Jennifer Lee Vance

US Patent:

7655641, Feb 2, 2010

Filed:

Feb 10, 2004

Appl. No.:

10/542579

Inventors:

Scott Eugene Conner - Indianapolis IN, US
Lynn Stacy Gossett - Indianapolis IN, US
Jonathan Edward Green - Avon IN, US
Nathan Bryan Mantlo - Brownsburg IN, US
Donald Paul Matthews - Indianapolis IN, US
Daniel Ray Mayhugh - Carmel IN, US
Daryl Lynn Smith - Fishers IN, US
Jennifer Ann Vance - San Jose CA, US
Xiaodong Wang - Carmel IN, US
Alan M Warshawsky - Carmel IN, US
Yanping Xu - Fishers IN, US
Guoxin Zhu - Noblesville IN, US

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 31/66
A61K 31/38
C07D 409/12
C07D 209/04

US Classification:

514141, 514443, 548467, 549 51, 549 52, 549 54, 549 55

Abstract:

The present invention is directed to a compound of Formula (I): and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.

US Patent:

20050075378, Apr 7, 2005

Filed:

May 24, 2002

Appl. No.:

10/477405

Inventors:

Lynn Gossett - Indianapolis IN, US
Jonathan Green - Greencastle IN, US
James Henry - Indianapolis IN, US
Winton Jones - Carmel IN, US
Donald Matthews - Indianapolis IN, US
Quanrong Shen - Fishers IN, US
Daryl Smith - Fishers IN, US
Jennifer Vance - San Jose CA, US
Alan Warshawsky - Carmel IN, US
Maria Gonzalez-Garcia - Madrid, ES

International Classification:

C07D277/18
C07D263/52
A61K031/426
A61K031/421
A61K031/4164

US Classification:

514365000, 514374000, 514396000, 514541000, 548200000, 548217000, 548335100

Abstract:

The present invention is directed to a compound of formula I, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomer thereof, which are useful in treating Syndrome X, Type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to Syndrome X as well as cardiovascular diseases.

US Patent:

20080167310, Jul 10, 2008

Filed:

Oct 3, 2007

Appl. No.:

11/866568

Inventors:

Lynn Stacy Gossett - Indianapolis IN, US
Jonathan Edward Green - Greencastle IN, US
James Robert Henry - Indianapolis IN, US
Winton Dennis Jones - Carmel IN, US
Donald Paul Matthews - Indianapolis IN, US
Quanrong Shen - Fishers IN, US
Daryl Lynn Smith - Fishers IN, US
Jennifer Ann Vance - San Jose CA, US
Alan M. Warshawsky - Carmel IN, US
Maria Rosario Gonzalez-Garcia - Madrid, ES

International Classification:

A61K 31/5377
C07D 413/02
C07D 277/38
A61K 31/421
A61P 3/06
A61P 3/10
A61K 31/426
C07D 263/30

US Classification:

5142368, 544137, 548193, 548235, 514370, 514374

Abstract:

The present invention is directed to a compound of formula I, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomer thereof, which are useful in treating Syndrome X, Type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to Syndrome X as well as cardiovascular diseases.