Jill A Ray

US Patent:

7115370, Oct 3, 2006

Filed:

Jun 5, 2002

Appl. No.:

10/164103

Inventors:

Jill M. Ray - Rockville MD, US
Teri Heiland - New Market MD, US
Indira Carey - Silver Spring MD, US

Assignee:

Capital Genomix, Inc. - Gaithersburg MD

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435 6, 435 912

Abstract:

The present invention is directed to a method of detecting gene expression and analysis of both known and unknown genes. In the method utilizing combinatorial oligonucleotide PCR™, no single molecular species of DNA gives rise to more than one fragment in a collection of products which are subsequently amplified and representative of each expressed gene. More specifically, the present invention improves known methods by eliminating the recovery of restriction fragments with two identical ends and furthermore regards amplification and isolation of the restriction fragment utilizing a labeled primer.

US Patent:

20030194707, Oct 16, 2003

Filed:

Apr 3, 2002

Appl. No.:

10/114929

Inventors:

Indira Carey - Silver Spring MD, US
Teri Heiland - New Market MD, US
Anna Smith - Gaithersburg MD, US
Jill Ray - Rockville MD, US

Assignee:

Capitol Genomix, Inc.

International Classification:

C12Q001/68
C07H021/02
C07H021/04

US Classification:

435/006000, 536/025400

Abstract:

The present invention is directed to methods and compositions wherein nucleic acids are associated with a solid phase that comprises a carboxylated substrate. In specific embodiments, precipitation of the nucleic acids occurs in the absence of salt.

US Patent:

20060205004, Sep 14, 2006

Filed:

May 11, 2006

Appl. No.:

11/432199

Inventors:

Indira Carey - Silver Spring MD, US
Teri Heiland - New Market MD, US
Anna Smith - Gaithersburg MD, US
Jill Ray - Rockville MD, US

International Classification:

C12Q 1/68
C07H 21/04

US Classification:

435006000, 536025400

Abstract:

The present invention is directed to methods and compositions wherein nucleic acids are associated with a solid phase that comprises a carboxylated substrate. In specific embodiments, precipitation of the nucleic acids occurs in the absence of salt.