The Janssen Pharmaceutical Companies of Johnson & Johnson
Discovery Scientist
Ucsd Pharmacology 2013 - Aug 2014
Assistant Adjunct Professor
Merck Cardiometabolic Drug Discovery Fibrosis Group 2013 - Aug 2014
Scientist
University of California, San Diego 2010 - 2013
Assistant Project Scientist
University of California, San Diego 2005 - 2010
Postdoctoral Fellow
Education:
Tianjin Nankai High School
Peking University Health Science Center
Masters, Medicine
Duke University
Doctorates, Doctor of Philosophy, Pharmacology
Peking University Health Science Center
Doctor of Medicine, Doctorates, Bachelors, Bachelor of Medicine
Skills:
Biochemistry Cell Biology Drug Discovery Molecular Biology Pharmacology Animal Models Life Sciences Mitochondria Biotechnology Fibrosis Metabolism Assay Development Genetics Immunohistochemistry In Vitro Cell Culture In Vivo Protein Chemistry Protein Expression Protein Purification Heart Failure Cancer Research Pk/Pd Human Physiology Stem Cell Research Immunofluorescence Protein Engineering Enzymology
Jul 2010 to Jun 2011 manager assistantJiangxi lianchuang electronic (Nanchang) Co., Ltd. Nanchang Jul 2008 to Aug 2009 optical instrument testing
Education:
Stevens Institute of Technology Hoboken, NJ Jul 2013 Master of Engineering in Electrical EngineeringUniversity of Electronic Science and Technology of China Bachelor of Engineering in Microelectronic Technique
Skills:
SKILLS: FPGA design, CMOS IC layout, Digital and analog circuit design
Us Patents
Baculovirus Expression System For Human Interleukin 5 Receptor And Method Of Screening For Interleukin 5 Antagonists
Ji Zhang - Princeton Junction NJ Peng Wang - Edison NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12N 1587 C12N 1563
US Classification:
435 691
Abstract:
A baculovirus/insect cell expression system in which both. alpha. and. beta. subunit of human IL-5 receptor can be over-expressed together in Sf9 cells has been developed. This system is able to express the human high-affinity IL-5 receptors at a very high level and finds use in a screening assay for IL-5 receptor-based antagonists. A preferred embodiment of the screening assay involves the use of peanut agglutinin as lectin in a scintillation proximity assay.
Systems And Methods For Improvements In Scanning And Mapping
- Pittsburgh PA, US Calvin Wade Sheen - Chula Vista CA, US Ji Zhang - Pittsburgh PA, US
International Classification:
G01S 17/89 G01B 11/24
Abstract:
A method of pose calculation for a portable three-dimensional scanning device including a first sensor and a second sensor the method including utilizing data from the first sensor and data from the second sensor to acquire data defining six degrees of freedom of the scanning device to optimize a first pose calculation, receiving data comprising one of data from the first sensor and data from the second sensor, selecting a subset of the six degrees of freedom of the scanning device, utilizing the data from the first sensor and the received data for the selected subset of six degrees of freedom to optimize a second pose, wherein the unselected degrees of freedom are retained from the first pose and storing received data associated with the second camera pose in a point cloud database.
Sulfonamide Derivatives And Pharmaceutical Applications Thereof
- Dongguan, Guangdong, CN Chuanfei JIN - Dongguan, CN Wenhe ZHONG - Dongguan, CN Hongpeng XIE - Dongguan, CN Ji ZHANG - Princeton NJ, US
Assignee:
Sunshine Lake Pharma Co., Ltd. - Dongguan, Guangdong
International Classification:
C07D 295/096 A61K 45/06 A61K 31/495
Abstract:
Provided herein are sulfonamide derivatives or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and their uses for treating Alzheimer's disease. Also provided herein are pharmaceutical compositions containing such compounds, and use of such compounds or pharmaceutical compositions thereof for managing or treating 5-HTreceptor-mediated diseases, especially in the manufacture of a medicament for managing or treating Alzheimer's disease.