Phillip Burwell - Snohomish WA, US Zihong Guo - Bellevue WA, US Jennifer Kristine Matson - Renton WA, US Steven Ross Daly - Sammamish WA, US David B. Shine - Sammamish WA, US Gary Lichttenegger - Woodinville WA, US Jean Bishop - Bothell WA, US Nick Yeo - Great Bookham, GB Hugh Narciso - Santa Barbara CA, US
Assignee:
Light Sciences Oncology, Inc. - Bellevue WA
International Classification:
A61B 19/00
US Classification:
128898, 606 7, 606 15
Abstract:
Light generating devices for illuminating portions of vascular tissue, to render photodynamic therapy. In one embodiment, a light source array preferably including a plurality of light emitting diodes, a focusing lens, and a light diffusing element are included in a distal end of a catheter. A balloon is optionally provided to interrupt blood flow that can block the transmission of light, and to center the apparatus in a blood vessel. Optical fibers optionally direct light from the light source to the diffusing element. The light source array can have a radial or linear configuration and can produce more than one wavelength of light for activating different photoreactive agents. Linear light source elements are particularly useful to treat elongate portions of tissue in a vessel. One embodiment intended for use with a conventional balloon catheter integrates light sources into a guidewire.
Phillip Burwell - Snohomish WA, US Zihong Guo - Bellevue WA, US Jennifer Matson - Renton WA, US Steven Daly - Sammamish WA, US David Shine - Sammamish WA, US Gary Lichttenegger - Woodinville WA, US Jean Bishop - Bothell WA, US Nick Yeo - Surrey, GB Hugh Narciso - Santa Barbara CA, US
International Classification:
A61N001/00
US Classification:
600408000
Abstract:
Light generating devices for illuminating portions of vascular tissue, to render photodynamic therapy. In one embodiment, a light source array preferably including a plurality of light emitting diodes, a focusing lens, and a light diffusing element are included in a distal end of a catheter. A balloon is optionally provided to interrupt blood flow that can block the transmission of light, and to center the apparatus in a blood vessel. Optical fibers optionally direct light from the light source to the diffusing element. The light source array can have a radial or linear configuration and can produce more than one wavelength of light for activating different photoreactive agents. Linear light source elements are particularly useful to treat elongate portions of tissue in a vessel. One embodiment intended for use with a conventional balloon catheter integrates light sources into a guidewire.
Phillip Burwell - Snohomish WA, US Zihong Guo - Bellevue WA, US Jennifer Matson - Renton WA, US Steven Daly - Sammamish WA, US David Shine - Sammamish WA, US Gary Lichttenegger - Woodinville WA, US Jean Bishop - Bothell WA, US Nick Yeo - Barns Green, GB Hugh Narciso - Santa Barbara CA, US
Assignee:
Light Sciences Oncology, Inc. - Snoqualmie WA
International Classification:
A61N 1/05 A61M 29/02 F21S 2/00
US Classification:
607122000, 362227000, 606194000
Abstract:
Light sources are incorporated into a guidewire for enabling the ability to render light therapy be added to catheters that do not have that capability. In one exemplary embodiment, a solid guidewire includes a conductive core, and light sources are added to compartments formed in a distal end of the guidewire. In another exemplary embodiment, a light source array is included in a distal end of a hollow guidewire. A plurality of openings are formed into the walls of the hollow guidewire surrounding the array, enabling light to pass through the openings. Conductors extend from the array though the hollow center of the guidewire, to a proximal end of the hollow guidewire. The hollow guidewire can be coated with a conductive material, so that the coating on the guidewire serves as a conductor.
Allen Brenneman - Goshen IN, US Richard G. Sass - Portland OR, US W. Kenneth Ward - Portland OR, US Jennifer Matson - Portland OR, US Dennis Slomski - Tualatin OR, US Robert Bruce - Beaverton OR, US Leslie Wood - Wilsonville OR, US Isaac Federiuk - Tigard OR, US
Assignee:
ISENSE CORPORATION - Wilsonville OR
International Classification:
A61B 19/02 A61F 13/02
US Classification:
602 41, 128869
Abstract:
Embodiments of the present invention provide an adhesive overbandage. In an embodiment, there is provided an adhesive overbandage for use with a biosensor. An exemplary overbandage comprises a frame having an upper surface, a lower surface, an outer boundary and an inner boundary, wherein the inner boundary defines an interior opening configured to receive a monitoring device, adhesive disposed on the lower surface of the frame, and a release liner removably coupled to the adhesive.
Phillip Burwell - Townsend WA, US Zihong Guo - Bellevue WA, US Jennifer K. Matson - Portland OR, US Steven Ross Daly - Sammamish WA, US David B. Shine - Littleton CO, US Gary Lichttenegger - Woodinville WA, US Jean M. Bishop - Bothel WA, US Nick Yeo - Horsham, GB Hugh Narciso - Santa Barbara CA, US James C. Chen - Clyde Hill WA, US William L. Barnard - Maple Valley WA, US Alexei Naimushin - Bellevue WA, US
Assignee:
Light Sciences Oncology, Inc. - Snoqualmie WA
International Classification:
A61N 5/06 A61B 17/00
US Classification:
607 88, 606 13
Abstract:
Light generating devices for illuminating portions of vascular tissue to administer photodynamic therapy, and usable with, or including a distal protection device. A first device includes a hollow tip, a flushing lumen, a guidewire lumen, and at least one of a light source, and a hollow light transmissive shaft that is adapted to accommodate a light source. If desired, the device can include a balloon, so that a portion of a body lumen between the balloon and the distal protection device is isolated when the balloon is inflated. A second device includes inner and outer catheters, the outer catheter including a balloon, and the inner catheter including a light source encompassed by another balloon. Yet another device is a catheter having two balloons and a sleeve extending there between. Within the sleeve, the catheter includes a light source and an expanding member.
Phillip Burwell - Port Townsend WA, US Zihong Guo - Bellevue WA, US Jennifer K. Matson - Portland OR, US Steven Ross Daly - Sammamish WA, US David B. Shine - Littleton CO, US Gary Lichttenegger - Woodinville WA, US Jean M. Bishop - Bothell WA, US Nick Yeo - Horsham, GB Hugh Narciso - Santa Barbara CA, US James C. Chen - Clyde Hill WA, US William L. Barnard - Maple Valley WA, US Alexei N. Naimushin - Bellevue WA, US
Assignee:
Light Sciences Oncology, Inc. - Bellevue WA
International Classification:
A61N 5/06
US Classification:
607 92
Abstract:
Light generating devices for illuminating portions of vascular tissue to administer photodynamic therapy, and usable with, or including a distal protection device. A first device includes a hollow tip, a flushing lumen, a guidewire lumen, and at least one of a light source, and a hollow light transmissive shaft that is adapted to accommodate a light source. If desired, the device can include a balloon, so that a portion of a body lumen between the balloon and the distal protection device is isolated when the balloon is inflated. A second device includes inner and outer catheters, the outer catheter including a balloon, and the inner catheter including a light source encompassed by another balloon. Yet another device is a catheter having two balloons and a sleeve extending there between. Within the sleeve, the catheter includes a light source and an expanding member.
Medical Apparatus Employing Flexible Light Structures And Methods For Manufacturing Same
Phillip Burwell - Snohomish WA, US James C. Chen - Clyde Hill WA, US Zihong Guo - Bellevue WA, US Steven R. Daly - Sammamish WA, US David B. Shine - Littleton CO, US Gary Lichttenegger - Woodinville WA, US Jennifer K. Matson - Renton WA, US Jean Bishop - Issaquah WA, US Nick Yeo - Horsham, GB Hugh Narciso - Santa Barbara CA, US
Assignee:
Light Sciences Oncology, Inc. - Bellevue WA
International Classification:
A61B 1/06
US Classification:
600160
Abstract:
A method of manufacture and medical apparatus that provides an apparatus useful in illuminating at least a portion of a lumen of a body. The apparatus includes an elongated flexible member and a polymer encasement portion encasing a plurality of light emitters. The light emitters may be electrically coupled to one another without the use of wire bonds, and in some embodiments may be coupled without intervening electrical paths or traces. A maximum cross-sectional dimension of the polymer encasement portion may be less than twice a dimension of one of the light emitters. In some embodiments the maximum cross-sectional dimension is less than or equal to the sum of the dimension of one of the light emitters and a marginal dimension by which an outer portion of the polymer encasement portion extends beyond the light emitter. Light emitters may be arranged linearly, helically or in partially overlapping back-to-back relation.
Medical Apparatus Employing Flexible Light Structures
Phillip Burwell - Snohomish WA, US James C. Chen - Clyde Hill WA, US Zihong Guo - Bellevue WA, US Steven R. Daly - Sammamish WA, US David B. Shine - Littleton CO, US Jennifer K. Matson - Renton WA, US Jean Bishop - Issaquah WA, US Nick YEO - Horsham, GB Hugh Narciso - Santa Barbara CA, US
Assignee:
Light Sciences Oncology, Inc. - Bellevue WA
International Classification:
A61B 1/06
US Classification:
600178
Abstract:
A method of manufacture and medical apparatus that provides an apparatus useful in illuminating at least a portion of a lumen of a body. The apparatus includes an elongated flexible member and a polymer encasement portion encasing a plurality of light emitters. The light emitters may be electrically coupled to one another without the use of wire bonds, and in some embodiments may be coupled without intervening electrical paths or traces. A maximum cross-sectional dimension of the polymer encasement portion may be less than twice a dimension of one of the light emitters. In some embodiments the maximum cross-sectional dimension is less than or equal to the sum of the dimension of one of the light emitters and a marginal dimension by which an outer portion of the polymer encasement portion extends beyond the light emitter. Light emitters may be arranged linearly, helically or in partially overlapping back-to-back relation.