Jonathan D Root

US Patent:

6592546, Jul 15, 2003

Filed:

Jan 30, 1998

Appl. No.:

09/016714

Inventors:

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA
Tracy D. Maahs - Redwood City CA
Ross S. Tsugita - Mountain View CA

Assignee:

Edwards Lifesciences Corp. - Irvine CA

International Classification:

A61M 2900

US Classification:

604 9601, 604104, 606200

Abstract:

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

US Patent:

6682543, Jan 27, 2004

Filed:

Oct 24, 2001

Appl. No.:

10/055216

Inventors:

Denise R. Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA

Assignee:

C Edwards Lifesciences Corporation - Irvine CA

International Classification:

A61B 1722

US Classification:

606159

Abstract:

A method for removing plaque from the aorta is disclosed. A filter is introduced into a region of interest within the patients aorta. The filter is deployed downstream of a mobile aortic plaque within the aorta. An atherectomy assembly is operated to excise the plaque from the aorta. Emboli are captured by the filter. The filter and plaque are removed from the region of interest.

US Patent:

7306575, Dec 11, 2007

Filed:

Jul 14, 2003

Appl. No.:

10/619760

Inventors:

Denise Barbut - New York NY, US
Jonathan D. Root - San Francisco CA, US
Giovanni Pastrone - Los Gatos CA, US
Tracy D. Maahs - Redwood City CA, US
Ross S. Tsugita - Mountain View CA, US

Assignee:

Edwards Lifesciences Corporation - Irvine CA

International Classification:

A61M 29/00

US Classification:

604 9601, 604104, 606200

Abstract:

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

US Patent:

20080065008, Mar 13, 2008

Filed:

Nov 16, 2007

Appl. No.:

11/941872

Inventors:

Denise Barbut - New York NY, US
Jonathan Root - San Francisco CA, US
Giovanni Pastrone - Los Gatos CA, US
Tracy Maahs - Redwood City CA, US
Ross Tsugita - Mountain View CA, US

International Classification:

A61M 25/10

US Classification:

604096010

Abstract:

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

US Patent:

56626711, Sep 2, 1997

Filed:

Jul 17, 1996

Appl. No.:

8/683503

Inventors:

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA
Robert Rizzari - Haverhill MA
James M. Sellers - Hampstead NH
Giovanni Pastrone - Los Gatos CA
John McKenzie - San Carlos CA

Assignee:

Embol-X, Inc. - Portola Valley CA

International Classification:

A61M 2500

US Classification:

606170

Abstract:

An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.

US Patent:

63093995, Oct 30, 2001

Filed:

Sep 7, 2000

Appl. No.:

9/656775

Inventors:

Denise R. Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2900

US Classification:

606159

Abstract:

An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.

US Patent:

57698163, Jun 23, 1998

Filed:

Apr 30, 1996

Appl. No.:

8/640015

Inventors:

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA
James M. Sellers - Hampstead NH
Robert Rizzari - Haverhill MA

Assignee:

Embol-X, Inc. - Portola Valley CA

International Classification:

A61M 2900

US Classification:

604 96

Abstract:

Devices and methods for filtering blood. The devices generally comprise: a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta; a structure adapted to open and close the mesh within the blood vessel; and a means to actuate the structure. The methods generally include the following steps: introducing a mesh into a blood vessel to entrap embolic material; adjusting the mesh, if necessary, during the course of filtration; and removing the mesh and the entrapped foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

US Patent:

61360163, Oct 24, 2000

Filed:

Jul 12, 1999

Appl. No.:

9/352546

Inventors:

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA

Assignee:

Embol-X, Inc. - Mountain View CA

International Classification:

A61B 2900

US Classification:

606200

Abstract:

Devices and methods for filtering blood. The devices generally comprise: a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta; a structure adapted to open and close the mesh within the blood vessel; and a means to actuate the structure. The methods generally include the following steps: introducing a mesh into a blood vessel to entrap embolic material; adjusting the mesh, if necessary, during the course of filtration; and removing the mesh and the entrapped foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.