John Lewis Leach
age ~65
from Sebastian, FL
- Also known as:
-
- John L Leach
- John P Leach
- John Loach
- Jon Leach
- Jon Leech
John Leach Phones & Addresses
- Sebastian, FL
- 4629 Daughtry Blvd E, Jacksonville, FL 32210 • 9047715018
- Houston, TX
- Bronx, NY
- Philadelphia, PA
Real Estate Brokers
John D Leach
view sourceSpecialties:
Purchase Loan
Refinancing
Home Equity
Refinancing
Home Equity
Isbn (Books And Publications)
Improving Science Education: The Contribution of Research
view sourceAuthor
John Leach
ISBN #
0335206468
Us Patents
-
Hippo And Dystrophin Complex Signaling In Cardiomyocyte Renewal
view source -
US Patent:20220411798, Dec 29, 2022
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Filed:Sep 12, 2022
-
Appl. No.:17/931270
-
Inventors:- Houston TX, US
Todd Ryan Heallen - Houston TX, US
John Leach - Houston TX, US -
International Classification:C12N 15/113
A61K 31/713
C12N 7/00
C12N 15/86 -
Abstract:Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
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Dominant Active Yap, A Hippo Effector, Induces Chromatin Accessibility And Cardiomyocyte Renewal
view source -
US Patent:20230063735, Mar 2, 2023
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Filed:Sep 12, 2022
-
Appl. No.:17/931493
-
Inventors:- Houston TX, US
John Leach - Houston TX, US
James F. Martin - Pearland TX, US -
International Classification:A61K 35/34
C07K 14/47
C12N 5/077
A61K 48/00 -
Abstract:The present disclosure encompasses methods for generating cells or tissue from existing cells with one or more mutated variants of Yap. In specific embodiments, the disclosure regards treatment of existing cardiomyocytes with one or more mutated variants of Yap that causes them to divide and generate new cardiomyocytes. In specific cases, the mutated variant of Yap has serine-to-alanine substitutions at 1, 2, 3, 4, 5, 6, or more serines of Yap.
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Dystrophin Glycoprotein Complex Sequesters Yap To Inhibit Cardiomyocyte Proliferation
view source -
US Patent:20210145890, May 20, 2021
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Filed:Jun 1, 2018
-
Appl. No.:16/616880
-
Inventors:- Houston TX, US
Todd Ryan Heallen - Houston TX, US
John Leach - Houston TX, US
James F. Martin - Pearland TX, US -
International Classification:A61K 35/34
A61K 38/17 -
Abstract:Embodiments of the disclosure include methods and compositions related to the proliferation of cardiomyocytes. In particular embodiments, the proliferation of cardiomyocytes is facilitated upon exposure of the cardiomyocytes to agents that affect the sequestering of Yap by dystrophin glycoprotein complex, such agents including those that inhibit DAG1, Yap, or the interaction thereof.
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Hippo And Dystrophin Complex Signaling In Cardiomyocyte Renewal
view source -
US Patent:20210062190, Mar 4, 2021
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Filed:Nov 12, 2020
-
Appl. No.:17/096260
-
Inventors:- Houston TX, US
Todd Ryan Heallen - Houston TX, US
John Leach - Houston TX, US -
International Classification:C12N 15/113
A61K 31/713
C12N 7/00
C12N 15/86 -
Abstract:Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
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Hippo Pathway Deficiency Reverses Systolic Heart Failure Post-Infarction
view source -
US Patent:20200206327, Jul 2, 2020
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Filed:Sep 6, 2018
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Appl. No.:16/644435
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Inventors:- Houston TX, US
John Leach - Houston TX, US -
International Classification:A61K 38/53
A61K 31/7105
C12N 15/113
C07K 16/18
A61P 9/04 -
Abstract:Embodiments of the disclosure include methods and compositions related to treating or reducing the severity or delaying the onset of one or more cardiac conditions in a mammal In particular embodiments, the compositions concern Park2 and its use for a cardiac medical condition. In specific cases, effective amounts of Park2 polynucleotide(s) and/or Park2 polypeptide(s) are provided to an individual in need thereof, including for heart failure, for example. The administration may be locally to the heart, for example.
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Dominant Active Yap, A Hippo Effector, Induces Chromatin Accessibility And Cardiomyocyte Renewal
view source -
US Patent:20200016212, Jan 16, 2020
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Filed:Mar 14, 2018
-
Appl. No.:16/491491
-
Inventors:- Houston TX, US
John Leach - Houston TX, US
James F. Martin - Pearland TX, US -
International Classification:A61K 35/34
C12N 5/077
C07K 14/47 -
Abstract:The present disclosure encompasses methods for generating cells or tissue from existing cells with one or more mutated variants of Yap. In specific embodiments, the disclosure regards treatment of existing cardiomyocytes with one or more mutated variants of Yap that causes them to divide and generate new cardiomyocytes. In specific cases, the mutated variant of Yap has serine-to-alanine substitutions at 1, 2, 3, 4, 5, 6, or more serines of Yap.
-
Hippo And Dystrophin Complex Signaling In Cardiomyocyte Renewal
view source -
US Patent:20200002702, Jan 2, 2020
-
Filed:Aug 19, 2019
-
Appl. No.:16/544209
-
Inventors:- Houston TX, US
Todd Ryan Heallen - Houston TX, US
John Leach - Houston TX, US -
International Classification:C12N 15/113
A61K 31/713
C12N 7/00
C12N 15/86 -
Abstract:Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
-
Hippo And Dystrophin Complex Signaling In Cardiomyocyte Renewal
view source -
US Patent:20190040388, Feb 7, 2019
-
Filed:Oct 18, 2018
-
Appl. No.:16/164550
-
Inventors:- Houston TX, US
Todd Ryan Heallen - Houston TX, US
John Leach - Houston TX, US -
International Classification:C12N 15/113
C12N 7/00
A61K 31/713
C12N 15/86 -
Abstract:Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed.
Medicine Doctors
John M. Leach
view sourceSpecialties:
Diagnostic Radiology, Musculoskeletal Radiology
Work:
Riverside Radiology & Interventional Associates Inc
7651 Stagers Loop, Delaware, OH 43015
7402010222 (phone), 7402010223 (fax)
Riverside Radiology AssocsRiverside Radiology & Interventional Associates
3525 Olentangy Riv Rd STE 5362, Columbus, OH 43214
6143407741 (phone), 6143407742 (fax)
7651 Stagers Loop, Delaware, OH 43015
7402010222 (phone), 7402010223 (fax)
Riverside Radiology AssocsRiverside Radiology & Interventional Associates
3525 Olentangy Riv Rd STE 5362, Columbus, OH 43214
6143407741 (phone), 6143407742 (fax)
Education:
Medical School
Ohio State University College of Medicine
Graduated: 1999
Ohio State University College of Medicine
Graduated: 1999
Languages:
Chinese
English
French
Spanish
English
French
Spanish
Description:
Dr. Leach graduated from the Ohio State University College of Medicine in 1999. He works in Delaware, OH and 1 other location and specializes in Diagnostic Radiology and Musculoskeletal Radiology. Dr. Leach is affiliated with Berger Hospital, Grady Memorial Hospital, Morrow County Hospital, Riverside Methodist Hospital and Springfield Regional Medical Center.
John Clanton Leach
view sourceName / Title
Company / Classification
Phones & Addresses
Administrator
Exus Designs; LLC
Business Services
Business Services
118 Warrenton Houston, Houston, TX 77023
Website: houstoncopier.com
Website: houstoncopier.com
Owner
Michael Pham
Legal Services
Legal Services
440 Louisiana St Ste 900, Houston, TX 77002
Owner
Exus Designs; LLC
Business Services
Business Services
118 Warrenton Houston, Houston, TX 77023
Website: houstoncopier.com
Website: houstoncopier.com
President
EASTON ROD & GUN CLUB, INC
Owner
Michael Pham
Legal Services
Legal Services
440 Louisiana St STE 900, Houston, TX 77002
7132368070
7132368070
Director Information Technology, Technology/Computer Coordinator
The Florida School for The Deaf & The Blind
Specialty Education & Residential Facility
Specialty Education & Residential Facility
207 San Marco Ave, Saint Augustine, FL 32084
9048272200
9048272200
Coordinator
Florida Department of Education
Administrative Educational Programs
Administrative Educational Programs
PO Box 69, Saint Augustine, FL 32085
207 San Marco Ave, Saint Augustine, FL 32084
9048272892
207 San Marco Ave, Saint Augustine, FL 32084
9048272892
JOHN LEACH MAINTENANCE & REPAIR, LLC
Lawyers & Attorneys
John Leach - Lawyer
view sourceSpecialties:
Products Liability
Automotive Warranty Law
Appellate Practice
Criminal
Automobile Warranty
Automotive Warranty Law
Appellate Practice
Criminal
Automobile Warranty
ISLN:
917019577
Admitted:
2002
University:
Arizona State University, M.A., 1992; Miami University, B.A., 1974
Law School:
University of Akron School of Law, J.D., 2002
Plaxo
John Leach
view sourceLondon UKDirector at Leach Lovegrove
John Leach
view sourcePhoenix, Arizona
John Leach
view sourceUKAviation Consultant at self employed Past: Chief Designer at Aviation Traders/Qualitair/FFV/FLS
John Leach
view sourceProject Manager at Alstom Power
John Leach
view sourceoffice worker at BroadLink Communications
John Leach
view sourceThe Lending Company
John Leach
view sourceApex Systems
Classmates
John Leach
view sourceSchools:
Wesley Lakes Elementary School Mcdonough GA 1997-2001
Community:
Ashley Holmes, Cindy Swann, Seth Riggle, Jasmin Welch, Susan Murphy, Mandy Ohearn
John Leach
view sourceSchools:
Mergenthaler Vocational High School 410 Baltimore MD 1982-1986
Community:
Virginia Ginger, William Hayman, David Clarke
John Leach
view sourceSchools:
Oakland Mills High School Columbia MD 1980-1984
Community:
Tammy Tauber, Jim Wine
John Leach
view sourceSchools:
Westside High School Talladega AL 1966-1970
Community:
Roderick Duncan, Linda Richardson, Hugh Morris
John Leach
view sourceSchools:
Sault Ste. Marie High School Sault Ste. Marie MI 1961-1965
Community:
Heather Thomas, Mary Johnston
John Leach
view sourceSchools:
Our Lady Queen of Hope School Detroit MI 1955-1960
Community:
Michael Hammond, Sue Levey, Judith Ricklefs, John Kenney, George Haas, Kathie Caldwell
John Leach
view sourceSchools:
Scott High School North Braddock PA 1962-1966
Community:
Gregory Ridenour, John Stiles, Tony Nicoletti
John Leach
view sourceSchools:
Scott High School North Braddock PA 1962-1966
Community:
Gregory Ridenour, John Stiles, Tony Nicoletti
John Kaiden Leach
view source
John Walter Leach
view source
John Carter Leach
view source
John Flores Leach
view source
John Tracy Leach
view source
John Tyler Leach
view source
John Long Leach
view source
John Leachy Leach
view sourceGoogleplus
John Leach
Work:
Nuclear Medicine/PET Imaging Clinical Trial Consultant - Consultant (2011)
RadMD, Inc. - Project Manager (2011-2011)
BioClinica, Inc. - Development Project Manager (1999-2010)
Capital Health Systems - Senior Nuclear Medicine Technologist (1991-1999)
RadMD, Inc. - Project Manager (2011-2011)
BioClinica, Inc. - Development Project Manager (1999-2010)
Capital Health Systems - Senior Nuclear Medicine Technologist (1991-1999)
Education:
University of Delaware - BioMedical Technology, Delaware Technical Community College - Nuclear Medicine
John Leach
Lived:
Houston TX
Work:
American Lawyer Media - Tax Lawyer Houston
Education:
Huston-Tillotson University
Relationship:
Married
About:
Are you looking for a Houston tax attorney or tax law firm? Here at The Tax Defenders our tax attorneys specialize in dealing with both Federal and State IRS tax controversies throughout the United St...
Tagline:
Tax Lawyer Houston
John Leach
Work:
Totalpost Services plc - Technical Director (2005)
Education:
Heversham Grammar School, Dallam School
Tagline:
Happy go lucky, smiley kind of guy.
John Leach
Lived:
Sebastian, FL
Work:
Port Consolidated
Fl-Petroleum - Sales
Fl-Petroleum - Sales
John Leach
Work:
-N/A-
John Leach
Education:
Ithaca College - BA Drama
Tagline:
Different city every week
John Leach
Work:
Community Computers - Computer Tech
John Leach
Youtube
Myspace
John Leach
view source
John Leach
view sourceNews
Vancouver survivor to speak at Pearl Harbor observance
view source- Some survivors expected to attend this morning's event include Harold Lacy (USS Tennessee) and John Leach (USS California), who were aboard battleships that were primary targets of the Japanese attackers.
- Date: Dec 07, 2012
- Source: Google
Japan earthquake: race to prevent a humanitarian disaster
view source- The British-based charity Shelterbox, which distributes packages containing tents and other vital supplies and usually works in Third World countries, was among those trying to reach them. Its operations director, John Leach, said: Japan is a very rich nation, but the sheer volume of people displaced is what will cause a problem.
- Date: Mar 13, 2011
- Category: Business
- Source: Google
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