David J. Robbins - Hanover NH, US Ziqiang Yuan - Burlington VT, US John A. Goetz - Bloomington IN, US
Assignee:
Trustees of Dartmouth College - Hanover NH
International Classification:
A01N 61/00
US Classification:
514 1
Abstract:
The present invention relates to the constitutive activity of the Hedgehog pathway in non-small cell lung carcinoma (NSCLC). A method for diagnosing NSCLC by detecting the level of a component of the Hedgehog pathway is provided, as is a method for identifying subjects that will respond positively to treatment with a Hedgehog pathway antagonist. Methods for treating subjects with cancer or cancers resistant to Hedgehog pathway antagonists are also provided.
Compositions And Methods For Inhibiting Sonic Hedgehog Activity
David Robbins - Hanover NH, US Ziqiang Yuan - Burlington VT, US John Goetz - Bloomington IN, US William Scott - Cincinnati OH, US Sheila Bell - Cincinnati OH, US Claire Schreiner - Cincinnati OH, US
International Classification:
A61K 33/24 A61P 35/00 G01N 33/53
US Classification:
424654000, 435007100
Abstract:
The present invention relates to the use of sonic hedgehog antagonists in the prevention and treatment of cancer and other hyperproliferative diseases or disorders. Methods for identifying such antagonists are also provided.
Apr 2011 to 2000Low Voltage Tech Portland, CT Apr 2010 to Apr 2011Prime Touch Springfield, MA May 2009 to Apr 2010 Project Manager/CarpenterWoods Restoration Newington, CT Oct 2008 to May 2009 Project Manager/CarpenterFour Seasons Roofing East Hartford, CT Jan 1998 to Sep 2008 Owner/Carpenter
Dr. Goetz graduated from the Medical College of Wisconsin School of Medicine in 1979. He works in Port Washington, WI and 1 other location and specializes in Pediatrics. Dr. Goetz is affiliated with Aurora Medical Center Grafton.
The family recently filed a lawsuit in Illinois against the hospital and Walgreens, but now intends to dismiss it and move forwards with this new action in Minnesota, according to their attorney John Goetz.