Jonathan M Driver

US Patent:

20120034162, Feb 9, 2012

Filed:

Mar 30, 2007

Appl. No.:

12/294991

Inventors:

Andrew R. Barron - Houston TX, US
Jianzhong Yang - Missouri City TX, US
Jianhua Yang - Bellaire TX, US
Kuan Wang - Heilongjiang, CN
Jonathan Driver - Katy TX, US

Assignee:

William March Rice University - Houston TX

International Classification:

A61K 51/08
C07K 19/00
C12N 5/071
A61K 38/02
A61K 38/14
A61K 9/127
C07K 2/00
C07K 1/107
B82Y 5/00

US Classification:

424 169, 530300, 530322, 530409, 435375, 530334, 514 11, 514 209, 424450, 977773, 977915, 977738

Abstract:

A composition and method is described for intracellular delivery of fullerene containing peptides. The composition and method involve fullerene-substituted phenylalanine as part of a peptide based delivery system. The presence of a fullerene-substituted amino acid in a peptide is found to alter the intracellular transport properties of the peptide.