John J Macdougall

US Patent:

20030073622, Apr 17, 2003

Filed:

Jun 7, 2001

Appl. No.:

09/877843

Inventors:

Kumud Majumder - Stamford CT, US
Kimberly Spytek - New Haven CT, US
Velizar Tchernev - Branford CT, US
Steven Colman - Gainesville FL, US
Muralidhara Padigaru - Bronx NY, US
Bryan Zerhusen - Branford CT, US
Vladimir Gusev - Madison CT, US
Catherine Burgess - Branford CT, US
Li Li - Branford CT, US
Uriel Malyankar - North Branford CT, US
Esha Gangolli - Madison CT, US
David Stone - Guilford CT, US
John MacDougall - Hamden CT, US
Glennda Smithson - Branford CT, US
Karen Ellerman - Branford CT, US

International Classification:

A61K038/17
G01N033/574
C07H021/04
C12P021/02
C12N005/06
C07K014/435

US Classification:

514/012000, 530/350000, 536/023500, 435/007230, 435/069100, 435/320100, 435/325000

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20030216304, Nov 20, 2003

Filed:

Apr 27, 2001

Appl. No.:

09/844861

Inventors:

Muralidhara Padigaru - Bronx NY, US
Vishnu Mishra - Gainesville FL, US
Kimberly Spytek - New Haven CT, US
William Grosse - Branford CT, US
Edward Szekeres - Branford CT, US
John Alsobrook - Madison CT, US
Catherine Burgess - Wethersfield CT, US
Stacie Casman - North Haven CT, US
Denise Lepley - Branford CT, US
Esha Gangolli - Madison CT, US
John MacDougall - Hamden CT, US
Glennda Smithson - Branford CT, US

International Classification:

A61K038/17
C12P021/02
C07K014/705
C12Q001/68
C07H021/04
C12N005/06

US Classification:

514/012000, 530/350000, 536/023500, 435/069100, 435/320100, 435/325000, 435/006000

Abstract:

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20040005656, Jan 8, 2004

Filed:

Oct 16, 2001

Appl. No.:

09/981566

Inventors:

Ramesh Kekuda - Stamford CT, US
Kimberly Spytek - New Haven CT, US
Stacie Casman - North Haven CT, US
Bryan Zerhusen - Branford CT, US
Li Li - Branford CT, US
Velizar Tchernev - Branford CT, US
Steven Colman - Guilford CT, US
Robert Ballinger - Newington CT, US
Muralidhara Padigaru - Branford CT, US
Adam Wolenc - East Haven CT, US
Suresh Shenoy - Branford CT, US
Shlomit Edinger - New Haven CT, US
Valerie Gerlach - Branford CT, US
Esha Gangolli - Madison CT, US
John MacDougall - Hamden CT, US
Glennda Smithson - Guildford CT, US
John Peyman - New Haven CT, US
David Stone - Guilford CT, US
Erik Gunther - Branford CT, US
Karen Ellerman - Branford CT, US
William Grosse - Branford CT, US
John Alsobrook - Madison CT, US
Denise Lepley - Branford CT, US
Catherine Burgess - Wethersfield CT, US

International Classification:

C07K014/705
C07H021/04
C12P021/02
C12N005/06

US Classification:

435/069100, 435/320100, 435/325000, 530/350000, 536/023500

Abstract:

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20040043928, Mar 4, 2004

Filed:

Aug 1, 2002

Appl. No.:

10/210172

Inventors:

Ramesh Kekuda - Norwalk CT, US
Charles Miller - Guilford CT, US
Meera Patturajan - Branford CT, US
Carol Pena - New Haven CT, US
Daniel Rieger - Branford CT, US
Richard Shimkets - Guilford CT, US
Bryan Zerhusen - Branford CT, US
Li Li - Branford CT, US
Weizhen Ji - Branford CT, US
Muralidhara Padigaru - Branford CT, US
Stacie Casman - North Haven CT, US
Edward Voss - Wallingford CT, US
Ferenc Boldog - North Haven CT, US
Linda Gorman - Branford CT, US
Mario Leite - Milford CT, US
Corine Vernet - Branford CT, US
David Anderson - Branford CT, US
Xiaojia Guo - Branford CT, US
Mei Zhong - Branford CT, US
Valerie Gerlach - Branford CT, US
Luca Rastelli - Guilford CT, US
Tord Hjalt - Lomma, SE
Kimberly Spytek - New Haven CT, US
Shlomit Edinger - New Haven CT, US
Karen Ellerman - Branford CT, US
Uriel Malyankar - Branford CT, US
John MacDougall - Hamden CT, US
David Stone - Guilford CT, US
John Alsobrook - Madison CT, US
Denise Lepley - Branford CT, US
Catherine Burgess - Wethersfield CT, US
Kumud Majumder - Stamford CT, US
Adam Wolenc - East Haven CT, US
Glennda Smithson - Guilford CT, US
Jason Baumgartner - New Haven CT, US

International Classification:

A61K038/17
C07K014/47
C07H021/04
C12P021/02
C12N005/06

US Classification:

514/012000, 530/350000, 536/023200, 435/069100, 435/320100, 435/325000, 530/388100

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20040116671, Jun 17, 2004

Filed:

Feb 5, 2004

Appl. No.:

10/629248

Inventors:

Sudhirdas Prayaga - O'Fallon MO, US
Kumud Majumder - Stamford CT, US
Bruce Taillon - Middletown CT, US
Steven Spaderna - Berlin CT, US
Kimberly Spytek - New Haven CT, US
John MacDougall - New Haven CT, US

International Classification:

C07K014/705
C07H021/04
C07K016/28

US Classification:

530/350000, 530/388220, 435/069100, 435/320100, 435/325000, 536/023500

Abstract:

The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.