John T Pearce

US Patent:

6494832, Dec 17, 2002

Filed:

Aug 28, 2000

Appl. No.:

09/649727

Inventors:

Marc D. Feldman - San Antonio TX
Jonathan W. Valvano - Austin TX
John A. Pearce - Austin TX

Assignee:

Conductance Technologies, Inc. - San Antonio TX

International Classification:

A61B 500

US Classification:

600301

Abstract:

An apparatus and method for determining cardiac performance in a patient. The apparatus includes a multifrequency conductance catheter for measuring instantaneous volume of a heart chamber with multifrequencies. The apparatus includes a mechanism for measuring instantaneous pressure of the heart chamber. The apparatus includes a mechanism for separating the multifrequencies. The apparatus includes a mechanism for signal processing the instantaneous volume and the pressure of the heart chamber to identify mechanical strength of the chamber and for automatically producing a plurality of desired waveforms at desired frequencies for the conductance catheter. The processing mechanism is connected to the pressure measuring mechanism, the separating mechanism and the volume measuring mechanism.

US Patent:

7925335, Apr 12, 2011

Filed:

Sep 3, 2004

Appl. No.:

10/568912

Inventors:

Marc D. Feldman - San Antonio TX, US
Jonathan W. Valvano - Austin TX, US
John A. Pearce - Austin TX, US
Chia-Ling Wei - Tainan, TW

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61N 5/04

US Classification:

600513

Abstract:

An apparatus for determining cardiac performance in the patient involving a conductance catheter () for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor () for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor () is in communication with the conductance catheter ().

US Patent:

20090210020, Aug 20, 2009

Filed:

Dec 14, 2006

Appl. No.:

12/086040

Inventors:

Marc D. Feldman - San Antonio TX, US
Jonathan W. Valvano - Austin TX, US
John A. Pearce - Austin TX, US

International Classification:

A61N 1/368
A61B 5/02
A61B 5/0215
A61N 1/39

US Classification:

607 4, 600508, 600486

Abstract:

An apparatus for determining heart transplant rejection of a heart in a patient includes at least two electrodes adapted to be sewn into the heart that span the left ventricle. The apparatus includes a voltage generator adapted to be inserted in the patient which generates a voltage to the two electrodes and senses the resulting voltage from the two electrodes. A method for determining heart transplant rejection of a heart in a patient. A pacemaker for a patient (including bi-ventricular pacing and AICDs). The pacemaker includes an RV lead having four electrodes adapted to be inserted into the RV apex. The pacemaker includes a voltage generator which generates a voltage signal to the electrodes and senses the instantaneous voltage along the length of the RV and determines the real and imaginary components to remove the myocardial components of the septum and RV free wall to determine absolute RV blood volume. The pacemaker includes a battery connected to the voltage generator. The pacemaker includes a defibrillator connected to the battery. The pacemaker can also be a bi-ventricular pacemaker to restore RV and LV synchrony during contraction. A method for assisting a heart of a patient.

US Patent:

20100280397, Nov 4, 2010

Filed:

Jan 28, 2010

Appl. No.:

12/657832

Inventors:

Marc D. Feldman - San Antonio TX, US
John Porterfield - Edmond OK, US
Karthik Raghavan - San Diego CA, US
Jonathan W. Valvano - Austin TX, US
John A. Pearce - Austin TX, US

International Classification:

A61B 5/0215
A61B 5/053
A61B 5/02
A61B 5/08
A61N 1/368

US Classification:

600486, 600547, 600508, 600529, 607 17

Abstract:

An apparatus for determining tissue versus fluid components of an organ include a detector that generates a detector signal based on electrical signals derived from tissue and fluid. The apparatus includes a signal processor in communication with the detector which subtracts in real time a tissue component from the detector signal and produces a fluid volume signal. A method for monitoring a patient's fluid volume of a patient's organ. An apparatus for monitoring a patient's organ. A method for monitoring a patient's organ. A method to piggyback an admittance system onto a AICD/Bi-ventricular Pacemaker for a heart of a patient, in particular a weakened heart having features consistent with congestive heart failure. An apparatus for monitoring an organ, such as a heart, lungs, brain, skeletal muscle, and bladder of a patient which includes a detector which detects the admittance of the organ. The apparatus includes a transmitter in communication with the detector which transmits a wireless signal indicative of the admittance of the organ. A method for monitoring an organ of a patient includes the steps of detecting with a detector the admittance of the organ. There is the step of transmitting with a transmitter in communication with the detector a wireless signal indicative of admittance of the organ.

US Patent:

20110152661, Jun 23, 2011

Filed:

Sep 22, 2010

Appl. No.:

12/924195

Inventors:

Marc D. Feldman - San Antonio TX, US
Anil Tharian George Kottam - London, CA
John Pearce - Austin TX, US
Jonathan Valvano - Austin TX, US
John Porterfield - Austin TX, US

International Classification:

A61B 5/0408
A61B 5/0402

US Classification:

600393, 600509

Abstract:

A method for identifying the viability of ischemic myocardium of a patient. The method includes the steps of measuring in real-time the ischemic myocardium of a beating or non-beating heart. There is the step of determining in real-time whether the ischemic myocardium of the beating or non-beating heart is stunned or is nonviable. An apparatus for identifying the viability of ischemic myocardium of a patient's heart. The apparatus includes an electrode array having at least four electrodes for electrical communication with the heart which produces an array signal. The apparatus includes a processor portion in communication with the array which receives the array signal and determines in real-time whether the ischemic myocardium of the heart is stunned or is nonviable. An apparatus for analyzing living tissue. The apparatus includes an electrode array having at least four electrodes for electrical communication with the tissue which produces an array signal. The apparatus includes an admittance magnitude and phase detection circuit in communication with the array which receives the array signal from the array and produces a detection circuit signal corresponding to phase angle and magnitude of the array and signal. The apparatus includes a processor in communication with the detection circuit which receives the detection circuit signal and determines permittivity and conductivity of the tissue in real-time. A method for analyzing living tissue.

US Patent:

20110196250, Aug 11, 2011

Filed:

Apr 8, 2011

Appl. No.:

13/066201

Inventors:

Marc D. Feldman - San Antonio TX, US
Jonathan W. Valvano - Austin TX, US
John A. Pearce - Austin TX, US
Chia-Ling Wei - Tainan, TW

International Classification:

A61B 5/0402

US Classification:

600513

Abstract:

An apparatus for determining cardiac performance in the patient. The apparatus includes a conductance catheter for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor is in communication with the conductance catheter. Methods for determining cardiac performance in a patient. Apparatuses for determining cardiac performance in a patient.

US Patent:

20120150252, Jun 14, 2012

Filed:

Dec 2, 2011

Appl. No.:

13/373850

Inventors:

Marc D. Feldman - San Antonio TX, US
John Porterfield - Austin TX, US
Erik Larson - Austin TX, US
Jonathan W. Valvano - Austin TX, US
John A. Pearce - Austin TX, US

International Classification:

A61N 1/365
A61N 1/362

US Classification:

607 18, 607 9

Abstract:

An apparatus for treating a heart of a patient includes a first lead and at least a second lead for pacing the heart adapted to be in electrical communication with the heart. The apparatus includes a microcontroller in communication with the first and second leads which triggers the first lead at either different times or the same time from when the microcontroller triggers the second lead. Alternatively, the apparatus includes a microcontroller in communication with the first and second leads that determines heart volume, including stroke volume, end-systolic volume, and calculated values including ejection fraction, from admittance from signals from the first and second leads and uses the admittance as feedback to control heart volume ejected, as measured by stroke volume, calculated values such as ejection fraction, and control end-systolic volume, with respect to the first and second leads. A method for treating the heart of a patient.

US Patent:

D2494329, Sep 19, 1978

Filed:

Dec 22, 1975

Appl. No.:

5/643232

Inventors:

Mary Ellen Pearce - Annandale VA
John Scott Pearce - Annandale VA

International Classification:

D0606
D1102
D3002

US Classification:

D 6183