John Jay Boniface

US Patent:

7662254, Feb 16, 2010

Filed:

Feb 8, 2007

Appl. No.:

11/704870

Inventors:

Gregory S. Sexton - Fremont CA, US
Alan M. Schoepp - Ben Lomond CA, US
John D. Boniface - Santa Clara CA, US

Assignee:

Lam Research Corporation - Fremont CA

International Classification:

C23F 1/00
H01L 21/306

US Classification:

15634543

Abstract:

Positional relationships are established in a process chamber. A base is configured with a lower electrode surface to support a wafer, and an upper electrode has a lower surface. A drive mounted on the base has a linkage connected to the upper electrode. A fixture placed on the lower surface moves into a desired orientation of the lower electrode. With the upper electrode loosely connected by the linkage to the drive, the fixture transfers the desired orientation to the upper electrode. The linkage is tightened to maintain the desired orientation, the fixture is removed and a process exclusion insert is mounted to the upper electrode. The drive moves the upper electrode and the insert to define an inactive process zone between the upper electrode and the wafer on the lower electrode to protect a central area of the wafer during etching of a wafer edge environ around the central area.

US Patent:

7825227, Nov 2, 2010

Filed:

Nov 9, 2004

Appl. No.:

10/984958

Inventors:

John J. Boniface - Salt Lake City UT, US
Vladimir Kery - Richland WA, US
John M. Peltier - Sandy UT, US
Paul B. Robbins - Park City UT, US
Justin Savage - North Salt Lake UT, US
Moritz Von Rechenberg - Salt Lake City UT, US

Assignee:

Prolexys Pharmaceuticals, Inc. - Salt Lake City UT

International Classification:

A23J 1/00
C12P 21/04

US Classification:

530412, 435 697

Abstract:

The present invention provides a method for purifying a protein complex and the components comprising the complex from a cell, a cell or tissue lysate or a whole organism by employing a combined set of affinity tags of high affinity, specificity and ease of elution. The method involves using a protein or a peptide modified to contain one or more affinity tags separated by one or more specific protease cleavage sites to isolate any interacting proteins or fragments thereof. Specifically exemplified is a method employing a modified bait containing AviTag or GST and a removal tag of Hishexapeptide positioned proximal to the bait such that any excess bait can be efficiently removed from the purified complex yielding enriched interacting proteins prior to subjecting the complex for further identification of individual components. The identification of the proteins or fragments thereof contained in the protein complex will provide new targets for the identification of new pharmaceuticals and diagnostic tools.

US Patent:

7922866, Apr 12, 2011

Filed:

Dec 24, 2009

Appl. No.:

12/647301

Inventors:

Gregory S. Sexton - Fremont CA, US
Alan M. Schoepp - Ben Lomond CA, US
John D. Boniface - Santa Clara CA, US

Assignee:

Lam Research Corporation - Fremont CA

International Classification:

H01L 21/306
C23F 1/00

US Classification:

15634543

Abstract:

Positional relationships are established in a process chamber. A base is configured with a lower electrode surface to support a wafer, and an upper electrode has a lower surface. A drive mounted on the base has a linkage connected to the upper electrode. A fixture placed on the lower surface moves into a desired orientation of the lower electrode. With the upper electrode loosely connected by the linkage to the drive, the fixture transfers the desired orientation to the upper electrode. The linkage is tightened to maintain the desired orientation, the fixture is removed and a process exclusion insert is mounted to the upper electrode. The drive moves the upper electrode and the insert to define an inactive process zone between the upper electrode and the wafer on the lower electrode to protect a central area of the wafer during etching of a wafer edge environ around the central area.

US Patent:

8398875, Mar 19, 2013

Filed:

Mar 14, 2011

Appl. No.:

13/047735

Inventors:

Gregory S. Sexton - Fremont CA, US
Alan M. Schoepp - Ben Lomond CA, US
John D. Boniface - Santa Clara CA, US

Assignee:

Lam Research Corporation - Fremont CA

International Classification:

B44C 1/22

US Classification:

216 71, 216 58, 216 67, 438689, 438706, 438710

Abstract:

Methods for orienting an upper electrode relative to a lower electrode are provided. The lower electrode is configured to have a desired existing orientation in a process chamber to define active and inactive process zones in the process chamber for processing a wafer. The method includes configuring each electrode with a reference surface, where a lower electrode reference surface is in the desired existing orientation and an upper electrode reference surface to be oriented parallel to the lower electrode reference surface. Then, temporarily holding the upper electrode reference surface oriented parallel to the lower electrode reference surface, and securing the upper electrode to a drive to mount the upper electrode reference surface parallel to the lower electrode reference surface. Other method configurations are also disclosed and illustrated.

US Patent:

20220178938, Jun 9, 2022

Filed:

Jun 21, 2021

Appl. No.:

17/352898

Inventors:

- Salt Lake City UT, US
John Jay Boniface - Salt Lake City UT, US
Gregory Charles Critchfield - Holladay UT, US
Tracey Cristine Fleischer - Sandy UT, US

International Classification:

G01N 33/68

Abstract:

The disclosure provides biomarker panels, methods and kits for determining the probability for preterm birth in a pregnant female. The present disclosure is based, in part, on the discovery that certain proteins and peptides in biological samples obtained from a pregnant female are differentially expressed in pregnant females that have an increased risk of developing in the future or presently suffering from preterm birth relative to matched controls. The present disclosure is further based, in part, on the unexpected discovery that panels combining one or more of these proteins and peptides can be utilized in methods of determining the probability for preterm birth in a pregnant female with relatively high sensitivity and specificity. These proteins and peptides disclosed herein serve as biomarkers for classifying test samples, predicting a probability of preterm birth, monitoring of progress of preterm birth in a pregnant female, either individually or in a panel of biomarkers.

US Patent:

20210156870, May 27, 2021

Filed:

Jul 2, 2020

Appl. No.:

16/919947

Inventors:

- Salt Lake City UT, US
John Jay Boniface - Salt Lake City UT, US
Gregory Charles Critchfield - Holladay UT, US
Tracey Cristine Fleischer - Sandy UT, US

International Classification:

G01N 33/68
G16B 20/00

Abstract:

The disclosure provides biomarker panels, methods and kits for determining the probability for preeclampsia in a pregnant female. The present disclosure is based, in part, on the discovery that certain proteins and peptides in biological samples obtained from a pregnant female are differentially expressed in pregnant females that have an increased risk of developing in the future or presently suffering from preeclampsia relative to matched controls. The present disclosure is further based, in part, on the unexepected discovery that panels combining one or more of these proteins and peptides can be utilized in methods of determining the probability for preeclampsia in a pregnant female with relatively high sensitivity and specificity. These proteins and peptides disclosed herein serve as biomarkers for classifying test samples, predicting a probability of preeclampsia, monitoring of progress of preeclampsia in a pregnant female, either individually or in a panel of biomarkers.

US Patent:

20190376978, Dec 12, 2019

Filed:

Jan 23, 2019

Appl. No.:

16/255757

Inventors:

- Salt Lake City UT, US
John Jay Boniface - Salt Lake City UT, US
Gregory Charles Critchfield - Holladay UT, US
Tracey Cristine Fleischer - Sandy UT, US

International Classification:

G01N 33/68

Abstract:

The disclosure provides biomarker panels, methods and kits for determining the probability for preterm birth in a pregnant female. The present disclosure is based, in part, on the discovery that certain proteins and peptides in biological samples obtained from a pregnant female are differentially expressed in pregnant females that have an increased risk of developing in the future or presently suffering from preterm birth relative to matched controls. The present disclosure is further based, in part, on the unexpected discovery that panels combining one or more of these proteins and peptides can be utilized in methods of determining the probability for preterm birth in a pregnant female with relatively high sensitivity and specificity. These proteins and peptides disclosed herein serve as biomarkers for classifying test samples, predicting a probability of preterm birth, monitoring of progress of preterm birth in a pregnant female, either individually or in a panel of biomarkers.

US Patent:

20190198345, Jun 27, 2019

Filed:

Feb 28, 2019

Appl. No.:

16/289428

Inventors:

- Fremont CA, US
Thorsten Lill - Santa Clara CA, US
Richard Janek - Oakland CA, US
John Boniface - San Jose CA, US

International Classification:

H01L 21/311
H01J 37/32
C23F 4/00
C23F 1/12
C23F 1/00
C23C 16/02
H01L 21/3065
H01L 21/3213

Abstract:

A method for performing atomic layer etching (ALE) on a substrate, including the following method operations: performing a surface modification operation on a surface of the substrate, the surface modification operation configured to convert at least one monolayer of the substrate surface to a modified layer; performing a removal operation on the substrate surface, to remove the modified layer from the substrate surface, wherein removing the modified layer includes exposing the substrate surface to a metal complex, such that a ligand exchange reaction occurs between the metal complex and converted species of the modified layer; performing, following the removal operation, a plasma treatment on the substrate surface, the plasma treatment configured to remove residues formed from the exposure of the substrate surface to the metal complex, wherein the residues are volatilized by the plasma treatment; repeating the foregoing operations until a predefined thickness has been etched from the substrate surface.