Hung V. Do - New Hope PA, US Brian E. Rane - Somerset NJ, US John Flanagan - East Windsor NJ, US
International Classification:
C12Q 1/34
US Classification:
435 18
Abstract:
Provided is a method for diagnosing Pompe disease in a patient by measuring acid α-glucosidase activity in a sample from the patient. The invention also provides a method for monitoring the treatment of Pompe disease with specific pharmacological chaperones by measuring acid α-glucosidase activity in a sample from the patient.
Method To Predict Response To Pharmacological Chaperone Treatment Of Diseases
- CRANBRY NJ, US Hung V. Do - New Hope PA, US Xiaoyang Wu - Edison NJ, US John Flanagan - East Windsor NJ, US Brandon Alan Wustman - San Diego CA, US
Assignee:
AMICUS THERAPEUTICS, INC. - CRANBURY NJ
International Classification:
A61K 31/445 C07K 14/00 G01N 33/68 C12Q 1/34
Abstract:
The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining α-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of α-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
Method To Predict Response To Pharmacological Chaperone Treatment Of Diseases
- Cranbury NJ, US Hung V. Do - New Hope PA, US Xiaoyang Wu - Edison NJ, US John Flanagan - East Windsor NJ, US Brandon Alan Wustman - San Diego CA, US
International Classification:
A61K 31/445 C07K 14/00 G01N 33/68 C12Q 1/34
Abstract:
The present invention provides methods to determine whether a patient with a lysosomal storage disorder will benefit from treatment with a specific pharmacological chaperone. The present invention exemplifies an in vitro method for determining α-galactosidase A responsiveness to a pharmacological chaperone such as 1-deoxygalactonojirimycin in a cell line expressing a mutant from of α-galactosidase A. The invention also provides a method for diagnosing Fabry disease in patients suspected of having Fabry disease.
2007 to 2000 Test EngineerStrategic Resources Inc Sierra Vista, AZ 2005 to 2007 Systems Analyst / HF Lab SupervisorInternational Channel Networks Littleton, CO 2000 to 2005 Director of Network OperationsJones International Networks Englewood, CO 1994 to 2000 Uplink ManagerCity & County of Denver Denver, CO 1992 to 1994 Telecommunications EngineerG.E. Government Services Cherry Hill, NJ 1986 to 1992 Video Operations Engineer
Education:
University of Denver Denver, CO 1996 Master of TelecommunicationsEdison State College Trenton, NJ 1990 B.S. in Electrical Engineering Technology
License Records
John Aloysius Flanagan
License #:
26811 - Active
Issued Date:
Sep 12, 2008
Renew Date:
Dec 1, 2015
Expiration Date:
Nov 30, 2017
Type:
Certified Public Accountant
John P Flanagan
License #:
34EI00645800 - Expired
Category:
Electrical Contractors
Issued Date:
Jan 4, 1981
Expiration Date:
Mar 31, 1997
Type:
Electrical Contractor
John G Flanagan
License #:
RS150180A - Expired
Category:
Real Estate Commission
Type:
Real Estate Salesperson-Standard
John J Flanagan
Address:
Phoenixville, PA 19460
License #:
MD043999L - Active
Category:
Medicine
Type:
Medical Physician and Surgeon
John J Flanagan
License #:
MT026585T - Expired
Category:
Medicine
Type:
Graduate Medical Trainee
John P Flanagan
License #:
34EI00645800 - Expired
Category:
Electrical Contractors
Issued Date:
Jan 4, 1981
Expiration Date:
Mar 31, 1997
Type:
Electrical Contractor
Medicine Doctors
Dr. John J Flanagan, Phoenixville PA - MD (Doctor of Medicine)
1260 Valley Forge Rd Suite 102, Phoenixville, PA 19460 6109332444 (Phone)
Procedures:
Aortic Repair, Open or Repair of Arterial Aneurysm, Open Carotid Endarterectomy (CEA) or Excision of Infected Graft Endovascular Repair of Aorta Non-Coronary Angioplasty, Atherectomy, and Stenting
1028 Kennett Way, West Chester, PA 19380 6104319444 (Phone)
Certifications:
Internal Medicine, 1977
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School Georgetown University Graduated: 2027 Medical School Fftzgerald Mercy Hosp Graduated: 2027 Medical School Abington Meml Hosp Graduated: 2027 Medical School Mayo Fdn Graduated: 2027 Medical School Norristown State Hosp Graduated: 2027
John C Flanagan MD 950 5 Ave, New York, NY 10075 2125358783 (phone), 7184423144 (fax)
Denise Sanfilippo MD 11 Ralph Pl STE 311, Staten Island, NY 10304 7184422711 (phone), 7184423144 (fax)
Education:
Medical School Mount Sinai School of Medicine Graduated: 1978
Procedures:
Destruction of Lesion of Retina and Choroid Lens and Cataract Procedures Ophthalmological Exam Retinal Detachment Repair
Conditions:
Cataract Glaucoma
Languages:
English Italian Spanish
Description:
Dr. Flanagan graduated from the Mount Sinai School of Medicine in 1978. He works in New York, NY and 1 other location and specializes in Ophthalmology. Dr. Flanagan is affiliated with New York Eye & Ear Infirmary Of Mount Sinai.
Dr. Flanagan graduated from the Medical College of Pennsylvania in 1985. He works in Phoenixville, PA and specializes in General Surgery and Vascular Surgery. Dr. Flanagan is affiliated with Einstein Medical Center Of Philadelphia and Phoenixville Hospital.
Dr. Flanagan graduated from the University of Connecticut School of Medicine in 1994. He works in Grand Junction, CO and specializes in Family Medicine. Dr. Flanagan is affiliated with Community Hospital and St Marys Hospital & Medical Center.
New Braunfels Rural Health Clinic 705 Landa St STE C, New Braunfels, TX 78130 8306293614 (phone), 8306292438 (fax)
Emergency Service PartnersEmergency Services Partners 600 N Un Ave, New Braunfels, TX 78130 5126100354 (phone), 5124526685 (fax)
Education:
Medical School University of Texas Medical School at San Antonio Graduated: 1982
Languages:
English Spanish
Description:
Dr. Flanagan III graduated from the University of Texas Medical School at San Antonio in 1982. He works in New Braunfels, TX and 1 other location and specializes in Emergency Medicine and Family Medicine. Dr. Flanagan III is affiliated with Christus Santa Rosa Hospital-New Braunfels.
RE/MAX Executive Realty 610 Old Lancaster Road, Bryn Mawr, PA 19010 6105200400 (Office), 6106104435 (Cell), 6108870195 (Fax)
Experience:
12 years
Description:
John has been one of the most successful Realtors on the Main Line for the last decade. He has a natural love of the fast-paced real estate business and a genuine desire to help buyers and sellers reach their goals. A good Realtor has many skill sets: in-depth community and market knowledge, effective communicator, online marketing savvy, home value expert, effective negotiation skills, and a high-quality professional network. But being a great listener is the most important and John listens to his clients. John understands how modern technology has changed the real estate business. Being an early-adapter to all the latest industry trends and technology enables John to service his buyers and sellers at a higher level than most agents. He knows that the traditional practices that made Realtors successful in the past are no longer relevant in today's marketplace, and that these advances need to be embraced and mastered so that his clients fully succeed.
REO / Bank Owned Short sales Residential sales Luxury homes First time home buyers Distressed properties Horse properties Probate Staging Relocation Co-op
Work:
RE/MAX EXECUTIVE REALTY Bryn Mawr, PA 6102564435 (Phone) License #RS277109
Certifications:
ABR e-PRO
Client type:
Home Buyers Home Sellers
Property type:
Single Family Home Condo/Townhome Co-op
Awards:
Prudential Fox & Roach President's Circle 2011 FIVE STAR Real Estate Agent® Award 2010 and 2011 Long & Foster Founders Club 2007 to 2009 Long & Foster Gold Team Member 2003 to 2010 Long & Foster Listor of the Year 2003 RE/MAX 100% Club 2012
Languages:
English
About:
John has been one of the most successful Realtors on the Main Line for the 10 years. He has a natural love of the fast-paced real estate business, for Main Line architecture, and he has genuine desire to help buyers and sellers reach their goals. A good Realtor has many skill sets: in-depth community and market knowledge, effective communicator, online marketing savvy, home value expert, effective negotiation skills, and a high-quality professional network. But being a great listener is the most important and John listens to his clients. John understands how modern technology has changed the real estate business. Being an early-adapter to all the latest trends and technology enables John to service his buyers and sellers at a higher level than the average agent. He knows that the traditional practices that made Realtors successful in the past are no longer relevant in today's marketplace, and that these advances need to be embraced and mastered so that his clients fully succeed. John is up for that challenge.
Name / Title
Company / Classification
Phones & Addresses
John F. Flanagan President
Gw Company Investment Inc Investment
1105 N Market St, Wilmington, DE 19801 PO Box 8985, Wilmington, DE 19899
John Flanagan Manager
Philadelphia Grating Co Inc Mfg Architectural Metalwork · Grating Fabricators
3865 D St, Philadelphia, PA 19124 PO Box 46006, Philadelphia, PA 19160 PO Box 10726, Rock Hill, SC 29731 2154271700, 8033666171, 2157399050
John Flanagan Executive Vice-President
Optometric Glaucoma Society Optometrist's Office
8360 Old York Rd, Melrose Park, PA 19027
John F Flanagan President, Director, President, Director, CEO
THE GOODHEART-WILLCOX COMPANY, INC Books-Publishing/Printing · Book Publishing
18604 W Crk Dr, Tinley Park, IL 60477 Tinley Park, IL 60477 1209 Orange St, Wilmington, DE 19801 124 W Capitol Ave SUITE 1900, Little Rock, AR 72201 7086875000, 7086870315, 8003230440, 7086875068
John K. Flanagan
FRB PROPERTIES, LLC
John Flanagan
J & L CREATIVE, LLC
John J. Flanagan Principal, Medical Doctor, Owner
Associated Surgeons PC General Surgeons · Offices of Physicians, Except Mental Health
1330 Powell St, Norristown, PA 19401 PO Box 100, Ogontz Campus, PA 19001 6102793300
John J. Flanagan President, Principal
Assoc Vein Solutions P C Management Consulting Services
PO Box 732, Phoenixville, PA 19460
Googleplus
John Flanagan
Lived:
Villanova, PA Philadelphia, PA Lafayette Hill, PA Plymouth Meeting, PA Glenolden, PA
Work:
RE/MAX Exectutive Realty - Real estate consultant (2) Prudential Fox & Roach, Realtors - Realtor (12-2) Long & Foster Real Estate, Inc. - Realtor (6-12)
Education:
Kutztown University of Pennsylvania, Monsignor Bonner High School
Relationship:
Married
About:
John lives on the Main Line. It's an easy assumption to make but not every Realtor who services the Main Line actually lives here. John and his family live in Villanova, which is right in the midd...
Tagline:
"Main Line John"
John Flanagan
Education:
Imperial College London - MSc Computing (Software Engineering), University of Limerick - B.Sc. in Computer Systems, St Geralds College, Castlebar
About:
▼▲
Tagline:
An aficionado of technology, that someday hopes to experience Eau Rouge at considerable velocity.
John Flanagan
Education:
McMaster University, Fleming College, Centenial College
About:
Welcome to my profile! Professionally I am an Insurance Broker for Auto, Home, Commercial, Life, Health and so much more. I have Flanagan Insurance my own slice of the Insurance market. I also hav...
Tagline:
Geeking on Google
John Flanagan
Work:
Green Island Interactive - CEO (198)
Education:
Boston College - Computer Science, Carroll School of Management - Computer Science
Tagline:
CEO of Green Island Interactive, Architect of SiteCaddy.com, and General Man About Town
John Flanagan
Work:
Knights of Columbus - Treasurer
Education:
Mercer County Community College - Accounting Management, Montclair State University - Justice/Paralegal, Community College of Philadelphia - Cultural Science and Technology
Tagline:
A Catholic Gentleman
John Flanagan
Lived:
San Francisco, CA Clementon, NJ Philadelphia, PA Washington, DC
The obverse (heads) design features the familiar image of George Washington by John Flanagan, used on the quarter since 1932. It has been restored to bring out subtle details and the beauty of the original.
Date: Apr 23, 2020
Category: More news
Source: Google
Upstate Taxi Lobby Wants Cuomo To Ban Self-Driving Cars Until 'At Least' 2067
Continuing their fight against Uber, Lyft and other ride hailing apps, the Upstate Transportation Association sent a letter to Governor Cuomo, state Senate president John Flanagan and state Assembly speaker Carl Heastie asking them to ban self-driving cars in New York State for at least 50 years.
Date: Jan 05, 2017
Category: Sci/Tech
Source: Google
NY Senate majority leader: No special session by year's end
In a statement released late Friday night, John Flanagan said while discussions on a special session to address issues including bringing ride-sharing apps like Uber to upstate have made progress, there is still work to do.
Date: Dec 25, 2016
Category: U.S.
Source: Google
NYS Legislator leaders blast pay commission after raises denied
In a joint statement, state Assembly Speaker Carl Heastie (D - Bronx) and Senate Majority Leader John Flanagan (R- East Northport) accused the commissioners of acting outside the scope of the pay commission.
ndrew Cuomo, Assembly Speaker Carl Heastie and Senate Majority Leader John Flanagan that would satisfy at least the minimum requirements for both: The Democratic-dominated Assembly would agree to the first passage of legislation paving the way for a constitutional amendment that would allow for th
Date: Jun 17, 2016
Category: U.S.
Source: Google
PFOA photos: Hoosick Falls residents make plea on Twitter
Despite initial talk about holding hearings on the causes of the crisis, state lawmakers backed off in recent months. This week, state Sen. Kathy Marchione, R-Halfmoon, said she supported Senate GOP Leader John Flanagan's continued resistance to holding hearings.
Date: Jun 11, 2016
Category: Health
Source: Google
Queens principal targeted 'every black teacher' for poor reviews
Zanca used slurs to describe these two teachers, John Flanagan and Heather Hightower, saying that Hightower looked like a gorilla in a sweater and asked Assistant Principal Anthony Riccardo if he had seen Flanagan's big lips quivering in a meeting, the suit says.
Skelos ceded power over the Senate's majority conference a week after his arrest to fellow Long Island Republican Sen. John Flanagan As was the case with Silver and his Democrats, GOP support for Skelos eroded quickly as a schism between upstate and downstate conference members began to show.