Jing Min Li

US Patent:

6563186, May 13, 2003

Filed:

Apr 10, 2002

Appl. No.:

10/119610

Inventors:

Jing Li - Cherry Hill NJ
Xiaoying Huang - Camden NJ

Assignee:

Rutgers, The State University - New Brunswick NJ

International Classification:

H01L 3100

US Classification:

257442, 257 40, 257642

Abstract:

Hybrid crystalline organic-inorganic quantum confined systems are disclosed, which contain alternating layers of a bifunctional organic ligand and a II-VI semiconducting chalcogenide, wherein the semiconducting chalcogenide layers contain chalcogenides have the formula MQ, in which M is independently selected from II-VI semiconductor cationic species and Q is independently selected from S, Se and Te; and the bifunctional organic ligands of each organic ligand layer are bonded by a first functional group to an element M of an adjacent II-VI semiconducting chalcogenide layer and by a second functional group to an element M from the adjacent opposing II-VI semiconducting chalcogenide layer, so that the adjacent opposing II-VI semiconducting chalcogenide layers are linked by the bifunctional organic ligands of the organic ligand layers. Optical absorption experiments show that these systems produce a significant blue shift in their optical absorption edges, 1. 2-1. 5 eV, compared to a shift of 1.

US Patent:

8507647, Aug 13, 2013

Filed:

Dec 18, 2009

Appl. No.:

12/641465

Inventors:

Jing Li - Lansdale PA, US
Andre Lee Pearson - Somerville MA, US

Assignee:

Cubist Pharmaceuticals, Inc. - Lexington MA

International Classification:

C07K 11/02

US Classification:

530317, 514 24

Abstract:

The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against.

US Patent:

20030032027, Feb 13, 2003

Filed:

Feb 12, 2002

Appl. No.:

10/073123

Inventors:

Jing Li - Flushing NY, US
Scott Powers - Greenlawn NY, US

International Classification:

C12Q001/68
G06F019/00
A61K048/00

US Classification:

435/006000, 702/020000, 514/044000

Abstract:

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the WIP1 gene, which are amplified breast, and/or lung, and/or colon, and/or ovarian, and/or prostate cancer genes. The WIP1 gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy; they are also used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

US Patent:

20030044814, Mar 6, 2003

Filed:

Feb 8, 2002

Appl. No.:

10/071838

Inventors:

Jing Li - Flushing NY, US
Scott Powers - Greenlawn NY, US
Phil Xiang - San Francisco CA, US
Yue Peng - South Setauket NY, US

Assignee:

Tularik Inc. - South San Francisco CA

International Classification:

C12Q001/68
G01N033/574
C12P019/34

US Classification:

435/006000, 435/007230, 435/091200

Abstract:

The present invention provides nucleic acid and protein sequences for a novel protein, PRC17, and methods, reagents, and kits for diagnosing and treating cancer in a mammal, e.g., a human. This invention is based upon the discovery that the novel PRC17 is overexpressed and/or amplified in cancer. Methods to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and to treat cancer, by inhibiting the expression and/or activity of PRC17 in a cancer cell are included.

US Patent:

20030099985, May 29, 2003

Filed:

Aug 27, 2002

Appl. No.:

10/228263

Inventors:

Jing Li - Flushing NY, US

International Classification:

C12Q001/68
G06F019/00
G01N033/48
G01N033/50
A61K048/00

US Classification:

435/006000, 702/020000, 514/044000

Abstract:

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the C8FW gene, which are amplified breast and/or brain and/or colon and/or lung and/or prostate and/or ovarian cancer genes. The C8FW gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they are also used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

US Patent:

20040005596, Jan 8, 2004

Filed:

Mar 18, 2003

Appl. No.:

10/390191

Inventors:

Jing Li - Flushing NY, US
Scott Powers - Greenlawn NY, US
Jianxin Yang - Commack NY, US

International Classification:

C12Q001/68
G01N033/574
C07H021/04
A61K048/00

US Classification:

435/006000, 514/044000, 536/023200, 435/007230

Abstract:

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are amplified colon cancer and/or ovarian cancer and/or breast cancer genes. The CTSZ and CD24 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

US Patent:

20040005615, Jan 8, 2004

Filed:

May 22, 2003

Appl. No.:

10/443108

Inventors:

Jing Li - Flushing NY, US
David Mu - Jericho NY, US
Jianxin Yang - Commack NY, US

International Classification:

C12Q001/68
C07H021/04
C12P021/02
C12N005/06
A61K048/00
C07K014/705

US Classification:

435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 514/044000, 536/023500

Abstract:

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the RecQL5, CTXL, USP13, MCL1, and Pellino1 genes, which are amplified in many types of cancer. The RecQL5, CTXL, USP13, MCL1, and Pellino1 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

US Patent:

20040171037, Sep 2, 2004

Filed:

Nov 18, 2003

Appl. No.:

10/715117

Inventors:

Jing Li - Flushing NY, US
Scott Powers - Greenlawn NY, US
Wun Sin - Dix Hills NY, US
Jianxin Yang - Commack NY, US

International Classification:

C12Q001/68
A61K048/00

US Classification:

435/006000, 514/044000

Abstract:

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing genes, which are amplified in many types of cancer. The amplified genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.