Jian Bo Chen

US Patent:

7056737, Jun 6, 2006

Filed:

Feb 13, 2002

Appl. No.:

10/075846

Inventors:

John N. Feder - Belle Mead NJ, US
Liana Lee - North Brunswick NJ, US
Jian Chen - Princeton NJ, US
Nathan O. Siemers - Pennington NJ, US
Han Chang - Princeton Junction NJ, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C12N 5/00

US Classification:

435325, 4353201, 4352523, 435 6, 536 235

Abstract:

The present invention provides novel polynucleotides encoding HGRA4 polypeptides, fragments and homologues thereof. The present invention also provides novel polynucleotides encoding a HGRA4 splice variant, HGRA4sv. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGRA4 and HGRA4sv polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

US Patent:

7073830, Jul 11, 2006

Filed:

Oct 25, 2005

Appl. No.:

11/258303

Inventors:

Jian Chen - Flushing NY, US
Dennis Q. Chen - Flushing NY, US

International Classification:

B60R 19/44

US Classification:

293142, 293109, 293126

Abstract:

A bumper protection device for automobile bumpers to shield the bumpers from impact attaches to the automobile by a fabric shroud which attaches around the hood and trunk latch and suspends an impact resisting padded guard portion, adapted to the vehicle bumper, covering the entire front or rear bumper, the padded guard portion being drawn partially around the sides of the bumper and anchored by at least one elastic strap attached to opposing ends of the bumper guard portion, each elastic strap being further attached to the tires or wheel wells of the automobile retaining the bumper protection device over the entire rear bumper surface and around the sides of the bumper.

US Patent:

7202056, Apr 10, 2007

Filed:

Mar 28, 2003

Appl. No.:

10/403938

Inventors:

Liana M. Lee - Somerset NJ, US
John N. Feder - Belle Mead NJ, US
Shujian Wu - Langhorne PA, US
Jian Chen - Princeton NJ, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C12P 21/06
C12N 15/87
C12N 1/20
C12N 15/74
C07H 21/04

US Classification:

435 691, 435455, 4352523, 4353201, 536 235

Abstract:

The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

US Patent:

7223557, May 29, 2007

Filed:

May 22, 2002

Appl. No.:

10/153244

Inventors:

Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
John N. Feder - Belle Mead NJ, US
Shujian Wu - Langhorne PA, US
Han Chang - Princeton Junction NJ, US
Liana M. Le - San Francisco CA, US
Michael A. Blanar - Malvern PA, US
David Bol - Gaithersburg MD, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C12Q 1/68
C07H 21/04
C12P 21/02
C12N 5/06
C07K 14/705

US Classification:

435 691, 435 701, 4352523, 435325, 4353201, 530350, 536 231, 536 235

Abstract:

The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

US Patent:

7259002, Aug 21, 2007

Filed:

Jan 21, 2004

Appl. No.:

10/761905

Inventors:

John N. Feder - Belle Mead NJ, US
Thomas C. Nelson - Lawrenceville NJ, US
Jian Chen - Princeton NJ, US
Rupalie Meegalla - Boothwyn PA, US
Michael Ramaker - Greenville DE, US
Dong Cheng - Furlong PA, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C12N 9/10
C12N 1/20
C12N 15/00
C07H 21/04

US Classification:

435193, 4352523, 4353201, 536 232

Abstract:

The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing MGAT3 polypeptides, fragments, and homologues thereof. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

US Patent:

7344882, Mar 18, 2008

Filed:

May 10, 2004

Appl. No.:

10/842313

Inventors:

Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
Shujian Wu - Langhorne PA, US
Michael A. Blanar - Malvern PA, US
Paul C. Levesque - Yardley PA, US
Lucy Sun - Newtown PA, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C12N 5/10
C12N 15/12
C12N 15/63
C12N 1/21

US Classification:

435325, 435 691, 4352523, 4353201, 530350, 536 235

Abstract:

The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

US Patent:

7459532, Dec 2, 2008

Filed:

Nov 19, 2007

Appl. No.:

11/985981

Inventors:

Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
Shujian Wu - Langhorne PA, US
Michael A. Blanar - Malvern PA, US
Paul C. Levesque - Yardley PA, US
Lucy Sun - Newtown PA, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07K 14/435
C07K 14/705
C12P 21/02
A61K 38/17

US Classification:

530350, 514 2, 514 12, 536 235, 435 691

Abstract:

The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

US Patent:

7504481, Mar 17, 2009

Filed:

Mar 28, 2003

Appl. No.:

10/405793

Inventors:

Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
John N. Feder - Belle Mead NJ, US
Shujian Wu - Langhorne PA, US
Liana M. Lee - Somerset NJ, US
Michael A. Blanar - Malvern PA, US

Assignee:

Bristol-Meyers Squibb Company - Princeton NJ

International Classification:

C07K 1/00
C12P 21/06
C12P 21/04
C12N 15/00
A61K 39/00

US Classification:

530350, 435 691, 435 697, 4353201, 4241921

Abstract:

The present invention provides novel polynucleotides encoding LTRPC3 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of LTRPC3 polypeptides, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Address:

4010 Parsons Blvd APT 4A, Flushing, NY 11354

Phone:

9176508880

VIN:

5TDDK3EHXBS077406

Make:

TOYOTA

Model:

HIGHLANDER

Year:

2011