Jennifer Nicole Lane

US Patent:

7244394, Jul 17, 2007

Filed:

Sep 3, 2003

Appl. No.:

10/654196

Inventors:

Fiona Patricia Carney - Atlanta GA, US
Jennifer Dawn Lane - Stone Mountain GA, US
Carol Ann Morris - Duluth GA, US

Assignee:

Novartis AG - Basel

International Classification:

G01N 21/00
G01N 31/22
C08F 16/06
C08F 116/06
C08F 216/06
A61M 35/00

US Classification:

422 58, 422 56, 422 57, 521141, 604294

Abstract:

The invention, in one aspect, provides a strip for tear collection. The strip has a first end and an opposite second end and preferably has substantially uniform cross-sections from the first end to the second end. The strip is made of a hydrogel material in substantially dry state. The strip is characterized by having a substantially uniform swelling along the hydrogel strip from the first end to the second end when fully wicked by a tear fluid and by having a correlation between the volume of tear uptake by said strip and the length of the wicked end portion of said strip. A strip of the invention is useful for assay of an analyte of interest in a tear fluid. The invention also provides a method and kits for assaying an analyte of interest (e. g. , lactoferrin, glucose, herpes simplex virus, hormones, etc. ).

US Patent:

7429462, Sep 30, 2008

Filed:

Feb 15, 2007

Appl. No.:

11/706809

Inventors:

Carol Ann Morris - Duluth GA, US
Fiona Patricia Carney - Atlanta GA, US
Jennifer Dawn Lane - Stone Mountain GA, US

Assignee:

Novartis AG - Basel

International Classification:

C12Q 1/54

US Classification:

435 14

Abstract:

The invention provides an in vivo screening assay and an in vitro screening assay for rapid screening of diabetes. A method of the invention includes determining a first glucose concentration in an ocular fluid of a patient; administering orally a load of carbohydrate to the patient; determining a second glucose concentration in an ocular fluid of the patient at a period of time of less than 50 minutes after orally administering of the load of carbohydrate; comparing the second glucose concentration with the first glucose concentration to determine if the patient is likely to be a diabetic. The method of the invention is performed by using a kit of the invention. The kit comprises: (1) a glucose-sensing ophthalmic device and instructions for using the glucose-sensing ophthalmic device to screen for diabetes; or (2) two or more tear-collecting devices, and a testing agent composition which specifically reacts with glucose to form a detectable signal. The glucose-sensing ophthalmic device comprises a testing agent composition which specifically and reversibly interacts with glucose to form a detectable optical signal which changes in a concentration-dependent manner.

US Patent:

8062607, Nov 22, 2011

Filed:

Jul 13, 2007

Appl. No.:

12/309347

Inventors:

Jennifer Dawn Lane - Stone Mountain GA, US
Stephen Raymond Perreault - Norcross GA, US
Elizabeth Hickson Beaullieu - Marietta GA, US

Assignee:

Novartis AG - Basel

International Classification:

A61L 9/00
B01J 19/00
G01D 11/26
A45C 11/04
B65D 73/00
B65D 83/04
B65D 35/00
A61K 7/075
A61K 9/00
G01N 31/00
A01K 43/00

US Classification:

422261, 422 1, 422 28, 422 30, 422 40, 422559, 422560, 422119, 422292, 422300, 422301, 424 7024, 424661, 424840, 424429, 252 95, 252105, 2524081, 2521863, 510112, 510113, 206 51, 206468, 206532, 2065341, 206538, 222840, 222839, 514840, 514839, 134901

Abstract:

The present invention provides a lens care kit for disinfecting and cleaning contact lenses. The lens care kit of the invention allows customers to visually identify when their lenses are disinfected, clean, and ready to wear. The invention is relied on color change to indicate the readiness of disinfection and cleaning of contact lenses.

US Patent:

8091568, Jan 10, 2012

Filed:

Aug 14, 2007

Appl. No.:

12/310190

Inventors:

Jennifer Dawn Lane - Stone Mountain GA, US
Dawn A. Smith - Duluth GA, US

Assignee:

Novartis AG - Basel

International Classification:

B08B 3/04

US Classification:

134 93, 134 941, 134901, 422292

Abstract:

The present invention provides a lens care kit for disinfecting and cleaning contact lenses. The lens care kit of the invention allows customers to visually identify when their lenses are disinfected, clean, and ready to wear. The invention is relied on color change, due to temporally photo-bleaching of a colored lens care solution, to indicate the readiness of disinfection and cleaning of contact lenses.

US Patent:

8268763, Sep 18, 2012

Filed:

Aug 14, 2007

Appl. No.:

12/310189

Inventors:

Jennifer Dawn Lane - Stone Mountain GA, US
Mary Mowrey-McKee - Alpharetta GA, US
Karen Belinda Sentell - Alpharetta GA, US
Karen Frances Lindley - Cumming GA, US

Assignee:

Novartis AG - Basel

International Classification:

C11D 3/386

US Classification:

510114

Abstract:

The present invention provides a lens care kit for disinfecting and cleaning contact lenses. The lens care kit of the invention comprises a colored lens care solution including a colored protein and a proteolytic enzyme. The kit of the invention allows customers to visually identify when their lenses are disinfected, clean, and ready to wear. The invention relies upon a color change to indicate the completion of disinfection and cleaning of contact lenses.

US Patent:

20050038329, Feb 17, 2005

Filed:

Nov 12, 2003

Appl. No.:

10/706208

Inventors:

Carol Morris - Duluth GA, US
Fiona Carney - Atlanta GA, US
Jennifer Lane - Stone Mountain GA, US

International Classification:

A61B005/00
C12Q001/54

US Classification:

600319000, 435014000

Abstract:

The invention provides an in vivo screening assay and an in vitro screening assay for rapid screening of diabetes. A method of the invention includes determining a first glucose concentration in an ocular fluid of a patient; administering orally a load of carbohydrate to the patient; determining a second glucose concentration in an ocular fluid of the patient at a period of time of less than 50 minutes after orally administering of the load of carbohydrate; comparing the second glucose concentration with the first glucose concentration to determine if the patient is likely to be a diabetic. The method of the invention is performed by using a kit of the invention. The kit comprises: (1) a glucose-sensing ophthalmic device and instructions for using the glucose-sensing ophthalmic device to screen for diabetes; or (2) two or more tear-collecting devices, and a testing agent composition which specifically reacts with glucose to form a detectable signal. The glucose-sensing ophthalmic device comprises a testing agent composition which specifically and reversibly interacts with glucose to form a detectable optical signal which changes in a concentration-dependent manner.

US Patent:

20070140911, Jun 21, 2007

Filed:

Feb 15, 2007

Appl. No.:

11/706808

Inventors:

Flona Carney - Atlanta GA, US
Jennifer Lane - Stone Mountain GA, US
Carol Morris - Duluth GA, US

International Classification:

B01L 3/00

US Classification:

422099000

Abstract:

The invention, in one aspect, provides a strip for tear collection. The strip has a first end and an opposite second end and preferably has substantially uniform cross-sections from the first end to the second end. The strip is made of a hydrogel material in substantially dry state. The strip is characterized by having a substantially uniform swelling along the hydrogel strip from the first end to the second end when fully wicked by a tear fluid and by having a correlation between the volume of tear uptake by said strip and the length of the wicked end portion of said strip. A strip of the invention is useful for assay of an analyte of interest in a tear fluid. The invention also provides a method and kits for assaying an analyte of interest (e.g., lactoferrin, glucose, herpes simplex virus, hormones, etc.).