Joseph A Hammer

US Patent:

7192604, Mar 20, 2007

Filed:

Dec 7, 2001

Appl. No.:

10/020021

Inventors:

Kelly R. Brown - Hillsborough NJ, US
Iksoo Chun - Flemington NJ, US
Joseph J. Hammer - Bridgewater NJ, US
Victor F. Janas - Monroe Township NJ, US
Jennifer Mandanas - Painted Post NY, US
Mora C Melican - Bridgewater NJ, US
Alireza Rezania - Hillsborough NJ, US
Mark C. Zimmerman - East Brunswick NJ, US

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

A61K 9/70
A61L 15/64

US Classification:

424422, 424423, 424400, 424443

Abstract:

An implantable biodegradable device is disclosed containing a fibrous matrix, the fibrous matrix being constructed from fibers A and fibers B, wherein fibers A biodegrade faster than fibers B, fibers A and fibers B are present in relative amounts and are organized such that the fibrous matrix is provided with properties useful in repair and/or regeneration of mammalian tissue.

US Patent:

8110210, Feb 7, 2012

Filed:

Apr 20, 2004

Appl. No.:

10/828838

Inventors:

Stephanie M. Kladakis - Watertown MA, US
Joseph J. Hammer - Bridgewater NJ, US
Dhanuraj Shetty - Somerset NJ, US
Sridevi Dhanaraj - Raritan NJ, US

Assignee:

DePuy Mitek, Inc. - Raynham MA

International Classification:

A61F 2/00

US Classification:

424423, 424426

Abstract:

A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.

US Patent:

8137686, Mar 20, 2012

Filed:

Apr 20, 2004

Appl. No.:

10/828838

Inventors:

Stephanie M. Kladakis - Watertown MA, US
Joseph J. Hammer - Bridgewater NJ, US
Dhanuraj Shetty - Somerset NJ, US
Sridevi Dhanaraj - Raritan NJ, US

Assignee:

DePuy Mitek, Inc. - Raynham MA

International Classification:

A61F 2/00

US Classification:

424423, 424426

Abstract:

A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.

US Patent:

8226715, Jul 24, 2012

Filed:

Jun 30, 2003

Appl. No.:

10/610362

Inventors:

Julia Hwang - Wayland MA, US
Joseph Hammer - Bridgewater NJ, US
Herb Schwartz - Fort Wayne IN, US
Prasanna Malaviya - Fort Wayne IN, US

Assignee:

DePuy Mitek, Inc. - Raynham MA

International Classification:

A61F 2/08

US Classification:

623 1314, 623 1318

Abstract:

A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.

US Patent:

20020119179, Aug 29, 2002

Filed:

Dec 22, 2000

Appl. No.:

09/745783

Inventors:

Alireza Rezania - Hillsborough NJ, US
Joseph Hammer - Bridgewater NJ, US
Iksoo Chun - Flemington NJ, US
Mark Zimmerman - East Brunswick NJ, US
Mora Melican - Bridgewater NJ, US

International Classification:

A61K009/14

US Classification:

424/426000, 442/123000

Abstract:

An implantable biodegradable device is disclosed containing a fibrous matrix, the fibrous matrix being constructed from fibers A and fibers B, wherein fibers A biodegrade faster than fibers B, fibers A and fibers B are present in relative amounts and are organized such that the fibrous matrix is provided with properties useful in repair and/or regeneration of mammalian tissue.

US Patent:

20060286171, Dec 21, 2006

Filed:

Jun 17, 2005

Appl. No.:

11/156153

Inventors:

Tianhong Zhou - Basking Ridge NJ, US
Chunlin Yang - Belle Mead NJ, US
Jeffery Geesin - Doylestown PA, US
Aruna Nathan - Bridgewater NJ, US
Joseph Hammer - Hillsborough NJ, US

International Classification:

A61K 38/17
A61K 31/724
A61K 31/4172
A61K 31/198

US Classification:

424486000, 514012000, 514058000, 514400000, 514562000

Abstract:

Protein formulations that can be lyophilized and are stable in organic solvents. The formulations contain bone morphogenetic proteins, lyoprotectants, and oxidation/reduction stabilizers. Optionally, the formulations may also contain solvent environment stabilizers. The protein formulations can be incorporated into a polymeric matrix to make medical devices for delivering the protein, and coatings for medical devices.

US Patent:

20060286289, Dec 21, 2006

Filed:

Jun 15, 2005

Appl. No.:

11/153285

Inventors:

Rita Prajapati - Quincy MA, US
Steven Bowman - Sherborn MA, US
Mark Timmer - Jersey City NJ, US
Patrick De Deyne - Duxbury MA, US
Joseph Hammer - Hillsborough NJ, US
Chunlin Yang - Belle Mead NJ, US

International Classification:

A61F 13/02

US Classification:

427002310

Abstract:

Intra-operative coating of sutures with therapeutic proteins, particularly growth factors such as rhGDF-5. including contacting a suture to a device containing a therapeutic agent.

US Patent:

20060287675, Dec 21, 2006

Filed:

Dec 22, 2005

Appl. No.:

11/315793

Inventors:

Rita Prajapati - Quincy MA, US
Steven Bowman - Sherbom MA, US
Mark Timmer - Jersey City NJ, US
Patrick De Dyne - Duxbury MA, US
Joseph Hammer - Hillsborough NJ, US
Chunlin Yang - Belle Meade NJ, US

International Classification:

A61L 17/00

US Classification:

606228000

Abstract:

Intra-operative coating of sutures with therapeutic proteins, particularly growth factors such as rhGDF-5. including contacting a suture to a device containing a therapeutic agent, methods of repairing soft tissue defects with coated sutures and composite sutures coated with therapeutic agents.