Jonathan D Root

US Patent:

6551268, Apr 22, 2003

Filed:

Apr 14, 2000

Appl. No.:

09/550356

Inventors:

Alan L. Kaganov - Portola Valley CA
Jonathan D. Root - San Francisco CA
John McKenzie - San Carlos CA

Assignee:

Embol-X, Inc. - Mountain View CA

International Classification:

A61M 500

US Classification:

604 8, 604200, 604159

Abstract:

A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes a first tubular member having a proximal end, a distal end, and a lumen therebetween. The proximal end has an opening in communication with the lumen, and the proximal opening is adapted to receive blood from a first region of an artery. The distal end has an opening in communication with the lumen, and the distal opening is adapted to release blood into a second region of the artery. The shunt includes a second tubular member having a proximal end, a distal end, and a lumen therebetween which either merges and communicates at its distal end with the lumen of the first tubular member, or rides separate and parallel to it. The shunt also includes a hemostatic valve attached to the proximal end of the second tubular member, the valve acting to prevent loss of blood from the lumen of the second tubular member and to permit the introduction of a medical device into the lumen of the second tubular member and into the artery. In use, the distal opening of the shunt is inserted into the second region of an artery and secured to the lumen of the artery.

US Patent:

6592546, Jul 15, 2003

Filed:

Jan 30, 1998

Appl. No.:

09/016714

Inventors:

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA
Tracy D. Maahs - Redwood City CA
Ross S. Tsugita - Mountain View CA

Assignee:

Edwards Lifesciences Corp. - Irvine CA

International Classification:

A61M 2900

US Classification:

604 9601, 604104, 606200

Abstract:

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

US Patent:

6673090, Jan 6, 2004

Filed:

Jan 22, 2001

Appl. No.:

09/766940

Inventors:

Jonathan D. Root - San Francisco CA
Kevin Hahnen - Sarasota FL
Tracy D. Maahs - Santa Clara CA

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2900

US Classification:

606200

Abstract:

An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedures are disclosed.

US Patent:

6682543, Jan 27, 2004

Filed:

Oct 24, 2001

Appl. No.:

10/055216

Inventors:

Denise R. Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA

Assignee:

C Edwards Lifesciences Corporation - Irvine CA

International Classification:

A61B 1722

US Classification:

606159

Abstract:

A method for removing plaque from the aorta is disclosed. A filter is introduced into a region of interest within the patients aorta. The filter is deployed downstream of a mobile aortic plaque within the aorta. An atherectomy assembly is operated to excise the plaque from the aorta. Emboli are captured by the filter. The filter and plaque are removed from the region of interest.

US Patent:

6689084, Feb 10, 2004

Filed:

Feb 12, 2003

Appl. No.:

10/366117

Inventors:

Alan L. Kaganov - Portola Valley CA
Jonathan D. Root - San Francisco CA
John McKenzie - San Carlos CA

Assignee:

Edwards Lifescience Corporation - Irvine CA

International Classification:

A61M 500

US Classification:

604 8, 600200, 600159

Abstract:

A method for carotid endarterectomy. A blood filter is positioned within a carotid artery downstream of an atheromatous plaque. The filter is expanded. The carotid artery is clamped upstream and downstream of the atheromatous plaque while the filter is expanded. An endarterectomy procedure is performed on the region of the carotid artery having the atheromatous plaque. The carotid artery is unclamped while the filter is expanded. In certain cases a shunt is positioned in a region of the carotid artery having the atheromatous plaque and secured to the shunt by clamping, the shunt comprising a tubular member having a proximal opening, a distal opening, and a lumen therebetween.

US Patent:

7306575, Dec 11, 2007

Filed:

Jul 14, 2003

Appl. No.:

10/619760

Inventors:

Denise Barbut - New York NY, US
Jonathan D. Root - San Francisco CA, US
Giovanni Pastrone - Los Gatos CA, US
Tracy D. Maahs - Redwood City CA, US
Ross S. Tsugita - Mountain View CA, US

Assignee:

Edwards Lifesciences Corporation - Irvine CA

International Classification:

A61M 29/00

US Classification:

604 9601, 604104, 606200

Abstract:

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

US Patent:

7326226, Feb 5, 2008

Filed:

Nov 3, 2003

Appl. No.:

10/699727

Inventors:

Jonathan D. Root - San Francisco CA, US
Kevin Hahnen - Sarasota FL, US
Tracy D. Maahs - Santa Clara CA, US

Assignee:

Boston Scientific Scimed, Inc. - Maple Grove MN

International Classification:

A61M 29/00

US Classification:

606200

Abstract:

An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedures are disclosed.

US Patent:

20080065008, Mar 13, 2008

Filed:

Nov 16, 2007

Appl. No.:

11/941872

Inventors:

Denise Barbut - New York NY, US
Jonathan Root - San Francisco CA, US
Giovanni Pastrone - Los Gatos CA, US
Tracy Maahs - Redwood City CA, US
Ross Tsugita - Mountain View CA, US

International Classification:

A61M 25/10

US Classification:

604096010

Abstract:

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.