Jose L Rosa

US Patent:

7300646, Nov 27, 2007

Filed:

Feb 27, 2004

Appl. No.:

10/789293

Inventors:

Jose Rosa - Edgewater NJ, US
Michael James Barratt - Oak Ridge NJ, US
Carol Annette Bosko - Oradell NJ, US
John Steven Bajor - Ramsey NJ, US

Assignee:

Unilever Home & Personal Care USA, division of Conopco, Inc. - Greenwich CT

International Classification:

A61Q 19/02
A61Q 19/04
A61K 8/02
A61K 31/235

US Classification:

424 62, 424 59, 424 60, 424400, 424401, 514543, 514544

Abstract:

Disclosed are coumarin derived compounds of formula I as skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle:Also disclosed are processes for making the inventive compounds of general formula I from 4-substituted-7-hydroxy coumarin derivatives.

US Patent:

7524485, Apr 28, 2009

Filed:

Nov 21, 2003

Appl. No.:

10/718988

Inventors:

Michael James Barratt - Oak Ridge NJ, US
Carol Annette Bosko - Oradell NJ, US
Victor De Florio - Cranford NJ, US
Jose Guillermo Rosa - Edgewater NJ, US
Michael Tallman - Park Ridge NJ, US

Assignee:

Unilever Home & Personal Care, USA, Division of Conopco, Inc. - Greenwich CT

International Classification:

A61K 8/18
A61Q 17/04
A61K 8/00
A61Q 5/00
A61Q 9/00
A61K 8/02

US Classification:

424 59, 424 60, 424 701, 424400, 424401

Abstract:

Compounds of formula I, process for making same, and cosmetic compositions and methods of skin lightening using compounds of formula I as skin lightening agents:.

US Patent:

20040228831, Nov 18, 2004

Filed:

May 15, 2003

Appl. No.:

10/437983

Inventors:

Benjamin Belinka - Kendall Park NJ, US
James Pachence - Hopewell NJ, US
Jose Rosa - Lawrenceville NJ, US
Paul Simon - Wilmington DE, US

International Classification:

A61K038/43

US Classification:

424/078270, 424/094100

Abstract:

The present invention relates to a polymeric drug conjugate with one or more biologically active agents conjugated via an enzymatically cleavable linker to either a regular repeating linear unit comprising a water soluble polymer segment and a multifunctional chemical moiety, or a branched polymer comprising two or more water soluble polymer segments each bound to a common multifunctional chemical moiety, as well as to methods of making such conjugates. The present invention is also directed to pharmaceutical compositions comprising such conjugates and to the use of such conjugates to treat pathological conditions.

US Patent:

20060047168, Mar 2, 2006

Filed:

Aug 25, 2004

Appl. No.:

10/926222

Inventors:

Jose Rosa - Edgewater NJ, US
Victor De Florio - Cranford NJ, US

International Classification:

C07C 62/08

US Classification:

562579000

Abstract:

Process for carboxy-alkylation, particularly carboxymethylation, of branched alcohols includes the reaction of isoalcohols with potassium-t-butoxide or sodium-t-butoxide and with salt of halogenated alkanoic acid in the presence of the isoalcohol (starting alcohol) as the solvent. Produced are isoalcohol carboxy-alkylates (preferably, carboxymethylates) in excellent yields and purity.

US Patent:

20060210497, Sep 21, 2006

Filed:

Mar 18, 2005

Appl. No.:

11/083626

Inventors:

Jose Rosa - Edgewater NJ, US
John Bajor - Cheshire CT, US

International Classification:

C07C 39/12
A61K 8/34

US Classification:

424062000, 568731000

Abstract:

New 4-substituted resorcinol derivatives of general formula I and/or B and process for synthesizing same, cosmetic compositions and methods of using same, particularly for skin lightening and/or reducing the appearance of oily or greasy skin: Wherein

US Patent:

20060210498, Sep 21, 2006

Filed:

Mar 18, 2005

Appl. No.:

11/084601

Inventors:

Jose Rosa - Edgewater NJ, US

International Classification:

A61K 8/34
C07C 39/12

US Classification:

424062000, 568731000

Abstract:

New 4-substituted resorcinol derivatives of general formula I and/or B and process for synthesizing same, cosmetic compositions and methods of using same, particularly for skin lightening: Wherein