Jennifer S Parker

US Patent:

50341898, Jul 23, 1991

Filed:

Aug 27, 1985

Appl. No.:

6/769881

Inventors:

Mary E. Cox - Flushing MI
Jennifer W. Parker - Los Angeles CA

Assignee:

The Regents of the University of California - Alameda CA

International Classification:

G01N 3300

US Classification:

422 52

Abstract:

A fluorescent optical probe employed for the analysis of the concentration of an analyte (or material to be analyzed) in a fluid, employs a permeable, transparent polymeric matrix in which a fluorophor is immobilized, with the polymeric material being directly exposed to the fluid being analyzed. The composite material of the probe may be made up of a homogeneous matrix of transparent polymer, fluorescent compound, catalyst(s) and reagents(s) and is employed to measure analyte concentration in a fluid in the environment surrounding the material. For analyzing oxygen, the fluorophor may be 9,10-diphenyl anthracene and the polymer matrix may be poly (dimethyl siloxane), or silicone, with the presence of oxygen quenching the fluorescence of 9,10-diphenyl anthracene. For analyzing the concentration of glucose, the polymeric material may be poly (hydroxyethyl methacrylate), or PHEMA, the fluorophor may be 9,10-diphenyl anthracene, and as catalytic material, glucose oxidase may also be immobilized within the PHEMA matrix to reduce the quenching action of the oxygen, with increased output radiation therefore indicating higher levels of glucose. More generally, the fluorophor, and the catalyst, and other reagents, when utilized, are immobilized, either physically or chemically, in a homogeneous manner throughtout the polymer host.

US Patent:

20220365106, Nov 17, 2022

Filed:

Feb 24, 2022

Appl. No.:

17/679663

Inventors:

- Rockville MD, US
Peter J. BOSCO - Rockville MD, US
Ian D. CHAMBERLIN - Fulton MD, US
Bandele JEFFREY-COKER - Darnestown MD, US
Eric M. JONES - Frederick MD, US
Gary I. KRIVOY - Rockville MD, US
Don E. KRUEGER - Stafford VA, US
Aaron H. LEIMKUEHLER - Upper St. Clair PA, US
Pei-Ming WU - Potomac MD, US
Kim-Xuan NGUYEN - Montgomery Village MD, US
Pankaj OBEROI - Rockville MD, US
Louis W. PANG - Sandy Spring MD, US
Jennifer PARKER - Frederick MD, US
Victor PELLICIER - Monrovia MD, US
Nicholas SAMMONS - Rockville MD, US
George SIGAL - Rockville MD, US
Jacob N. WOHLSTADTER - Potomac MD, US
Michael L. VOCK - Loveland OH, US
Stanley T. SMITH - Schwenksville PA, US
Carl C. STEVENS - Silver Spring MD, US
Rodger D. OSBORNE - Stuart FL, US
Kenneth E. PAGE - Martinsburg WV, US
Michael T. WADE - Urbana MD, US
Jon WILLOUGHBY - Potomac MD, US
Lei WANG - Clarksville MD, US

International Classification:

G01N 35/00
B01L 3/00
B01L 9/00
G16H 40/67
G16H 10/40
G16H 40/40
F24F 11/30
G06K 7/14
G06Q 10/08
G06Q 10/10

Abstract:

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

US Patent:

20210389338, Dec 16, 2021

Filed:

Aug 26, 2021

Appl. No.:

17/412688

Inventors:

- Rockville MD, US
Peter J. BOSCO - Rockville MD, US
Ian D. CHAMBERLIN - Fulton MD, US
Bandele JEFFREY-COKER - Darnestown MD, US
Eric M. JONES - Frederick MD, US
Gary I. KRIVOY - Rockville MD, US
Aaron H. LEIMKUEHLER - Upper St. Claire PA, US
Pei-Ming WU - Potomac MD, US
Kim-Xuan NGUYEN - Montgomery Village MD, US
Pankaj OBEROI - Rockville MD, US
Louis W. PANG - Sandy Spring MD, US
Jennifer PARKER - Frederick MD, US
Victor PELLICIER - Monrovia MD, US
Nicholas SAMMONS - Rockville MD, US
George SIGAL - Rockville MD, US
Jacob N. WOHLSTADTER - Potomac MD, US
Michael L. VOCK - Loveland OH, US
Stanley T. SMITH - Schwenksville PA, US
Carl C. STEVENS - Silver Spring MD, US
Rodger D. OSBORNE - Stuart FL, US
Kenneth E. PAGE - Martinsburg WV, US
Michael T. WADE - Urbana MD, US
Jon WILLOUGHBY - Potomac MD, US
Lei WANG - Clarksville MD, US
Don E. KRUEGER - Stafford VA, US

International Classification:

G01N 35/00
B01L 3/00
B01L 9/00
G16H 40/67
G16H 10/40
G16H 40/40
F24F 11/30
G06K 7/14
G06Q 10/08
G06Q 10/10

Abstract:

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

US Patent:

20200105409, Apr 2, 2020

Filed:

Jul 22, 2016

Appl. No.:

15/746688

Inventors:

- Rocville MD, US
Peter J. Bosco - Rockville MD, US
Ian D. Chamberlin - Fulton MD, US
Bandele Jeffrey-Coker - Darnestown MD, US
Eric M. Jones - Frederick MD, US
Gary I. Krivoy - Rockville MD, US
Don E. Krueger - Stafford VA, US
Aaron H. Leimkuehler - Upper St. Clair PA, US
Pei-Ming Wu - Potomac MD, US
Kim-Xuan Nguyen - Montgomery Village MD, US
Pankaj Oberoi - Rockville MD, US
Louis W. Pang - Sandy Spring MD, US
Jennifer Parker - Frederick MD, US
Victor Pellicier - Monrovia MD, US
Nick Sammons - Rockville MD, US
George Sigal - Rockville MD, US
Jacob Wohlstadter - Potomac MD, US
Mike Vock - Loveland OH, US
Staley T. Smith - Schwenksville PA, US
Carl C. Stevens - Silver Spring MD, US
Roger D. Osborne - Stuart FL, US
Kenneth Page - Martinsburg WV, US
Michael T. Wade - Urbana MD, US
Jon Willoughby - Potomac MD, US
Lei Wang - Clarksville MD, US

International Classification:

G16H 40/67
G06Q 10/08
G06Q 10/10
G16H 10/40
G16H 40/40
G06K 7/14
F24F 11/30

Abstract:

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

US Patent:

20200002755, Jan 2, 2020

Filed:

Sep 13, 2019

Appl. No.:

16/569774

Inventors:

- Frederick MD, US
Peter Qiang QU - New Market MD, US
Alexander PEROV - Germantown MD, US
Jennifer PARKER - Frederick MD, US

International Classification:

C12Q 1/6837
B01L 3/00
C12Q 1/68
B01J 19/00
G01N 33/543

Abstract:

A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.

US Patent:

20190391170, Dec 26, 2019

Filed:

Jan 20, 2017

Appl. No.:

16/319731

Inventors:

- Rockville MD, US
Peter J. BOSCO - Rockville MD, US
Ian D. CHAMBERLIN - Fulton MD, US
Bandele JEFFREY-COKER - Darnestown MD, US
Eric M. JONES - Frederick MD, US
Gary l. KRIVOY - Rockville MD, US
Aaron H. LEIMKUEHLER - Upper St. Claire PA, US
Pei-Ming WU - Potomac MD, US
Kim-Xuan NGUYEN - Montgomery Village MD, US
Pankaj OBEROI - Rockville MD, US
Louis W. PANG - Sandy Spring MD, US
Jennifer PARKER - Frederick MD, US
Victor PELLICIER - Monrovia MD, US
Nick SAMMONS - Rockville MD, US
George SIGAL - Rockville MD, US
Jacob WOHLSTADTER - Potomac MD, US
Mike VOCK - Loveland OH, US
Stanley T. SMITH - Schwenksville PA, US
Carl C. STEVENS - Silver Spring MD, US
Roger D. OSBORNE - Stuart FL, US
Kenneth PAGE - Martinsburg WV, US
Michael T. WADE - Urbana MD, US
Jon WILLOUGHBY - Potomac MD, US
Lei WANG - Clarksville MD, US
Don E. KRUEGER - Stafford VA, US

Assignee:

Meso Scale Technologies, LLC. - Rockville MD

International Classification:

G01N 35/00
B01L 3/00
B01L 9/00

Abstract:

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

US Patent:

20170016052, Jan 19, 2017

Filed:

Sep 29, 2016

Appl. No.:

15/280654

Inventors:

- Frederick MD, US
Peter Qiang QU - New Market MD, US
Alexander PEROV - Germantown MD, US
Jennifer PARKER - Frederick MD, US

International Classification:

C12Q 1/68
B01L 3/00
G01N 33/543
B01J 19/00

Abstract:

A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.

US Patent:

20140287954, Sep 25, 2014

Filed:

Jun 3, 2014

Appl. No.:

14/294683

Inventors:

- Frederick MD, US
Peter Qiang QU - New Market MD, US
Alexander PEROV - Germantown MD, US
Jennifer PARKER - Frederick MD, US

Assignee:

AKONNI BIOSYSTEMS, INC. - Frederick MD

International Classification:

C12Q 1/68

US Classification:

506 9, 506 39, 506 16

Abstract:

A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.