Jennifer K Sullivan

US Patent:

7235058, Jun 26, 2007

Filed:

Sep 11, 2002

Appl. No.:

10/242372

Inventors:

Alexis E. Doty - Carlsbad CA, US
Richard E. Gildersleeve - Carlsbad CA, US
Jennifer E. Sullivan - San Diego CA, US

Assignee:

DJO, LLC - Vista CA

International Classification:

A61F 5/00

US Classification:

602 16, 602 20, 602 26

Abstract:

A lockable hinge for use in orthopedic braces is provided. When used in a knee brace, the present hinge provides a knee-immobilizing brace that assists persons with standing and/or walking. The hinge is easily converted from a locked mode to a free range of motion mode and vice versa. When the hinge is in the locked mode, patients are better able to stand and walk. With the push of a button, the patient can bend his or her knee to sit or lie down more comfortably. When the hinge is in the free range of motion mode, patients are better able to participate in physical therapy activities without the hinge locking.

US Patent:

7311687, Dec 25, 2007

Filed:

Apr 4, 2005

Appl. No.:

11/098158

Inventors:

Carl Hoffmeier - Solana Beach CA, US
Jennifer Sullivan - San Pedro CA, US
John Martin - Oceanside CA, US
Colin Seth Gregersen - Cardiff by the Sea CA, US

Assignee:

DJO, LLC - Vista CA

International Classification:

A61F 5/00

US Classification:

602 26, 602 16, 602 25

Abstract:

An osteoarthritis brace having relatively large semi-rigid cuffs for abutting the wearer's thigh and calf. In one embodiment, the semi-rigid cuffs are secured to rigid cuffs of the brace only on one side and in substantially a center of the rigid cuffs. The semi-rigid cuffs bear reaction forces created by a medial/lateral force applied to the wearer's knee by a hinge of the brace. The semi-rigid cuffs provide flesh containment, distribute loads over a large portion of the wearer's flesh, eliminate pinch points and provide enhanced fitting capabilities.

US Patent:

7722555, May 25, 2010

Filed:

Jun 26, 2007

Appl. No.:

11/768868

Inventors:

Alexis E. Doty - Carlsbad CA, US
Richard E. Gildersleeve - Carlsbad CA, US
Jennifer E. Sullivan - San Diego CA, US

Assignee:

DJO, LLC - Vista CA

International Classification:

A61F 5/00

US Classification:

602 16, 602 23, 602 27

Abstract:

A lockable hinge for use in orthopedic braces is provided. When used in a knee brace, the present hinge provides a knee-immobilizing brace that assists persons with standing and/or walking. The hinge is easily converted from a locked mode to a free range of motion mode and vice versa. When the hinge is in the locked mode, patients are better able to stand and walk. With the push of a button, the patient can bend his or her knee to sit or lie down more comfortably. When the hinge is in the free range of motion mode, patients are better able to participate in physical therapy activities without the hinge locking.

US Patent:

20210261625, Aug 26, 2021

Filed:

Jan 29, 2021

Appl. No.:

17/162356

Inventors:

- Cambridge MA, US
Xiaoying Jin - Cambridge MA, US
Lin Liu - Cambridge MA, US
Catherine O'Riordan - Cambridge MA, US
Jennifer Sullivan - Cambridge MA, US

International Classification:

C07K 14/005
C12N 15/86

Abstract:

Provided herein are modified adeno-associated viral (AAV) capsid proteins, compositions (e.g., rAAV) comprising the capsid proteins, and nucleic acids encoding the capsid proteins. The AAV capsids provided herein confer retinal cell tropism and/or corneal cell tropism, and mediate improved transduction efficiency in clinically relevant ocular cell types such as photoreceptors and/or corneal endothelial cells. Also provided are nucleic acids encoding the capsid proteins, and AAV particles comprising the capsid proteins.

US Patent:

20170096683, Apr 6, 2017

Filed:

May 2, 2015

Appl. No.:

15/308335

Inventors:

- Cambridge MA, US
Jennifer SULLIVAN - Hudson MA, US
Lisa M. STANEK - Natick MA, US

International Classification:

C12N 15/86
C12N 15/113
A61K 48/00
C12N 7/00

Abstract:

Provided herein are improved rAAV (e.g., rAAV2, rAAVrh8R, etc.) for enhanced gene therapy of ocular disorders or CNS disorders wherein the rAAV comprise one or more substitutions of amino acids that interact with heparan sulfate proteoglycan. The invention provides methods for improved transduction of retinal cells and methods for treating ocular diseases with improved compositions of rAAV particles. Further provided herein are improved recombinant adeno-associated virus (rAAV) (e.g., rAAV2, rAAVrh8R, etc.) for enhanced gene therapy of disorders of the CNS. The invention provides methods for delivering the rAAV to the CNS, methods for treating disorders of the CNS with improved compositions of rAAV particles, and kits for delivering the rAAV to the CNS and/or treating a CNS disorder.