John Smart

US Patent:

6440929, Aug 27, 2002

Filed:

Apr 26, 2001

Appl. No.:

09/744777

Inventors:

Sam J. Milstein - Larchmont NY
John E. Smart - Katonah NY
Donald J. Sarubbi - Carmel NY
Monica Leipold - Thornwood NY
Elizabeth Flanders - Ridgefield CT
Doris OToole - Carmel NY
David Gschneidner - Stamford CT

Assignee:

Emisphere Technologies, Inc. - Tarrytown NY

International Classification:

A61K 3800

US Classification:

514 2, 514 3, 514 11, 514 12, 514 21, 514 56, 514563

Abstract:

The present invention relates to pulmonary delivery of active agents. Acylated or sufonated amino acids are used as carriers to facilitate pulmonary delivery of active agents to a target.

US Patent:

6627228, Sep 30, 2003

Filed:

Oct 9, 2001

Appl. No.:

09/889005

Inventors:

Sam J. Milstein - Larchmont NY
Eugene N. Barantsevitch - Scarsdale NY
Nai Fang Wang - Long Island City NY
Jun Liao - Tarrytown NY
John E. Smart - Katonah NY
Richard D. Conticello - Ossining NY
Raphael M. Ottenbrite - Midlothian VA

Assignee:

Emisphere Technologies, Inc. - Tarrytown NY

International Classification:

A61K 914

US Classification:

424489, 424 7816, 424451, 424452, 424464, 424465

Abstract:

Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.

US Patent:

6693073, Feb 17, 2004

Filed:

Jun 14, 2002

Appl. No.:

10/172582

Inventors:

Sam J. Milstein - Larchmont NY
John E. Smart - Katonah NY
Donald J. Sarubbi - Carmel NY
Monica Leipold - Thornwood NY
Elizabeth Flanders - Ridgefield CT
Doris OToole - Carmel NY
David Gschneidner - Stamford CT

Assignee:

Emisphere Technologies, Inc. - Tarrytown NY

International Classification:

A61K 3828

US Classification:

514 3, 514 2, 514 11, 514 12, 514 21, 514 56, 514563

Abstract:

The present invention provides methods for administering an active agent to an animal in need of the agent by the pulmonary route. This method comprises administering via the pulmonary route, a composition comprising (a) an active agent and (b)(i) an acylated amino acid, (ii) a sulfonated amino acid, or (iii) a combination of (i) and (ii). Administration of the compositions of the present invention provide improved pulmonary delivery and greater bioavailability of the active agent than administration of the active agent alone. As a result, lesser amounts of the active agent may be administered to obtain a desired result when contained in the composition of the present invention than when administered alone.

US Patent:

7129274, Oct 31, 2006

Filed:

Nov 6, 2000

Appl. No.:

10/129467

Inventors:

Kelly Kraft - Hopewell Junction NY, US
David Gschneidner - Stamford CT, US
Maria A. P. Boyd - Garrison NY, US
Puchun Liu - Somers NY, US
Pingwah Tang - Elmsford NY, US
Jun Liao - Yorktown Heights NY, US
John E. Smart - Katonah NY, US

Assignee:

Emisphere Technologies Inc. - Tarrytown NY

International Classification:

A01N 37/10
A61K 31/19
C07C 59/48
C07C 59/64
C07C 59/84

US Classification:

514571, 562471

Abstract:

Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

US Patent:

7208483, Apr 24, 2007

Filed:

May 28, 2003

Appl. No.:

10/447608

Inventors:

Sam J. Milstein - Larchmont NY, US
Eugene N. Barantsevitch - Scarsdale NY, US
Nai Fang Wang - Long Island City NY, US
Jun Liao - Tarrytown NY, US
John E. Smart - Katonah NY, US
Richard D. Conticello - Ossining NY, US
Raphael M. Ottenbrite - Midlothian VA, US

Assignee:

Emisphere Technologies, Inc. - Tarrytown NY

International Classification:

A07N 43/30

US Classification:

514166, 514159, 424400

Abstract:

Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.

US Patent:

7727558, Jun 1, 2010

Filed:

Jan 31, 2007

Appl. No.:

11/669649

Inventors:

Sam J. Milstein - Larchmont NY, US
Eugene N. Barantsevitch - Scarsdale NY, US
Nai Fang Wang - Long Island City NY, US
Jun Liao - Yorktown Heights NY, US
John Smart - Katonah NY, US
Richard Conticello - Ossining NY, US
Raphael Ottenbrite - Midlothian VA, US

Assignee:

Emisphere Technologies, Inc. - Tarrytown NY
Virginia Commonwealth University - Richmond VA

International Classification:

A61K 9/50

US Classification:

424501

Abstract:

Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.

US Patent:

7951971, May 31, 2011

Filed:

Jun 13, 2008

Appl. No.:

12/139276

Inventors:

Kelly Kraft - Hopewell Junction NY, US
Maria Aurora P. Boyd - Garrison NY, US
Puchun Liu - Chappaqua NY, US
Pingwah Tang - Elmsford NY, US
Jun Liao - Yorktown Heights NY, US
John Smart - Katonah NY, US

Assignee:

Emisphere Technologies, Inc. - Cedar Knolls NJ

International Classification:

C07C 65/30

US Classification:

562459

Abstract:

Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

US Patent:

8410309, Apr 2, 2013

Filed:

Jul 18, 2006

Appl. No.:

11/458331

Inventors:

Kelly Kraft - Hopewell Junction NY, US
David Gschneidner - Thornwood NY, US
Maria Aurora P. Boyd - Garrison NY, US
Puchun Liu - Chappaqua NY, US
Pingwah Tang - Elmsford NY, US
Jun Liao - Yorktown Heights NY, US
John Smart - Katonah NY, US

Assignee:

Emisphere Technologies, Inc. - Roseland NJ

International Classification:

C07C 59/90
C07C 62/32
C07C 65/40

US Classification:

562471, 562433, 562459, 562465, 562493

Abstract:

Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

Address:

1221 Ave Of The Americas, New York, NY 10020

Phone:

2394950878

VIN:

JTJBM7FX0C5044739

Make:

LEXUS

Model:

GX 460

Year:

2012