Joseph P Duffy

US Patent:

52458970, Sep 21, 1993

Filed:

Nov 25, 1991

Appl. No.:

7/797324

Inventors:

Paul J. Arnold - Bear DE
Robert L. Brown - Wilmington DE
Joseph J. Duffy - Newark DE
Pui-Yan Lin - Hockessin DE
Robert A. Marin - Hockessin DE

Assignee:

E. I. Du Pont de Nemours and Company - Wilmington DE

International Classification:

B26D 706
B65G 1522
B65G 1558

US Classification:

83 56

Abstract:

The present invention is directed to an apparatus for advancing the leading edge of a corrugated web for positioning the web for a secondary operation, such as a cutting operation to cut a discrete sheet from the web. The web has a plurality of alternating peaks and valleys. The apparatus comprises an endless loop conveyor including a plurality of spaced support bars for contacting the valleys of the web. At least one vacuum source holds the web against the support bars. A motor and a distributed control system repeatedly advance the conveyor and the leading edge of the web from the entrance end to the exit end of the conveyor. A rotary encoder and a sensor sense the presence of a support bar near the position for applying the cutting operation. The vacuum source is de-activated, and at least one pressure source is activated to remove the cut sheet from the support bars. The de-activation of the vacuum source and the activation of the pressure source are done progressively from one end of the conveyor to the other to progressively remove the cut sheet from the conveyor.

US Patent:

20190337910, Nov 7, 2019

Filed:

Mar 20, 2017

Appl. No.:

16/087382

Inventors:

- RAHWAY NJ, US
BRIAN T. CAMPBELL - BENSALEM PA, US
JOSEPH L. DUFFY - CRANFORD NJ, US
THOMAS J. GRESHOCK - COLLEGEVILLE PA, US
DEODIAL G. GUIADEEN - CHESTERFIELD NJ, US
ANDREW JOHN HARVEY - PADDINGTON, AU
BELINDA C. HUFF - THEBARTON SA, AU
KENNETH J. LEAVITT - MOUNT LAUREL NJ, US
VANESSA L. RADA - HATFIELD PA, US
JOHN M. SANDERS - HATFIELD PA, US
WILLIAM D. SHIPE - CHALFONT PA, US
LINDA M. SUEN - PHILADELPHIA PA, US
IAN M. BELL - HARLEYSVILLE PA, US

Assignee:

MERCK SHARP & DOHME CORP. - RAHWAY NJ

International Classification:

C07D 285/12
C07D 231/12
C07D 233/64
C07D 249/06
C07D 249/08
C07D 261/08
C07D 263/32
C07D 271/06
C07D 277/26
C07D 285/08
C07D 413/04
C07D 413/06
C07D 413/10
C07D 417/04

Abstract:

The present disclosure relates to compounds of formula (I) that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation.

US Patent:

20180030007, Feb 1, 2018

Filed:

Oct 9, 2017

Appl. No.:

15/727982

Inventors:

- Rahway NJ, US
Brian T. Campbell - Bensalem PA, US
Joseph L. Duffy - Cranford NJ, US
Thomas J. Greshock - Collegeville PA, US
Deodial G. Guiadeen - Chesterfield NJ, US
Andrew John Harvey - Paddington, AU
Belinda C. Huff - Thebarton SA, AU
Kenneth J. Leavitt - Mount Laurel NJ, US
Vanessa L. Rada - West Point PA, US
John M. Sanders - Hatfield PA, US
William D. Shipe - Chalfont PA, US
Linda M. Suen - West Point PA, US
Ian M. Bell - Harleysville PA, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

C07D 285/12
A61K 31/415
C07D 271/107
C07D 271/06
C07D 263/32
C07D 261/08
C07D 249/04
C07D 231/12
A61K 31/433
A61K 31/426
A61K 31/4245
A61K 31/421
A61K 31/42
A61K 31/4192
C07D 277/26
C07D 285/08

Abstract:

The present disclosure relates to compounds of formula I that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation

US Patent:

20170275260, Sep 28, 2017

Filed:

Mar 20, 2017

Appl. No.:

15/463336

Inventors:

- RAHWAY NJ, US
BRIAN T. CAMPBELL - BENSALEM PA, US
JOSEPH L. DUFFY - CRANFORD NJ, US
THOMAS J. GRESHOCK - COLLEGEVILLE PA, US
DEODIAL G. GUIADEEN - CHESTERFIELD NJ, US
ANDREW JOHN HARVEY - PADDINGTON, AU
BELINDA C. HUFF - THEBARTON SA, AU
KENNETH J. LEAVITT - MOUNT LAUREL NJ, US
VANESSA L. RADA - HATFIELD PA, US
JOHN M. SANDERS - HATFIELD PA, US
WILLIAM D. SHIPE - CHALFONT PA, US
LINDA M. SUEN - PHILADELPHIA PA, US
IAN M. BELL - HARLEYSVILLE PA, US

Assignee:

MERCK SHARP & DOHME CORP. - RAHWAY NJ

International Classification:

C07D 285/12
A61K 31/4245
A61K 31/433
C07D 271/107
C07D 263/32
A61K 31/421
C07D 261/08
A61K 31/42
C07D 249/04
A61K 31/4192
C07D 231/12
A61K 31/415
C07D 277/26
A61K 31/426
C07D 285/08
C07D 271/06

Abstract:

The present disclosure relates to compounds of formula I that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation