241391

Abstract:

Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.

US Patent:

20060188957, Aug 24, 2006

Filed:

Oct 7, 2005

Appl. No.:

11/245950

Inventors:

Lih-Ling Lin - Concord MA, US
Jennifer Chen - Chestnut Hill MA, US
Andrea Schievella - Winchester MA, US
James Graham - Somerville MA, US

International Classification:

C12P 21/06
C07H 21/04
C07K 14/715
C07K 16/30

US Classification:

435069100, 435320100, 435325000, 530350000, 530388220, 536023500

Abstract:

Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.

US Patent:

20090092613, Apr 9, 2009

Filed:

Feb 11, 2008

Appl. No.:

12/069735

Inventors:

Lih-Ling Lin - Concord MA, US
Jennifer Chen - Chestnut Hill MA, US
Andrea R. Schievella - Winchester MA, US
James Graham - Somerville MA, US

International Classification:

A61K 39/395
C12N 15/11
C12N 5/06
C12P 21/04
C07K 14/00
C12Q 1/68
A61K 38/16
C07K 16/18
G01N 33/566

US Classification:

4241391, 536 231, 435325, 435 691, 530350, 514 12, 5303879, 436501, 435 6

Abstract:

Novel TNF receptor death domain (“TNF-R1-DD”) ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.

US Patent:

20130347136, Dec 26, 2013

Filed:

Apr 11, 2013

Appl. No.:

13/861227

Inventors:

Jennifer Chen - Watertown MA, US
Oliver D. King - Cambridge MA, US

International Classification:

C12Q 1/68
A01K 67/027
C12N 5/077

US Classification:

800 9, 435 613, 435 61, 435325, 435 612, 435 71, 506 9

Abstract:

Compositions and methods for identifying new treatments for Facioscapulohumeral muscular dystrophy (FSHD), and uses thereof.

US Patent:

58495010, Dec 15, 1998

Filed:

Jun 19, 1995

Appl. No.:

8/494440

Inventors:

Lih-Ling Lin - Concord MA
Jennifer Chen - Chestnut Hill MA
Andrea R. Schievella - Winchester MA

Assignee:

Genetics Institute, Inc. - Cambridge MA

International Classification:

G01N 33566
C07K 1471
C07K 14475

US Classification:

435 71

Abstract:

Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.

US Patent:

58470999, Dec 8, 1998

Filed:

May 17, 1996

Appl. No.:

8/649341

Inventors:

Lih-Ling Lin - Concord MA
Jennifer Chen - Chestnut Hill MA

Assignee:

Genetics Institute, Inc. - Cambridge MA

International Classification:

C12N 1512
C12N 510
C12N 1563
C07K 1447

US Classification:

536 235

Abstract:

Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.

US Patent:

63229722, Nov 27, 2001

Filed:

Nov 2, 1998

Appl. No.:

9/185258

Inventors:

Lih-Ling Lin - Concord MA
Jennifer Chen - Chestnut Hill MA
Andrea R. Schievella - Winchester MA
James Graham - Somerville MA

Assignee:

Genetics Institute, Inc. - Cambridge MA

International Classification:

C12Q 168
G01N 3353

US Classification:

435 6

Abstract:

Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.