Timothy Guzi - Chatham NJ Dinanath F. Rane - Morganville NJ Alan K. Mallams - Hackettstown NJ Alan B. Cooper - West Caldwell NJ Ronald J. Doll - Maplewood NJ Viyyoor M. Girijavallabhan - Parsippany NJ Arthur G. Taveras - Denville NJ Corey Strickland - North Plainfield NJ Joseph M. Kelly - Parlin NJ Jianping Chao - Summit NJ
Disclosed are compounds of the formula: wherein R represents a cyclic moiety to which is bound an imodazolylalkyl group; R represents a carbamate, urea, amide or sulfonamide group; and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.
Arthur G. Taveras - Denville NJ Ronald J. Doll - Maplewood NJ Alan B. Cooper - West Caldwell NJ Johan A. Ferreira - Bensalem PA Timothy Guzi - Chatham NJ Dinanath F. Rane - Morganville NJ Viyyoor M. Girijavallabhan - Parsippany NJ Cynthia J. Aki - Rutherford NJ Jianping Chao - Summit NJ Carmen Alvarez - Roselle Park NJ Joseph M. Kelly - Parlin NJ Tarik Lalwani - Philadelphia PA Jagdish A. Desai - Spotswood NJ James J-S Wang - Westfield NJ
Disclosed are compounds of the formula: wherein R represents an imidazole ring; R represents a carbamate, urea, amide or sulfonamide group; R represents H when the alkyl chain between the amide group and the R imidazole group is substituted, or R represents a substituent such as arylalkyl, heteroarylalkyl or cycloalkyl; and the remaining substituents are as defined herein. Also disclosed are compounds wherein R is H, and the alkyl chain between the amide group and the R imidazole group is unsubstituted. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.
Phenyl-Substituted Tricyclic Inhibitors Of Farnesyl-Protein Transferase
Adriano Afonso - West Caldwell NJ Joseph M. Kelly - Parlin NJ Jay Weinstein - Upper Montclair NJ Ronald L. Wolin - Bedminister NJ Stuart B. Rosenblum - West Orange NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 31496
US Classification:
514290, 544361, 546 93
Abstract:
Novel phenyl-substituted tricyclic compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel halo-N-substituted urea compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.
Compounds For The Inhibition Of Farnesyl Protein Transferase
Ronald J. Doll - Maplewood NJ Joseph M. Kelly - Parlin NJ Alan K. Mallams - Hackettstown NJ F. George Njoroge - Union NJ Stacy W. Remiszewski - Washington Township NJ Arthur G. Taveras - Rockaway NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 3144
US Classification:
514290, 546 93, 544361
Abstract:
Novel compounds, such as: are disclosed. Also disclosed are methods for inhibiting the abnormal growth of cells, for inhibiting farnesyl protein transferase and for treating cancers using the novel compounds.
Arthur G. Taveras - Denville NJ Ronald J. Doll - Maplewood NJ Alan B. Cooper - West Caldwell NJ Johan A. Ferreira - Bensalem PA Timothy Guzi - Chatham NJ Alan K. Mallams - Hackettstown NJ Dinanath F. Rane - Morganville NJ Viyyoor M. Girijavallabhan - Parsippany NJ Adriano Afonso - West Caldwell NJ Cynthia J. Aki - Rutherford NJ Jianping Chao - Summit NJ Carmen Alvarez - Roselle Park NJ Joseph M. Kelly - Parlin NJ Tarik Lalwani - Philadelphia PA Jagdish A. Desai - Spotswood NJ James J-S Wang - Westfield NJ Jay Weinstein - Upper Montclair NJ
Disclosed are compounds of the formula: wherein R represents an imidazole ring; R represents a carbamate, urea, amide or sulfonamide group; R represents H when the alkyl chain between the amide group and the R imidazole group is substituted, or R represents a substituent such as arylalkyl, heteroarylalkyl or cycloalkyl; and the remaining substituents are as defined herein. Also disclosed are compounds wherein R is H, and the alkyl chain between the amide group and the R imidazole group is unsubstituted. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.
Timothy Guzi - Chatham NJ Dinanath F. Rane - Morganville NJ Alan K. Mallams - Hackettstown NJ Alan B. Cooper - West Caldwell NJ Ronald J. Doll - Maplewood NJ Viyyoor M. Girijavallabhan - Parsippany NJ Arthur G. Taveras - Denville NJ Corey Strickland - North Plainfield NJ Joseph M. Kelly - Parlin NJ Jianping Chao - Summit NJ
Disclosed are compounds of the formula: wherein R represents a cyclic moiety to which is bound an imodazolylalkyl group; R represents a carbamate, urea, amide or sulfonamide group; and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.
Substituted Urea Neuropeptide Y Y5 Receptor Antagonists
William J. Greenlee - Teaneck NJ, US Ying Huang - East Brunswick NJ, US Joseph M. Kelly - Parlin NJ, US Stuart W. McCombie - Caldwell NJ, US Andrew W. Stamford - Chatham Township NJ, US Yusheng Wu - New York NY, US
A novel class of compounds such as antagonists of the neuropeptide Y Y5 receptor, methods of making such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention or amelioration of one or more diseases associated with the neuropeptide Y Y5 receptor are disclosed.
Bipiperdine Derivatives Useful As Ccr3 Antagonists
Pauline C. Ting - New Providence NJ, US Jianhua Cao - Edison NJ, US Youhao Dong - Edison NJ, US Eric J. Gilbert - Scotch Plains NJ, US Ying Huang - Berkeley Heights NJ, US Joseph M. Kelly - Parlin NJ, US Stuart McCombie - Caldwell NJ, US Neng-Yang Shih - Warren NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 31/4709 A61K 31/4725 C07D 215/14
US Classification:
546168, 546146, 514307, 514314
Abstract:
The use of CCR3 antagonists of the formula I.
Name / Title
Company / Classification
Phones & Addresses
Joseph Kelly Owner
Kelly & CO Accounting, Auditing, and Bookkeeping Services
2005 to 2013 Director of Wealth Management and Branch ManagerUNITED STATES NAVY
Apr 2005 to Apr 2005 Retired, United States Navy Lieutenant Commander and Supply Corps OfficerTIAA-CREF New York, NY 2002 to 2004 Consulting OfficerTIAA-CREF
1995 to 2002 Individual Consultant
Education:
American College Bryn Mawr, PA Jul 2001 Master of Science in Financial ServicesSt. John's University Jamaica, NY Sep 1986 Bachelor of Science in Finance
2012 to 2000 Senior Director, Security ServicesAMTRAK/NATIONAL RAILROAD PASSENGER CORPORATION New York, NY 2005 to 2012 Senior Director, Corporate SecurityMTA BRIDGES AND TUNNELS New York, NY 2003 to 2005 Security Manager, Internal Security DepartmentTHE JEWISH COMMUNITY CENTER IN MANHATTAN New York, NY 2001 to 2003 Director of SecurityNEW YORK CITY POLICE DEPARTMENT, New York, NY New York, NY 1982 to 2001 Commanding Officer of the 47th Precinct Robbery Apprehension Module
Education:
Criminal Justice STATE UNIVERSITY OF NEW YORK, EMPIRE STATE COLLEGE New York, NY 1993 BS in Community and Human ServicesSTATE UNIVERSITY OF NEW YORK, ORANGE COUNTY COMMUNITY COLLEGE New York, NY 1980 AAS
New York Civil Court Consumer Law Clinic Brooklyn, NY Mar 2013 to May 2013 Debtor Defense InternProfessors Bradley Borden & David Reiss Brooklyn, NY Mar 2013 to May 2013 Research AssistantHon. Carla E. Craig Brooklyn, NY Sep 2012 to Nov 2012 Chief Judge, U.S. Bankruptcy Court, E.D.N.YHon. Carla E. Craig New York, NY Sep 2012 to Nov 2012 Consumer Counseling Clinic InternNew Jersey Attorney General's Office, Consumer Fraud Prosecution Bureau Newark, NJ Jun 2012 to Aug 2012 Legal InternKings County District Attorney's Office, Domestic Violence Bureau Brooklyn, NY Mar 2012 to May 2012 Legal InternHon. Sherry Klein Heitler New York, NY Sep 2011 to Nov 2011 Judicial InternHon. Carla E. Craig Brooklyn, NY Jun 2011 to Aug 2011 Legal InternHinman, Howard, and Kattell LLP Binghamton, NY Jun 2009 to Aug 2009 Legal AssistantNew York Department of Environmental Conservation Ray Brook, NY Jun 2008 to Aug 2008 Summer Intern, Division of Permits
2010 to 2000 Lead CarpenterCarpenter Union Cranford, NJ 2006 to 2010 Journeyman (Carpenter)Roselle Police Department Roselle, NJ 2002 to 2004 Patrolman
Education:
John H. Stamler Police Academy 2002 to 2003 lawsAbraham Clark High School 1998 to 2002 industrial technology
Sprint Corporation Stratford, CT Aug 2013 to Mar 2014 Global Account Manager - IBM Alliance TeamSprint Corporation New York, NY Oct 2010 to Aug 2013 Consultant - Executive Briefing CenterTelwares Parsippany, NJ Mar 2008 to Oct 2010 Sr. Account ExecutiveSprint Corporation
Jun 2002 to Mar 2008 Convergence EngineerSprint Corporation New York, NY Nov 1998 to Jun 2002 Global Account ManagerSprint Corporation Purchase, NY 1995 to 1998 Implementation Project ManagerSprint Corporation Purchase, NY 1990 to 1995 Customer Service Specialist/Supervisor
Colorado State University - Electrical Engineering
Relationship:
Single
About:
I play with organized lightning. I generally consider my friends in the 'awesome' category. We usually have a good time hanging out and socializing, playing games, going places, and doing thin...
Bragging Rights:
Distinguished Expert in Light Rifle, Eagle Scout, OA Vigil Honor, Ham (K0PFT)
Joseph Kelly
Work:
Grooveshark - Senior Software Engineer, Head of User Interface Grooveshark Web (2009-2012) University Of Florida - Web Administrator (2005-2009)
Education:
University Of Florida - Computer Engineering Software, College of Engineering
About:
Software Engineer at Grooveshark. Currently work as the Lead User Interface Developer for Grooveshark Web, Creates Rich Advertisements for External Customers
Joseph Kelly
Work:
Dynamic Web Solutions - SEO Associate (2013) Corrigans Rug Cleaner - Rug Specialist (2011-2011) Longwood University - ID Center (2011-2012)
Education:
Longwood University - Business Marketing, John Handley High School
I am current graduate from Purdue University and I'm in the hiring process of becoming an Air Traffic Controller for the FAA. I currently work for FedEx Express at their hub in Indianapolis International Airport. I have an amazing fiance, Anna Zarse, that I am marrying December 17, 2011. I hope to use Google+ to network with current friends and new friends!
Joseph Kelly
Work:
Double Luck - Owner Discrete Wireless - Field Technician (2008-2011)
Joseph Kelly
Education:
Brigham Young University - Exercise Science, Oregon Health & Science University - Dentistry
Joseph Kelly
Work:
Kelly Law Office LLC - Attorney
About:
When you choose the Kelly Law Office in Columbus to handle your case, you will be personally represented by founding attorney Joseph Kelly. Whether your case involves family law, criminal defense or a...
Tagline:
At the Kelly Law Office in Columbus, you will find an attorney who has been handling family law, criminal defense, bankruptcy, personal injury and other legal problems for people in Ohio since 1992. We have seen the full range of challenges that can arise in these cases, and we have overcome them. We know how to get results.
News
Harried professor and dad in viral BBC video is a former Ohioan (video)
il newspaperthat her grandchildren "probably thought they were Skyping grandma!" because she and her husband, Joseph, regularly Skype with the children from their home in University Heights, Ohio. Joseph Kelly is a professor in John Carroll University's Department of Theology and Religious Studies. "
Monsignor Joseph Kelly of St. Francis of Assisi Kitchen in Scranton recalled how Boscov created a Christmas in July charitable display about six years ago at his Scranton store. It contained new packages of socks and underwear pinned to a display that shoppers could buy for $1 each, as a donation toThis is the kind of thing the man did all over the area, Joseph Kelly said, noting that Boscov put similar displays in other stores, too. He would pit one store manager against another to see who could raise the most money.The homeless and people in need served by the soup kitchen are, not really his shoppers, quite frankly. But he was so generous, Joseph Kelly said. Actually meeting him and seeing his compassion for other people really touched my heart. I was so impressed by the fact that he was so concerned aboutHe had his manager come and help me set it up so it would be like a store, Joseph Kelly said. People remark all that time that it looks like a store. Theres a reason it looks like a store. They (Boscovs) designed the racks and everything.
Date: Feb 12, 2017
Category: Business
Source: Google
Defense Suggests Bulger's FBI Informant File Was Phony
The witness, retired Boston FBI agent Joseph Kelly, was questioned about the way information provided by informants was filed by the bureau in Boston 30 years ago, a system about which he acknowledged being uncertain.
Date: Jul 30, 2013
Category: U.S.
Source: Google
Because of faulty Breathalyzer, Philly D.A. gives 1500 another chance ...
Joseph Kelly, a Port Richmond defense attorney who specializes in DUI cases and one of the first lawyers to challenge the police machines, said new-trial requests have had a positive response by the court.
Date: May 14, 2011
Category: Health
Source: Google
Phila. breath-test readings off for 1147 cases | Philadelphia Inquirer | 2011 ...
The problem was brought to the attention of the District Attorney's Office last month by Joseph Kelly, an 11-year lawyer in Port Richmond who has specialized in DUI cases and noticed the error in a calibration report.
Joseph Kelly, a briefing consultant for Sprint, told me during the event that the Echo represents a joint development effort between Sprint and Kyocera, a consumer electronics manufacturer that acquired feature phone maven Sanyo a couple of years back.