Jie Jerry Chen

US Patent:

6653442, Nov 25, 2003

Filed:

Aug 30, 1999

Appl. No.:

09/385328

Inventors:

Conway C. Chang - San Francisco CA
Chee L. Gu - Saratoga CA
Jie Chen - Belmont CA
Deborah A. Steinberg - Saratoga CA
Robert I. Lehrer - Santa Monica CA
Sylvia S. L. Harwig - Woodland Hills CA
Vladimir N. Kokryakov - St. Petersburg, RU

Assignee:

IntraBiotics Pharmaceuticals, Inc. - Mountain View CA

International Classification:

A61K 3804

US Classification:

530324, 530325, 435 691, 4352523, 4353201, 536 231, 514 12, 514 13, 424 49, 424401

Abstract:

Peptide-based compounds containing four invariant cysteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced are useful as preservatives and in preventing, treating, or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin.

US Patent:

20100035234, Feb 11, 2010

Filed:

May 19, 2009

Appl. No.:

12/468779

Inventors:

John Donnelly - Siena, IT
Ping Wu - Danville CA, US
George Santos - Wayland MA, US
Marzia Monica Giuliani - Siena, IT
William Andrews - Emeryville CA, US
Jie Chen - Pleasanton CA, US

Assignee:

Novartis AG - Basel

International Classification:

C12Q 1/70
G01N 33/569
G01N 33/574
G01N 33/571

US Classification:

435 5, 435 72, 435 732, 435 731, 435 722, 435 723, 435 736, 435 733, 435 734, 435 737

Abstract:

The present invention is directed to methods, assays and compositions for implementing such methods and assays for assessing efficacy of individual components in multi-component vaccines and for assessing efficacy of a vaccine against a pathogen. In one aspect, the method of assessing efficacy of a vaccine against a pathogen is a quick assay that tests for an activity correlated with efficacy such as binding in an ELISA rather than requiring the time and expense of an assay that detects actual bactericidal activity. In another aspect, the method for testing the efficacy of an individual component in a multi-component vaccine includes obtaining an immune sample from a subject inoculated with the multi-component vaccine; blocking the portion of the immune sample that recognizes the individual component such as by addition of the individual component, and testing the efficacy of the immune sample to respond to the pathogen.

US Patent:

20100246203, Sep 30, 2010

Filed:

Mar 27, 2009

Appl. No.:

12/412709

Inventors:

Jie Chen - Novi MI, US
Ben Wang - Northville MI, US
Luc Guy Louis Lacroix - West Bloomfield MI, US
Amine Taleb-Bendiab - Ann Arbor MI, US

Assignee:

NORTH AMERICAN LIGHTING, INC. - Farmington Hills MI

International Classification:

B60Q 1/00

US Classification:

362538

Abstract:

A system and method for exterior projection lighting of a vehicle include a generally ellipsoidal faceted reflector disposed on a rear side of a projection lens. First and second focal points of each facet define corresponding reflector focal regions. A semi-conducting light source positioned at an acute angle, such as a single light emitting diode (LED) without a primary optic, emits light toward the reflector from within the first reflector focal region. Reflected light passes through the projection lens to illuminate a desired beam pattern. A curved shade disposed between the projection lens and the light source has at least a portion of a top edge disposed within the second reflector focal region. The shade blocks a portion of reflected light from extending below the optical axis.

US Patent:

60432209, Mar 28, 2000

Filed:

Dec 3, 1997

Appl. No.:

8/984294

Inventors:

Conway C. Chang - San Francisco CA
Jie Chen - Belmont CA
Robert I. Lehrer - Santa Monica CA
Peggy A. Radel - Berkeley CA

Assignee:

IntraBiotics Pharmaceuticals, Inc. - Mountain View CA

International Classification:

A61K 3808
A61K 3810
A61K 3816
C07K 708

US Classification:

514 12

Abstract:

The invention is directed to antimicrobial peptides related to naturally-occurring protegrin peptides, and methods of using the peptides in a variety of contexts, including the treatment or prevention of infections, and diseases related thereto.

US Patent:

59168722, Jun 29, 1999

Filed:

Jul 24, 1996

Appl. No.:

8/685589

Inventors:

Conway Chang - San Francisco CA
Leo Gu - Saratoga CA
Jie Chen - Belmont CA

Assignee:

IntraBiotics Pharmaceuticals, Inc. - Mountain View CA

International Classification:

A61K 3800
A61K 3812

US Classification:

514 9

Abstract:

The present invention provides cyclic peptides having broad spectrum antimicrobial activity. The peptides exhibit improved efficacy, bioavailability and/or serum half-life as compared with non-cyclized analogues.

US Patent:

59943068, Nov 30, 1999

Filed:

Nov 21, 1996

Appl. No.:

8/752852

Inventors:

Conway C. Chang - San Francisco CA
Chee Liang Gu - Saratoga CA
Jie Chen - Belmont CA
Deborah A. Steinberg - Saratoga CA
Robert I. Lehrer - Santa Monica CA
Sylvia S.L. Harwig - late of Woodland Hills CA

Assignee:

IntraBiotics Pharmaceuticals, Inc. - Mountain View CA

International Classification:

A61K 3804
A01N 2500
C12N 1512
C12N 1513

US Classification:

514 13

Abstract:

The invention is directed to antimicrobial peptides related to naturally-occurring protegrin peptides, and methods of using the peptides in a variety of contexts, including the treatment or prevention of infections.

US Patent:

20220417511, Dec 29, 2022

Filed:

Jun 22, 2022

Appl. No.:

17/808212

Inventors:

- Singapore, SG
Ru-Ling LIAO - San Mateo CA, US
Jie CHEN - San Mateo CA, US
Yan YE - San Mateo CA, US

International Classification:

H04N 19/119
H04N 19/105
H04N 19/159
H04N 19/176
H04N 19/46

Abstract:

A method for performing combined inter and intra prediction (CIIP) includes determining the CIIP being enabled for a target block; determining a first intra prediction mode of the target block using a template-based intra mode derivation (TIMD) method; generating an intra predictor of the target block with the first intra prediction mode; and obtaining a final predictor of the target block by weighted averaging the intra predictor of the target block and an inter predictor of the target block.

US Patent:

20220329797, Oct 13, 2022

Filed:

Jun 21, 2022

Appl. No.:

17/807976

Inventors:

- George Town, KY
Yan YE - San Mateo CA, US
Jie CHEN - San Mateo CA, US

International Classification:

H04N 19/119
H04N 19/124
H04N 19/52
H04N 19/176

Abstract:

The present disclosure provides method and apparatus for motion field storage in video coding. An exemplary method includes: determining whether a first uni-prediction motion vector for a first partition of a block and a second uni-prediction motion vector for a second partition of the block are from a same reference picture list; and in response to the first uni-prediction motion vector and the second uni-prediction motion vector being determined to be from the same reference picture list, storing, in a motion field of the block, one of the first uni-prediction motion vector and the second uni-prediction motion vector for a subblock located in a bi-predicted area of the block.