Jody A Martin from 2005 Mandelay Pl, San Jose, CA 95138, age 58, Phone: 4084090713

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Author
Ned & Jody Martin Mike Cowdrey

Binding
Hardcover

Publisher
hawk hill press; first edition (december 2, 2011)

ISBN #
5

Single Cell Secretome Analysis
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US Patent:

20220187286, Jun 16, 2022
Filed:

Jan 15, 2021
Appl. No.:

17/151050
Inventors:

- Franklin Lakes NJ, US
Jody Martin - San Jose CA, US
International Classification:

G01N 33/543
G01N 33/68
G01N 33/74
G01N 33/563
Abstract:

Systems, methods, compositions, and kits for measuring secreted factors from cells are disclosed herein, including those capable of determining single cell secretion activity and protein expression and/or gene expression simultaneously. Disclosed herein include solid supports comprising a plurality of capture probes capable of specifically binding to at least one of the plurality of secreted factors secreted by a single cell. Also disclosed herein include secreted factor-binding reagents capable of specifically binding to a secreted factor bound by a capture probe. A secreted factor-binding reagent can comprise a secreted factor-binding reagent specific oligonucleotide comprising a unique factor identifier sequence for the secreted factor-binding reagent.

Measurement Of Protein Expression Using Reagents With Barcoded Oligonucleotide Sequences
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US Patent:

20230125113, Apr 27, 2023
Filed:

Aug 22, 2022
Appl. No.:

17/821449
Inventors:

- Franklin Lakes NJ, US
Christina Chang - Menlo Park CA, US
Eleen Shum - Menlo Park CA, US
Olaf Zoellner - Menlo Park CA, US
James Ghadiali - Menlo Park CA, US
Gretchen Yinbon Lam - Menlo Park CA, US
Eric Jensen - Franklin Lakes NJ, US
Jurg Rohrer - Franklin Lakes NJ, US
Brent Gaylord - Franklin Lakes NJ, US
Jody Martin - Franklin Lakes NJ, US
Jason G. Vidal - Franklin Lakes NJ, US
International Classification:

G01N 33/566
G16B 99/00
G01N 33/50
G01N 33/543
G01N 33/68
C12Q 1/6804
G16Z 99/00
C12N 15/10
C12Q 1/6806
C12Q 1/6823
C12Q 1/6869
C12Q 1/68
Abstract:

Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.

Intracellular Abseq
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US Patent:

20210246492, Aug 12, 2021
Filed:

Feb 11, 2021
Appl. No.:

17/174249
Inventors:

- Franklin Lakes NJ, US
Jody Martin - San Jose CA, US
International Classification:

C12Q 1/6813
C12N 15/117
Abstract:

Disclosed herein include systems, methods, compositions, and kits for performing intracellular AbSeq assays. There are provided, in some embodiments, methods for measuring intracellular target expression. The method can comprise fixing and permeabilizing a plurality of cells before contacting with a plurality of intracellular target-binding reagents capable of specifically binding to an intracellular target. Intracellular target-binding reagents can comprise an intracellular target-binding reagent specific oligonucleotide comprising a unique intracellular target identifier for the intracellular target-binding reagent specific oligonucleotide. The method can further comprise removing the permeabilizing agent and reversing the fixation.

Sample Indexing For Single Cells
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US Patent:

20200385780, Dec 10, 2020
Filed:

Apr 14, 2020
Appl. No.:

16/848241
Inventors:

- FRANKLIN LAKES NJ, US
Christina Fan - San Jose CA, US
Eleen Shum - San Jose CA, US
Jody Martin - San Jose CA, US
James Ghadiali - San Jose CA, US
Katherine Lazaruk - San Jose CA, US
Gretchen Yinbon Lam - San Jose CA, US
International Classification:

C12Q 1/6804
C12Q 1/6816
C12Q 1/6806
C12Q 1/6811
C12Q 1/6809
C12Q 1/6869
C12Q 1/6855
C12Q 1/6865
C12Q 1/6876
G01N 33/532
Abstract:

Disclosed herein include systems, methods, compositions, and kits for sample identification. A sample indexing composition can comprise, for example, a protein binding reagent associated with a sample indexing oligonucleotide. Different sample indexing compositions can include sample indexing oligonucleotides with different sequences. Sample origin of cells can be identified based on the sequences of the sample indexing oligonucleotides. Sample indexing oligonucleotides can be barcoded using barcoded and lengthened using daisy-chaining primers.

Sample Indexing For Single Cells
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US Patent:

20180346970, Dec 6, 2018
Filed:

Mar 27, 2018
Appl. No.:

15/937713
Inventors:

- Menlo Park CA, US
Christina Fan - Menlo Park CA, US
Eleen Shum - Menlo Park CA, US
Jody Martin - Menlo Park CA, US
James Ghadiali - Menlo Park CA, US
Katherine Lazaruk - Menlo Park CA, US
Gretchen Yinbon Lam - Menlo Park CA, US
International Classification:

C12Q 1/6816
C12Q 1/6806
C12Q 1/6811
C12Q 1/6809
C12Q 1/6837
C12Q 1/6804
Abstract:

Disclosed herein include systems, methods, compositions, and kits for sample identification. A sample indexing composition can comprise, for example, a protein binding reagent associated with a sample indexing oligonucleotide. Different sample indexing compositions can include sample indexing oligonucleotides with different sequences. Sample origin of cells can be identified based on the sequences of the sample indexing oligonucleotides. Sample indexing oligonucleotides can be barcoded using barcoded and lengthened using daisy-chaining primers.

Measurement Of Protein Expression Using Reagents With Barcoded Oligonucleotide Sequences
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US Patent:

20180088112, Mar 29, 2018
Filed:

Sep 25, 2017
Appl. No.:

15/715028
Inventors:

- Menlo Park CA, US
- Franklin Lakes NJ, US
Eleen Shum - Menlo Park CA, US
Olaf Zoellner - Menlo Park CA, US
James Ghadiali - Menlo Park CA, US
Gretchen Yinbon Lam - Menlo Park CA, US
Eric Jensen - Franklin Lakes NJ, US
Jurg Rohrer - Franklin Lakes NJ, US
Brent Gaylord - Franklin Lakes NJ, US
Jody Martin - Franklin Lakes NJ, US
Jason G. Vidal - Franklin Lakes NJ, US
International Classification:

G01N 33/566
C12Q 1/68
G01N 33/543
C12N 15/10
Abstract:

Some embodiments disclosed herein provide a plurality of compositions each comprising a protein binding reagent conjugated with an oligonucleotide. The oligonucleotide comprises a unique identifier for the protein binding reagent it is conjugated with, and the protein binding reagent is capable of specifically binding to a protein target. Further disclosed are methods and kits for quantitative analysis of a plurality of protein targets in a sample and for simultaneous quantitative analysis of protein and nucleic acid targets in a sample. Also disclosed herein are systems and methods for preparing a labeled biomolecule reagent, including a labeled biomolecule agent comprising a protein binding reagent conjugated with an oligonucleotide.