This invention relates to novel mammalian multipotent neural stem cells (MNSCs), compositions thereof, and methods of preparing and administering the cells to diseased, aged or damaged tissue such that the cells properly migrate and differentiate and a neurological or corporal deficit is improved or remedied as a result.
Mammalian Multipotent Stem Cells And Compositions, Methods Of Preparation And Methods Of Administration Thereof
Kiminobu Sugaya - Willow Springs IL, US Tingyu Qu - Chicago IL, US Ankur V. Vaghani - Chicago IL, US Christopher Brannen - Vancouver WA, US Hojoong M. Kim - Chicago IL, US Jose S. Pulido - Brookfield WI, US Xiajing Dong - Oak Park IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells.
Silencing Of Tgfβ Type Ii Receptor Expression By Sirna
Nalin M. Kumar - Wilmette IL, US Beatrice Yue - Deerfield IL, US Shahid Siddiqui - Wilmette IL, US Asrar B. Malik - Hinsdale IL, US Jose S. Pulido - Rochester MN, US
Assignee:
The Broad of Trustees of the University of Illinois - Chicago IL
The present application is directed to siRNA-based silencing of the type II receptor of TGFβ. siRNAs that target this receptor abrogate the receptor protein and transcript, TGFβ-mediated processes such as fibronectin assembly and cell migration also are inhibited and the molecules of the invention are efficacious in reducing the inflammatory response and matrix deposition. These findings show that siRNAs can be successfully delivered both in vitro and in vivo to regulate the TGFβ type II receptor level and modulate wound response. Methods and compositions exploiting the findings of the present invention have a wide-ranging application, extending from treatment of disorders of the eye to other organs and tissues throughout the body.
Mammalian Multipotent Stem Cells And Compositions, Methods Of Preparation And Methods Of Administration Thereof
Kiminobu Sugaya - Willow Springs IL, US Tingyu Qu - Chicago IL, US Ankur V. Vaghani - Chicago IL, US Christopher Brannen - Vancouver WA, US Hojoong M. Kim - Chicago IL, US Jose S. Pulido - Brookfield WI, US Xiajing Dong - Oak Park IL, US
Assignee:
University of Central Florida Research Foundation, Inc. - Orlando FL
This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells.
Silencing Of Tgf-Beta Receptor Type Ii Expression By Sirna
Nalin Kumar - Wilmette IL, US Beatrice Yue - Deerfield IL, US Shahid Siddiqui - Wilmette IL, US Asrar Malik - Hinsdale IL, US Jose Pulido - Brookfield WI, US
International Classification:
A61K 48/00 C07H 21/02
US Classification:
514044000, 536023100
Abstract:
The present application is directed to siRNA-based silencing of the type II receptor of TGFβ. siRNAs that target this receptor abrogate the receptor protein and transcript, TGFβ-mediated processes such as fibronectin assembly and cell migration also are inhibited and the molecules of the invention are efficacious in reducing the inflammatory response and matrix deposition. These findings show that siRNAs can be successfully delivered both in vitro and in vivo to regulate the TGFβ type II receptor level and modulate wound response. Methods and compositions exploiting the findings of the present invention have a wide-ranging application, extending from treatment of disorders of the eye to other organs and tissues throughout the body.
Richard G. Vile - Rochester MN, US Timothy J. Kottke - Oronoco MN, US Jose S. Pulido - Rochester MN, US Jill M. Thompson - Stewartville MN, US Alan Melcher - Leeds, GB
International Classification:
A61K 31/7088 C07H 21/04 C12N 15/63 A61P 35/00
US Classification:
514 44 R, 536 235, 536 232, 4353201
Abstract:
This document provides methods and materials related to treating cancer. For example, methods and materials that include using CD40L polypeptide, an hsp70 polypeptide, and a cytotoxic polypeptide to trigger an immune response directed against cancer cells are provided.
Richard G. Vile - Rochester MN, US Timothy J. Kottke - Oronoco MN, US Jose S. Pulido - Rochester MN, US Alan Melcher - Leeds, GB Peter Selby - Leeds, GB
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
This document provides methods and materials related to treating cancer. For example, methods and materials for using nucleic acid libraries to treat cancer are provided.
Novel Mammalian Multipotent Stem Cells And Compositions, Methods Of Preparation And Methods Of Administration Thereof
Tingyu Qu - Chicago IL, US Ankur V. Vaghani - Chicago IL, US Christopher Brannen - Vancouver WA, US Hojoong M. Kim - Chicago IL, US Jose S. Pulido - Brookfield WI, US Xiajing Dong - Oak Park IL, US
This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells.
Name / Title
Company / Classification
Phones & Addresses
Jose Pulido Owner
Gabriel Export Corp Motor Vehicle Parts and Accessories
Aug 2011 to 2000 Logistics Team LeaderTarget Chicago, IL Sep 2010 to Aug 2011 Perishable AssistantTarget Chicago, IL Oct 2009 to Sep 2010 Backroom Team Member
Education:
HAROLD WASHINGTON COLLEGE Chicago, IL Jun 2014 Computer science
Skills:
Fluent in both English and Spanish, Inventory managemment,repairing and trouble shooting of computer hardware, software, and printers
Mayo Clinic 200 1St St Sw, Rochester, MN 55905 5072842511 (Phone)
Certifications:
Ophthalmology, 1986
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School Tulane University School Of Medicine Graduated: 1981 Medical School Charity Hospital Graduated: 1982 Medical School University Ill Ee Infirm Graduated: 1986 Medical School University Ill Eye/Ear Infmry Graduated: 1985 Medical School Bascom Palmer Eye Institute Graduated: 1987
Mayo ClinicMayo Clinic Rochester Ophthalmology 200 1 St SW, Rochester, MN 55905 5072842744 (phone), 5072844612 (fax)
Education:
Medical School Tulane University School of Medicine Graduated: 1981
Procedures:
Destruction of Lesion of Retina and Choroid Retinal Detachment Repair Eye Muscle Surgery Eyeglass Fitting Lens and Cataract Procedures Ophthalmological Exam
Dr. Pulido graduated from the Tulane University School of Medicine in 1981. He works in Rochester, MN and specializes in Ophthalmology. Dr. Pulido is affiliated with Mayo Clinic Hospital-Rochester Methodist Campus and Saint Marys Hospital.
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