John T Pham

US Patent:

20200095296, Mar 26, 2020

Filed:

Jun 4, 2018

Appl. No.:

16/619286

Inventors:

- New York NY, US
- La Jolla CA, US
John Pham - La Jolla CA, US
Bjoern Peters - La Jolla CA, US

Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
LA JOLLA INSTITUTE FOR ALLERGY & IMMUNOLOGY - La Jolla CA
THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. - New York NY

International Classification:

C07K 14/47
G01N 33/50
C12N 5/0783
G01N 33/68
C12Q 1/6869
A61P 25/28

Abstract:

The present invention provides methods for assessing whether a subject is at risk of developing a neurological disorder, diagnosing or confirming whether a subject is afflicted with a neurological disorder, assessing a neurological disorder is developing in a subject who has been identified as being at risk of developing the neurological disorder, assessing whether a subject afflicted with a neurological disorder is likely to benefit iron a therapy, assessing whether a subject afflicted with a neurological disorder has benefited from a therapy, treating a subject afflicted with a neurological disorder, and prophylactically treating a subject who has been identified as being at risk, of developing a neurological disorder. The present invention also provides epitopes, compounds and compositions relating to these methods.