Dan T. Stinchcomb - Fort Collins CO, US Jill A. Livengood - Fort Collins CO, US O'Neil Wiggan - Fort Collins CO, US Richard Kinney - Fort Collins CO, US Jorge Osorio - Mount Horeb WS, US
International Classification:
C12N 7/00 C12N 7/01
US Classification:
4352351
Abstract:
Embodiments herein report methods, compositions and uses for inducing and/or accelerating viral growth. In certain embodiments, methods, compositions and uses generally related to copolymer compositions for inducing viral growth, reducing lag time and/or increasing viral plaque size. In other embodiments, methods, compositions and uses of copolymer compositions can be for inducing flaviviral growth, reducing lag in growth and/or increasing plaque size.
- Cambridge MA, US Isamu TSUJI - Cambridge MA, US Jill A. LIVENGOOD - Fort Collins CO, US Hansi DEAN - Weston MA, US
Assignee:
Takeda Vaccines, Inc. - Cambridge MA
International Classification:
C07K 16/10 A61K 39/42 A61K 45/06 G01N 33/569
Abstract:
The present invention provides isolated monoclonal antibodies, or antigen-binding portions thereof, that bind to ZIKV glycoproteins, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies, or antigen-binding portions thereof, according to the present invention are useful for inhibiting or neutralizing ZIKV activity, thus providing a means of treating or preventing ZIKV infection in humans. The antibodies, or antigen-binding portions thereof, according to the present invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other anti-viral agents or vaccines.
Compositions And Methods For Dengue Virus Chimeric Constructs In Vaccines
Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells.
Compositions, Methods And Uses For Inducing Viral Growth
- Cambridge MA, US Jill A. Livengood - Fort Collins CO, US O'Neil Wiggan - Fort Collins CO, US Richard Kinney - Fort Collins CO, US Jorge Osorio - Mount Horeb WI, US
International Classification:
C12N 7/00
Abstract:
Embodiments herein report methods, compositions and uses for inducing and/or accelerating viral growth. In certain embodiments, methods, compositions and uses generally related to copolymer compositions for inducing viral growth, reducing lag time and/or increasing viral plaque size. In other embodiments, methods, compositions and uses of copolymer compositions can be for inducing flaviviral growth, reducing lag in growth and/or increasing plaque size.
Compositions And Methods For Dengue Virus Chimeric Constructs In Vaccines
Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells.
Compositions, Methods And Uses For Inducing Viral Growth
- Deerfield IL, US Jill A. Livengood - Fort Collins CO, US O'Neil Wiggan - Fort Collins CO, US Richard Kinney - Fort Collins CO, US Jorge Osorio - Mount Horeb WS, US
International Classification:
C12N 7/00
US Classification:
435239
Abstract:
Embodiments herein report methods, compositions and uses for inducing and/or accelerating viral growth. In certain embodiments, methods, compositions and uses generally related to copolymer compositions for inducing viral growth, reducing lag time and/or increasing viral plaque size. In other embodiments, methods, compositions and uses of copolymer compositions can be for inducing flaviviral growth, reducing lag in growth and/or increasing plaque size.
Compositions And Methods For Live, Attenuated Alphavirus Formulations
Daniel T. Stinchcomb - Fort Collins CO, US Jill A. Livengood - Fort Collins CO, US Lazlo Varga - Fort Collins CO, US
Assignee:
INVIRAGEN, INC. - Fort Collins CO
International Classification:
A61K 39/12 A61K 47/26 A61K 47/22 A61K 47/42
US Classification:
4242181
Abstract:
Embodiments herein relate to compositions of and methods for live attenuated alphaviruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated alphaviruses and compositions to reduce inactivation and/or degradation of the live, attenuated alphavirus. In other embodiments, the live, attenuated virus composition may be a vaccine composition. In yet other compositions, a live, attenuated alphavirus composition may include HEPES buffer. In other embodiments, the HEPES buffer may further include a carbohydrate and gelatin and/or a salt.
Takeda Vaccines
Associate Director
Inviragen, Inc. Oct 2007 - May 2013
Scientist Iii
Centers For Disease Control and Prevention 2004 - 2007
Post Doctoral Fellow: American Society For Microbiology
Colorado State University 1999 - 2005
Graduate Student and Post Doctoral Fellow
Takeda Pharmaceuticals 1999 - 2005
Director Analytical Development
Education:
Colorado State University Jan 1, 1999 - Dec 31, 2004
Doctorates, Doctor of Philosophy, Molecular Biology
Santa Clara University Jan 1, 1994 - 1998
Bachelors, Bachelor of Science
Skills:
Vaccines Biotechnology In Vitro Molecular Biology Biochemistry Life Sciences Tissue Culture Elisa Immunology Laboratory Microbiology Lifesciences Cell Culture Clinical Development Protein Chemistry Laboratory Skills Research and Development Pcr Polymerase Chain Reaction
Interests:
Social Services
Name / Title
Company / Classification
Phones & Addresses
Jill Livengood Asm Fellow Ncid/vbi/bz/mpl
Centers For Disease Prevention and Longevity, Inc Administration of Public Health Programs
3150 Rampart Rd, Fort Collins, CO 80521
Jill Livengood Asm Fellow Ncid/vbi/bz/mpl
Centers for Disease Prevention and Longevity, Inc Administrative Public Health Programs
3150 Rampart Rd, Fort Collins, CO 80521
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