John E Mcdevitt

US Patent:

6589779, Jul 8, 2003

Filed:

Jul 14, 2000

Appl. No.:

09/616482

Inventors:

John T. McDevitt - Austin TX
Eric V. Anslyn - Austin TX
Jason B. Shear - Austin TX
Dean P. Neikirk - Austin TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C12M 134

US Classification:

4352887, 4352872

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

6602702, Aug 5, 2003

Filed:

Jul 14, 2000

Appl. No.:

09/616355

Inventors:

John T. McDevitt - Austin TX
Eric V. Anslyn - Austin TX
Jason B. Shear - Austin TX
Dean P. Neikirk - Austin TX

Assignee:

The University of Texas System - Austin TX

International Classification:

C12M 134

US Classification:

4352887, 4352872, 4352884, 4352885, 435 6, 435 4, 435 24, 436518, 436164, 436172, 422 8205, 422 8208

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

6680206, Jan 20, 2004

Filed:

Jul 16, 1999

Appl. No.:

09/354882

Inventors:

John T. McDevitt - Austin TX
Eric V. Anslyn - Austin TX
Jason B. Shear - Austin TX
Dean P. Neikirk - Austin TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 2176

US Classification:

436172, 422 55, 422 681, 422 8205, 422 8206, 422 8208, 436164, 436165, 436174

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

6908770, Jun 21, 2005

Filed:

Apr 7, 1999

Appl. No.:

09/287248

Inventors:

John T. McDevitt - Austin TX, US
Eric V. Anslyn - Austin TX, US
Jason B. Shear - Austin TX, US
Dean P. Neikirk - Austin TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N033/53
G01N033/543

US Classification:

436518, 436164, 436501, 436523, 436524, 436800, 436805, 436807, 436809, 356 38, 356 45, 356 73, 356311, 356335, 422 57, 422 681, 422 79, 422 81, 422 82, 422 8201, 422 8205, 422 8207, 422243, 4352871, 4352872, 4352884, 4352885, 4352887, 435808, 435973

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

7022517, Apr 4, 2006

Filed:

Jul 14, 2000

Appl. No.:

09/616731

Inventors:

John T. McDevitt - Austin TX, US
Eric V. Anslyn - Austin TX, US
Jason B. Shear - Austin TX, US
Dean P. Neikirk - Austin TX, US
Damon V. Borich - Austin TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C12M 1/34
G01N 33/543

US Classification:

4352885, 4352871, 4352873, 4352882, 4352884, 436518, 436524, 436531

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

7316899, Jan 8, 2008

Filed:

Jan 31, 2001

Appl. No.:

09/775343

Inventors:

John T McDevitt - Austin TX, US
Eric V. Anslyn - Austin TX, US
Jason B. Shear - Austin TX, US
Dean P. Neikirk - Austin TX, US

Assignee:

The Board of Regents of The University of Texas System - Austin TX

International Classification:

C12Q 1/68
C12M 1/36
G01N 15/06

US Classification:

435 6, 4352831, 4352872, 4352885, 422 681, 422 8205

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

7491552, Feb 17, 2009

Filed:

Jan 20, 2005

Appl. No.:

11/039054

Inventors:

John T. McDevitt - Austin TX, US
Eric V. Anslyn - Austin TX, US
Jason B. Shear - Austin TX, US
Dean P. Neikirk - Austin TX, US

Assignee:

The Board of Regents of The University of Texas System - Austin TX

International Classification:

G01N 33/543

US Classification:

436518, 436523, 436524, 422 681, 422 81, 422 8201, 422 8207, 4352871, 4352872, 4352884, 4352887, 435 71

Abstract:

A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.

US Patent:

7651868, Jan 26, 2010

Filed:

Dec 13, 2004

Appl. No.:

11/010816

Inventors:

John T. McDevitt - Austin TX, US
Eric V. Anslyn - Austin TX, US
Jason B. Shear - Austin TX, US
Dean P. Neikirk - Austin TX, US
Nick J. Christodoulides - Austin TX, US

Assignee:

The Board of Regents of The University of Texas System - Austin TX

International Classification:

G01N 21/00
G01N 33/00
G01N 21/64
C12M 1/34
C12M 3/00
G01N 33/566
G01N 33/543
G01N 33/545
G01N 21/76
G01N 33/92
G01N 33/44

US Classification:

436518, 422 55, 422 58, 422 681, 422 8205, 422 8208, 4352871, 4352872, 4352883, 4352884, 4352885, 4352887, 436501, 436523, 436531, 436532, 436164, 436172, 436 71, 436 85, 436807, 436809

Abstract:

A system for the rapid characterization of analytes in saliva. In one embodiment, a system for detecting analytes includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.