Jon K Jacobs

US Patent:

6495100, Dec 17, 2002

Filed:

Dec 22, 1999

Appl. No.:

09/470244

Inventors:

Szu-Min Lin - Laguna Hills CA
Anthony Lemus - Yorba Linda CA
Harold R. Williams - San Clemente CA
Paul Taylor Jacobs - Trabuco Canyon CA
Tralance O. Addy - Coto de Caza CA
Jon Morrell Jacobs - Trabuco Canyon CA

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

A61L 220

US Classification:

422 29, 422 33

Abstract:

A method for sterilizing medical devices and similar instruments in diffusion-restricted containers is provided. The sterilization method includes placing a liquid solution containing vaporizable germicide such as hydrogen peroxide into the diffusion-restricted container and vaporizing the germicide. The containers can be attachable and detachable to a sterilization system, and used as a vacuum chamber. An attachable/detachable container containing an article to be sterilized can be nested with a second container, and the article and inside and outside of the inner container are sterilized. The sterile article inside the nested containers can be transported and the sterile inner container with the sterilized article can removed from the outer container and placed in a sterile environment without contaminating the sterile environment. The sterile article can then be removed from the sterile container and utilized. Alternatively, the sterilization method may include introducing germicide vapor into an attachable/detachable container.

US Patent:

7179419, Feb 20, 2007

Filed:

Oct 31, 2002

Appl. No.:

10/284987

Inventors:

Szu-Min Lin - Laguna Hills CA, US
Anthony Lemus - Villa Park CA, US
Harold R. Williams - San Clemente CA, US
Paul T. Jacobs - Bichnoll UT, US
Tralance O. Addy - Coto de Caza CA, US
Jon M. Jacobs - Pasco WA, US

Assignee:

Johnson & Johnson Medical Div Ethicon, Inc. - Arlington TX

International Classification:

A61L 2/20

US Classification:

422 33, 422 29

Abstract:

A method for sterilizing medical devices and similar instruments in diffusion-restricted containers is provided. The sterilization method includes placing a liquid solution containing vaporizable germicide such as hydrogen peroxide into the diffusion-restricted container and vaporizing the germicide. The containers can be attachable and detachable to a sterilization system, and used as a vacuum chamber. An attachable/detachable container containing an article to be sterilized can be nested with a second container, and the article and inside and outside of the inner container are sterilized. The sterile article inside the nested containers can be transported and the sterile inner container with the sterilized article can removed from the outer container and placed in a sterile environment without contaminating the sterile environment. The sterile article can then be removed from the sterile container and utilized. Alternatively, the sterilization method may include introducing germicide vapor into an attachable/detachable container.

US Patent:

7262208, Aug 28, 2007

Filed:

Apr 30, 2003

Appl. No.:

10/427106

Inventors:

John A. Tucker - San Mateo CA, US
Brian A. Sherer - Ballston Spa NY, US
Ying Zi Xu - Palo Alto CA, US
Louis Brogley - Santa Cruz CA, US
Shon R. Pulley - Hickory Corners MI, US
Jon S. Jacobs - Kalamazoo MI, US
James P. Beck - Kalamazoo MI, US
Varghese John - San Francisco CA, US

Assignee:

Elan Pharmaceuticals, Inc. - So. San Francisco CA
Pharmacia & Upjohn Company - Kalamazoo MI

International Classification:

A61K 31/445
C07D 211/06

US Classification:

514330, 546226, 546210, 546316, 548240, 548250, 5483351, 548470, 549 74, 564152, 514378, 514416, 514588, 514616

Abstract:

The present invention relates to compounds of formula (I):.

US Patent:

60305797, Feb 29, 2000

Filed:

Apr 4, 1996

Appl. No.:

8/628965

Inventors:

Tralance O. Addy - Coto de Caza CA
Paul Taylor Jacobs - Trabuco Canyon CA
Szu-Min Lin - Laguna Hills CA
Jon Morrell Jacobs - Trabuco Canyon CA

Assignee:

Johnson & Johnson Medical, Inc. - New Brunswick NJ

International Classification:

A61L 218
A61L 214

US Classification:

422 28

Abstract:

A method for hydrogen peroxide vapor sterilization of medical devices and similar instruments having long narrow lumens or diffusion restricted areas includes the step of pretreating the article to be sterilized with a dilute solution of hydrogen peroxide prior to exposure to a vacuum or a vacuum followed by plasma. The method is such that, upon vaporization of the solution caused by the vacuum, the hydrogen peroxide remains in contact with the article for a time sufficient to achieve sterilization.

US Patent:

59808250, Nov 9, 1999

Filed:

Dec 18, 1998

Appl. No.:

9/216381

Inventors:

Tralance O. Addy - Coto de Caza CA
Paul Taylor Jacobs - Trabuco Canyon CA
Szu-Min Lin - Laguna Hills CA
Jon Morrell Jacobs - Trabuco Canyon CA

Assignee:

Johnson & Johnson Medical, Inc. - New Brunswick NJ

International Classification:

A61L 216

US Classification:

422 33

Abstract:

A method for hydrogen peroxide vapor sterilization of medical devices and similar instruments having long narrow lumens or diffusion restricted areas includes the step of pretreating the article to be sterilized with a dilute solution of hydrogen peroxide prior to exposure to a vacuum or a vacuum followed by plasma. The method is such that, upon vaporization of the solution caused by the vacuum, the hydrogen peroxide remains in contact with the article for a time sufficient to achieve sterilization.

US Patent:

61745022, Jan 16, 2001

Filed:

Jun 26, 1998

Appl. No.:

9/105491

Inventors:

Tralance O. Addy - Coto de Caza CA
Paul Taylor Jacobs - Trabuco Canyon CA
Szu-Min Lin - Laguna Hills CA
Jon Morrell Jacobs - Trabuco Canyon CA

Assignee:

Ethicon, Inc. - New Brunswick NJ

International Classification:

A61L 220

US Classification:

422242

Abstract:

A sterilized article is within the interior of a diffusion-restricted container. The container substantially prevents entry of microorganisms into the interior thereof. The container has at least one communication port which permits entry of gas and/or vapor into the interior, but prevents entry of microorganisms into the interior.

US Patent:

61326801, Oct 17, 2000

Filed:

Sep 10, 1999

Appl. No.:

9/394538

Inventors:

Tralance O. Addy - Coto de Caza CA
Paul Taylor Jacobs - Trabuco Canyon CA
Szu-Min Lin - Laguna Hills CA
Jon Morrell Jacobs - Trabuco Canyon CA

Assignee:

Ethicon, Inc. - New Brunswick NJ

International Classification:

A61L 220

US Classification:

422 33

Abstract:

A method for sterilizing an article in a diffusion restricted container includes placing the article in a diffusion restricted container with at least one communication port, placing the container in a vacuum chamber, introducing a vaporizable germicide into the container, and reducing the pressure in the vacuum chamber, generating germicide vapor and sterilizing the article. The article to be sterilized can be a diffusion restricted device, such as a hinge, a mated surface, or a lumen. The germicide may be peroxide or peracetic acid.

US Patent:

59619210, Oct 5, 1999

Filed:

Apr 4, 1997

Appl. No.:

8/833375

Inventors:

Tralance O. Addy - Coto de Caza CA
Paul Taylor Jacobs - Trabuco Canyon CA
Szu-Min Lin - Laguna Hills CA
Jon Morrell Jacobs - Trabuco Canyon CA

Assignee:

Johnson & Johnson Medical, Inc. - New Brunswick NJ

International Classification:

A61L 216

US Classification:

422 33

Abstract:

Methods for peroxide vapor sterilization of medical devices and similar instruments having long narrow lumens or diffusion restricted areas includes the step of contacting the article to be sterilized or a diffusion-restricted environment containing said article with a source of peroxide prior to exposure to a vacuum or a vacuum followed by plasma. The methods are such that, upon vaporization of the source of peroxide caused by the vacuum, the peroxide remains in contact with the article for a time sufficient to achieve sterilization.