Jennifer F Lo

US Patent:

20220213091, Jul 7, 2022

Filed:

Nov 9, 2021

Appl. No.:

17/522628

Inventors:

- Foster City CA, US
Mark J. Bartlett - Castro Valley CA, US
Jayaraman Chandrasekhar - Redmond WA, US
Julian A. Codelli - Seattle WA, US
John H. Conway - Somerville MA, US
Jennifer L. Cosman - Foster City CA, US
Rao V. Kalla - Cupertino CA, US
Zachary A. Kasun - Seattle WA, US
Musong Kim - Bellevue WA, US
Seung H. Lee - Sammamish WA, US
Jennifer R. Lo - Seattle WA, US
Jennifer A. Loyer-Drew - Seattle WA, US
Scott A. Mitchell - Kenmore WA, US
Thao D. Perry - San Jose CA, US
Gary B. Phillips - Issaquah WA, US
Patrick J. Salvo - Burien WA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
Joshua J. Van Veldhuizen - Seattle WA, US
Suet C. Yeung - Redmond WA, US
Jeff Zablocki - Los Altos CA, US

International Classification:

C07D 471/04
C07D 519/00

Abstract:

The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

US Patent:

20230079863, Mar 16, 2023

Filed:

Mar 25, 2022

Appl. No.:

17/704440

Inventors:

- Foster City CA, US
Daniel H. Byun - Foster City CA, US
Christopher T. Clark - Seattle WA, US
Petr Jansa - Foster City CA, US
Joshua A. Kaplan - Foster City CA, US
Zachary A. Kasun - Seattle WA, US
Jennifer R. Lo - Seattle WA, US
Megan E. Neubig - San Diego CA, US
Nathaniel H. Stanley - San Francisco CA, US
Kirk L. Stevens - Bothell WA, US

International Classification:

C07D 409/14
C07D 405/14
C07D 403/14
C07D 401/14
C07D 495/04
C07D 513/04
C07D 493/10
C07D 491/107
C07D 413/14
C07D 403/04
A61K 45/06

Abstract:

Compounds of formula:wherein the variable substituents are defined herein.

US Patent:

20230013585, Jan 19, 2023

Filed:

May 27, 2021

Appl. No.:

17/331900

Inventors:

- Foster City CA, US
Mark J. Bartlett - Castro Valley CA, US
Jayaraman Chandrasekhar - Redmond WA, US
Julian A. Codelli - Seattle WA, US
John H. Conway - Somerville MA, US
Jennifer L. Cosman - Foster City CA, US
Rao V. Kalla - Cupertino CA, US
Musong Kim - Bellevue WA, US
Seung H. Lee - Sammamish WA, US
Jennifer R. Lo - Seattle WA, US
Jennifer A. Loyer-Drew - Seattle WA, US
Scott A. Mitchell - Kenmore WA, US
Thao D. Perry - San Jose CA, US
Gary B. Phillips - Issaquah WA, US
Patrick J. Salvo - Burien WA, US
Joshua J. Van Veldhuizen - Seattle WA, US
Suet C. Yeung - Redmond WA, US
Jeff Zablocki - Los Altos CA, US

International Classification:

A61K 31/4545
A61K 31/444
A61K 31/5386
C07D 471/04
C07D 519/00

Abstract:

The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

US Patent:

20210115037, Apr 22, 2021

Filed:

Oct 30, 2019

Appl. No.:

16/669346

Inventors:

- Foster City CA, US
Mark J. Bartlett - Castro Valley CA, US
Jayaraman Chandrasekhar - Redmond WA, US
Julian A. Codelli - Seattle WA, US
John H. Conway - Seattle WA, US
Jennifer L. Cosman - Foster City CA, US
Rao V. Kalla - Cupertino CA, US
Zachary A. Kasun - Seattle WA, US
Musong Kim - Bellevue WA, US
Seung H. Lee - Sammamish WA, US
Jennifer R. Lo - Seattle WA, US
Jennifer A. Loyer-Drew - Seattle WA, US
Scott A. Mitchell - Kenmore WA, US
Thao D. Perry - San Jose CA, US
Gary B. Phillips - Issaquah WA, US
Patrick J. Salvo - Burien WA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
Joshua J. Van Veldhuizen - Seattle WA, US
Suet C. Yeung - Redmond WA, US
Jeff Zablocki - Los Altos CA, US

International Classification:

C07D 471/04
C07D 519/00

Abstract:

The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

US Patent:

20200171020, Jun 4, 2020

Filed:

Oct 30, 2019

Appl. No.:

16/668732

Inventors:

- Foster City CA, US
Mark J. Bartlett - Castro Valley CA, US
Jayaraman Chandrasekhar - Redmond WA, US
Julian A. Codelli - Seattle WA, US
John H. Conway - Seattle WA, US
Jennifer L. Cosman - Foster City CA, US
Rao V. Kalla - Cupertino CA, US
Musong Kim - Bellevue WA, US
Seung H. Lee - Sammamish WA, US
Jennifer R. Lo - Seattle WA, US
Jennifer A. Loyer-Drew - Seattle WA, US
Scott A. Mitchell - Kenmore WA, US
Thao D. Perry - San Jose CA, US
Gary B. Phillips - Issaquah WA, US
Patrick J. Salvo - Burien WA, US
Joshua J. Van Veldhuizen - Seattle WA, US
Suet C. Yeung - Redmond WA, US
Jeff Zablocki - Los Altos CA, US

International Classification:

A61K 31/4545
C07D 471/04
A61K 31/444
A61K 31/5386
C07D 519/00

Abstract:

The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.