Jonathan P Martin

US Patent:

20020070953, Jun 13, 2002

Filed:

May 4, 2001

Appl. No.:

09/848202

Inventors:

Timothy Barg - Naperville IL, US
Stephen Eick - Naperville IL, US
Jonathan Martin - Wheaton IL, US
William Swanson - Saint Charles IL, US
Ronald Smith - Batavia IL, US
Darryl Whitmore - Palatine IL, US
Kurt Rivard - Naperville IL, US

International Classification:

G09G005/00

US Classification:

345/700000

Abstract:

A tree-structured workflow control and a tree-structured report selection control allow users to easily display data and generate reports, without having to actively determine the various measures and dimensions to be displayed in various interactive views of the data and various simple and advanced reports. By linking predetermined sets of dimensions, measures and views to predetermined workflow control entries and report selection entries in a tree structure having labels on the branches and leaves that are logically related to the associated predetermined sets, the user can immediately obtain a data visualization perspective or a report without having to actively select the particular dimensions and measures for display, and without having to actively arrange the selected dimensions into a multi-dimensional view. The user can also alter the particular dimensions and/or measures being displayed and associate the user's selection with a new predetermined entry in the tree-structured workflow and report selection controls.

US Patent:

55591442, Sep 24, 1996

Filed:

May 5, 1995

Appl. No.:

8/435399

Inventors:

Dee W. Brooks - Libertyville IL
Andrew O. Stewart - Wildwood IL
Daniel J. Kerkman - Lake Villa IL
Pramila A. Bhatia - Mundelein IL
Anwer Basha - Lake Forest IL
Jonathan G. Martin - Knoxville TN

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3134
A61K 3138
C07D30746
C07D33322

US Classification:

514445

Abstract:

Compounds of the structure ##STR1## where p and q are zero or one, but cannot both be the same, M is a pharmaceutically acceptable cation or a metabolically cleavable group, B is a valence bond or a straight or branched alkylene group, R is alkyl, cycloalkyl or --NR. sup. 1 R. sup. 2, where R. sup. 1 and R. sup. 2 are hydrogen, alkyl, cycloalkyl or alkanoyl, and A is optionally substituted carbocyclic aryl, furyl, benzo[b]furyl, thienyl, or benzo[b]thienyl are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.

US Patent:

51853639, Feb 9, 1993

Filed:

Sep 30, 1991

Appl. No.:

7/768621

Inventors:

Dee W. Brooks - Libertyville IL
Daniel J. Kerkman - Lake Villa IL
Jonathan G. Martin - Waukegan IL
Andrew O. Stewart - Wildwood IL
James B. Summers - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3138
A61K33332
A61K33322

US Classification:

514438

Abstract:

Substituted phenyl, naphthyl, and thienyl N-hydroxy urea compounds form a class of potent inhibitors of 5- and 12-lipoxygenase and are thus useful compounds in the treatment of inflammatory disease states where leukotrienes and other products of lipoxygenase enzyme activity are implicated.

US Patent:

54768730, Dec 19, 1995

Filed:

Apr 19, 1994

Appl. No.:

8/229860

Inventors:

Dee W. Brooks - Libertyville IL
Andrew O. Stewart - Wildwood IL
Daniel J. Kerkman - Lake Villa IL
Pramila A. Bhatia - Mundelein IL
Anwer Basha - Lake Forest IL
Jonathan G. Martin - Knoxville TN

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07C25906
C07C27318
C07C27564
A61K 3117

US Classification:

514595

Abstract:

Compounds of the structure ##STR1## where p and q are zero or one, but cannot both be the same, M is a pharmaceutically acceptable cation or a metabolically cleavable group, B is a valence bond or a straight or branched alkylene group, R is alkyl, cycloalkyl or --NR. sup. 1 R. sup. 2, where R. sup. 1 and R. sup. 2 are hydrogen, alkyl, cycloalkyl or alkanoyl, and A is optionally substituted carbocyclic aryl, furyl, benzo[b]furyl, thienyl, or benzo[b]thienyl are potent inhibitors of lipoxygenase enzymes and thus inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states.

US Patent:

51838184, Feb 2, 1993

Filed:

Aug 27, 1991

Appl. No.:

7/750362

Inventors:

Dee W. Brooks - Libertyville IL
Andrew O. Stewart - Wildwood IL
Jonathan G. Martin - Knoxville TN

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3138
C07D33332

US Classification:

5142315

Abstract:

The present invention provides compounds having the structure Y-Het-[Q. sub. 1 ]-X-[Q. sub. 2 ]-Z which inhibit the catalytic action of lipoxygenase enzymes, particularly 5-lipoxygenase, and thereby reduce the biosynthesis of leukotrienes B. sub. 4, C. sub. 4, D. sub. 4, and E. sub. 4. In the generic formula given above, X is oxygen or sulfur and Het is a heteroaryl group selected from the group consisting of furyl, thienyl, 2-, 3-, and 4-pyridyl, 2- and 3-benzo[b]furyl, 2- and 3-benzo[b]thienyl and thienothienyl. Y is one or two substituents independently selected from hydrogen, hydroxy, halogen, cyano, alkyl, haloalkyl, alkoxy, alkylthio, alkoxyaryl), alkylthioaryl, arylalkoxy, arylalkylthio, aryloxy, arylthio, alkylamido, cycloalkyl, alkanoyl, alkoxycarbonyl, amino, alkylamino, dialkylamino, and the following groups wherein R, at each occurrence, is independently selected from hydrogen and alkyl of from one to six carbon atoms: --CRROR, --NRC(O)R, --NRC(O)OR, and --C(O)NRR. The group Q. sub. 1 is absent or is divalent alkylene of from one to six carbon atoms, and Q. sub.