Jennifer M Reed

US Patent:

20210292746, Sep 23, 2021

Filed:

Aug 6, 2019

Appl. No.:

17/266430

Inventors:

- Evanston IL, US
Jennifer L. Reed - Chicago IL, US

International Classification:

C12N 15/10
C12Q 1/6806

Abstract:

Provided herein are methods for enhancing the speed and/or efficiency of a nucleic acid capture using an affinity-tagged capture oligonucleotide (e.g., biotinylated DNA oligo) and an immobilized capture agent (e.g., immobilized avidin/streptavidin). In particular, experiments conducted during development of embodiments herein demonstrate that streptavidin capture of biotinylated nucleic acid complexes occurs more quickly and efficiently at elevated temperatures while simultaneously reducing the amount of nonspecific DNA captured.

US Patent:

20210146351, May 20, 2021

Filed:

Jun 6, 2018

Appl. No.:

16/618698

Inventors:

- Evanston IL, US
Abhishek K. Agarwal - Evanston IL, US
Sally M. McFall - Evanston IL, US
Tom Westberg - Evanston IL, US
Matthew Austin Butzler - Evanston IL, US
Jennifer L. Reed - Evanston IL, US

International Classification:

B01L 3/00
B01L 7/00

Abstract:

Provided herein are devices that facilitate the magnetic separation of an analyte from a sample, and methods of use thereof. In particular embodiments, devices and methods are provided for the trans-interfacial magnetic separation (TIMS) of analytes from a sample.

US Patent:

20200171503, Jun 4, 2020

Filed:

May 24, 2018

Appl. No.:

16/615630

Inventors:

- Evanston IL, US
David M. Kelso - Wilmette IL, US
Jennifer Lynn Reed - Chicago IL, US
Tom Westbrook - Gurnee IL, US

International Classification:

B01L 7/00
C12Q 1/686
B01L 3/00
G01N 21/64

Abstract:

Provided herein are devices and methods for the rapid processing and analysis of samples. In particular, a small-volume sample (e.g., nucleic acid sample) is exposed to (e.g., contacted with) different temperature zones within a device to process (e.g., amplify) and/or analyze (e.g., quantitate) the sample in an assay.

US Patent:

20150037833, Feb 5, 2015

Filed:

Mar 27, 2013

Appl. No.:

14/388200

Inventors:

Mark James Fisher - Highland Park IL, US
Sally M. McFall - Evanston IL, US
Robert D. Hillman - Chicago IL, US
Zachary J. Walker - Chicago IL, US
Jacqueline Rene Groves - Chicago IL, US
Jennifer Reed - Chicago IL, US
David M. Kelso - Wilmette IL, US

Assignee:

Northwestern University - Evanston IL

International Classification:

C12Q 1/24

US Classification:

435 30, 4352831

Abstract:

The present invention relates to a system for collecting and preparing a body fluid sample, the system comprising a sample container () comprising a sample cup () for receiving the sample, said sample cup comprising graduated indicator markings () corresponding to equal increments of sample volume, a removable lid () for sealably covering said sample cup, said lid having an access point which is sealed by a septum, and a removable cap () which is effective to cover said access point, and a delivery device for containing a plurality of predetermined reagent doses which are to be added to a sample within the sample container in the predetermined doses relative to the volume of the sample.