John Floyd Willis

US Patent:

6406455, Jun 18, 2002

Filed:

Dec 17, 1999

Appl. No.:

09/465573

Inventors:

John Willis - Shirley MA
Thaddeus Minior - Berlin MA
Robert Gonnelli - Mahwah NJ

Assignee:

BioValve Technologies, Inc. - North Grafton MA

International Classification:

A61M 530

US Classification:

604 68, 604 82, 604191, 604223

Abstract:

Injection devices, such as needleless injection devices, and methods of making and using the same are disclosed.

US Patent:

6490483, Dec 3, 2002

Filed:

Jun 11, 2001

Appl. No.:

09/878573

Inventors:

John Willis - Shirley MA

Assignee:

BioValve Technologies, Inc. - Worcester MA

International Classification:

A61N 130

US Classification:

604 20, 604 21

Abstract:

Electroactive pores, devices including one or more electroactive pores are described, and methods of delivering therapeutic agents using one or more electroactive pores are described.

US Patent:

6548788, Apr 15, 2003

Filed:

Oct 16, 2001

Appl. No.:

09/981007

Inventors:

Gregory Kellogg - Somerville MA
Stephen G. Kieffer-Higgins - Dorchester MA
Bruce L. Carvalho - Watertown MA
Gene A. Davis - Lexington MA
John P. Willis - Shirley Center MA
Ted Minior - Bedford MA
Laura L. Chapman - Somerville MA
Mikayla Kob - Allston MA
Sarah D. Oeltjen - Somerville MA
Shari Ommert - Medford MA
Alec Mian - Cambridge MA

Assignee:

Tecan Trading AG - Baar

International Classification:

H05B 316

US Classification:

219543, 4352831, 4352864, 4352852, 4352871

Abstract:

This system provides methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. Specifically, the system provides a microsystem platform for use with a micromanipulation device to manipulate the platform by rotation, thereby utilizing the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels embedded in the microplatform. The microsystem platforms of the system are also provided having microfluidics components, resistive heating elements, temperature sensing elements, mixing structures, capillary and sacrificial valves, and methods for using these microsystems platforms for performing biological, enzymatic, immunological and chemical assays. An electronic spindle designed rotor capable of transferring electrical signals to and from the microsystem platforms of the system is also provided.

US Patent:

6616627, Sep 9, 2003

Filed:

Jan 5, 2001

Appl. No.:

09/755906

Inventors:

John P. Willis - Shirley MA
Thaddeus G. Minior - Berlin MA

Assignee:

Biovalve Technologies, Inc. - Worcester MA

International Classification:

A61M 530

US Classification:

604 69, 604187, 604190, 604218

Abstract:

An injection device includes a housing having a proximal end and a distal end, the housing defining a distal opening, and a first opening in a side of the housing and between the proximal and distal ends; a propellant disposed inside the housing and spaced from the distal end; and a movable member disposed inside the housing and between the distal end and the propellant, wherein the propellant is in fluid communication with the movable member and the first opening.

US Patent:

6719682, Apr 13, 2004

Filed:

Apr 15, 2003

Appl. No.:

10/414536

Inventors:

Gregory Kellogg - Somerville MA
Stephen G. Kieffer-Higgins - Dorchester MA
Bruce L. Carvalho - Watertown MA
Gene A. Davis - Lexington MA
John P. Willis - Shirley MA
Ted Minior - Bedford MA
Laura L. Chapman - Somerville MA
Mikayla Kob - Allston MA
Sarah D. Oeltjen - Somerville MA
Shari Ommert - Medford MA
Alec Mian - Cambridge MA

Assignee:

Tecan Trading AG - Baar

International Classification:

B04B 900

US Classification:

494 84, 464900

Abstract:

This invention provides methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. Specifically, the invention provides a microsystem platform for use with a micromanipulation device to manipulate the platform by rotation, thereby utilizing the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels embedded in the microplatform. The microsystem platforms of the invention are also provided having microfluidics components, resistive heating elements, temperature sensing elements, mixing structures, capillary and sacrificial valves, and methods for using these microsystems platforms for performing biological, enzymatic, immunological and chemical assays. An electronic spindle designed rotor capable of transferring electrical signals to and from the microsystem platforms of the invention is also provided.

US Patent:

6960184, Nov 1, 2005

Filed:

Jun 18, 2002

Appl. No.:

10/175541

Inventors:

John Willis - Shirley MA, US
Thaddeus Minior - Berlin MA, US
Robert Gonnelli - Mahwah NJ, US

Assignee:

Biovalve Technologies, Inc. - N. Grafton MA

International Classification:

A61M005/30
A61M037/00

US Classification:

604 68, 604 69, 604 70, 604 90, 604191

Abstract:

Injection devices, such as needleless injection devices, and methods of making the using the same are disclosed.

US Patent:

7740607, Jun 22, 2010

Filed:

Feb 22, 2005

Appl. No.:

11/063500

Inventors:

John P. Willis - Shirley MA, US
Thaddeus G. Minior - Berlin MA, US
Robert R. Gonnelli - Mahwah NJ, US

Assignee:

Valeritas, Inc. - Parsippany NJ

International Classification:

A61M 5/30

US Classification:

604 68, 604 82

Abstract:

Injection devices comprising multiple sections, e. g. , modular components, are disclosed. In some embodiments the injection system comprises an upper section comprising a compressed gas reservoir, and one or more lower sections, e. g. , modular components, containing one or more compositions to be injected. Methods of making and using the injection devices are also disclosed.

US Patent:

7806867, Oct 5, 2010

Filed:

Sep 8, 2003

Appl. No.:

10/658116

Inventors:

John P. Willis - Shirley MA, US
Thaddeus G. Minior - Berlin MA, US

Assignee:

Valeritas, Inc. - Parsippany NJ

International Classification:

A61M 37/00

US Classification:

604141, 604 69

Abstract:

An injection device includes a housing having a proximal end and a distal end, the housing defining a distal opening, and a first opening in a side of the housing and between the proximal and distal ends; a propellant disposed inside the housing and spaced from the distal end; and a movable member disposed inside the housing and between the distal end and the propellant, wherein the propellant is in fluid communication with the movable member and the first opening.