Jennifer M King

US Patent:

20070174019, Jul 26, 2007

Filed:

Oct 31, 2005

Appl. No.:

11/264259

Inventors:

Aditya Vailaya - Santa Clara CA, US
Allan Kuchinsky - San Francisco CA, US
Euan Ashley - Menlo Park CA, US
Jennifer King - Fremont CA, US
Rossella Ferrara - Imola, IT
Thomas Quertermous - Standford CA, US

International Classification:

G06F 17/18

US Classification:

702179000

Abstract:

Methods, systems and computer readable media for network-based identification of significant molecules, for which at least one biological network is provided to include significant molecules to be identified. A node in the network is identified. A member-specific sub-network containing nodes connected to the identified node is identified for L levels of nearest neighbors, wherein L is a positive integer, and a connectivity score is calculated for the molecule represented by the identified node based on significance scores of each node contained in the member-specific sub-network. These steps are repeated for other nodes in the network. Methods, systems and computer readable media for network-based identification of significant molecules, for which at least one biological network is provided to include significant molecules to be identified, a data set including data values characterizing molecules experimented on is provided, and an interesting list of molecules is provided as a subset of the molecules from the dataset, the interesting list including significance scores for the molecules in the list. Such identification includes identifying a node in the network; identifying a member-specific sub-network containing nodes connected to the identified node for L levels of nearest neighbors, wherein L is a positive integer; extracting the member-specific sub-network from the network; and repeating these steps for each of the other nodes in the network that corresponds to a molecule in the interesting list.

Address:

1470 Farnham Pt APT 101, Colorado Springs, CO 80904

VIN:

5GTDN13E778139918

Make:

HUMMER

Model:

H3

Year:

2007