Joseph D Greco

US Patent:

20110008458, Jan 13, 2011

Filed:

Jul 9, 2009

Appl. No.:

12/459911

Inventors:

James Gandy - Calhoun LA, US
Robert J. Brandt - Ft. Myers FL, US
Ryan N. Brandt - Cape Coral FL, US
Clark Galen - Osprey FL, US
Joseph Greco - Sarasota FL, US
John Kiwczak - Sarasota FL, US

International Classification:

A61K 35/16
C07K 1/14
A61K 38/18
A61P 17/02

US Classification:

424530, 530412, 514 82, 514 94

Abstract:

A sub-atmospheric, negative pressure is applied to a growth factor starting material, such as whole blood, to release growth factors and plasma in a non-destructive medium. The released growth factors having a weight of about 70-76 kDaltons are applied in either a filtered or unfiltered state to a wound to promote healing of the wound. The released growth factors are applied topically to the area of a surface wound to effect healing. The released growth factors are also injected into soft tissue, such as a torn tendon, to promote tissue growth and healing. The growth factors are released in one method from a patient's own blood. In another method the growth factors are released from a whole blood source and freeze dried by conventional lyophilization. Then at a later date, the freeze dried product is reconstituted by normal saline for treatment of a patient's wound or for use in a surgical procedure.