Ashok V. Joshi - Salt Lake City UT, US John J. McEvoy - Sandy UT, US Truman C. Wold - Salt Lake City UT, US Joseph J. Hartvigsen - Kaysville UT, US Daniel Earl Snyder - Indianapolis IN, US Joseph Raymond Winkle - Indianapolis IN, US James Web Kassebaum - Indianapolis IN, US
The present invention is directed to a device for releasing a fluid. The device includes a housing having an interior region, a fluid contained within the interior region, and the ability to controllably release the fluid from the housing.
Ectoparasiticidal Aqueous Suspension Formulations Of Spinosyns
William Webster Thompson - Indianapolis IN, US Joseph Raymond Winkle - Indianapolis IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K031/7042 C07H015/24
US Classification:
514 28, 424405, 536 65, 536 71
Abstract:
The invention provides a stable ectoparasiticidal aqueous suspension formulation of a spinosyn, comprising the spinosyn, or a physiologically acceptable derivative or salt thereof, milled to an average particle size of 1 to 15 microns, a surfactant in an amount effective to facilitate wetting the milled particles; a dispersant in an amount that forms a spinosyn;dispersant weight ration of from 3:1 to 1:5; and water. It also provides a method of controlling an ectoparasite infestation on a small ruminant or companion animal comprising administering an effective amount of such an aqueous suspension formulation.
Dispenser Having Piezoelectric Elements And Method Of Operation
Mick A. Trompen - Westfield IN, US Gregory A. Lyon - Indianapolis IN, US Ronald W. Lyon - Noblesville IN, US Steven D. Lubetkin - Zionsville IN, US Joseph R. Winkle - Carmel IN, US Jeffery A. Meyer - Greenfield IN, US
Assignee:
Aircom Manufacturing, Inc. - Indianapolis IN Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 9/22
US Classification:
6048901, 604131, 604304, 119665
Abstract:
A dispenser is provided. The dispenser has a reservoir for storing a liquid or solid material. The dispenser may have a piezoelectric valve or pump located in an opening of the reservoir for regulating dispensing of the material. Alternatively, the dispenser may have a piezoelectric inchworm that directly or indirectly propels the material against or out of the opening. The opening may deposit the material directly or indirectly on the surface of an animal, or under the animal's skin. The dispenser also can be attached to the surface of the animal. Alternatively, the dispenser may be placed inside the animal.
This invention is directed to the use of spinosyn or a physiologically acceptable derivative or salt thereof for improved production of fish; controlling ectoparasite infestations in aquaculture raised fish; and fish feed formulations.
Ashok Joshi - Salt Lake City UT, US John McEvoy - Sandy UT, US Truman Wold - Salt Lake City UT, US Joseph Hartvigsen - Kaysville UT, US Daniel Snyder - Indianapolis IN, US Joseph Winkle - Indianapolis IN, US James Kassebaum - Indianapolis IN, US
International Classification:
B05B001/14
US Classification:
239/590000
Abstract:
The present invention is directed to a device for releasing a fluid. The device includes a housing having an interior region, a fluid contained within the interior region, and the ability to controllably release the fluid from the housing.
Lionel Lowe - Dural, AU Joseph Winkle - Carmel IN, US
International Classification:
A61K009/22
US Classification:
424468000
Abstract:
The present invention relates to a controlled dosage release element adapted to be inserted into and retained in the rumen of a ruminant animal. The element comprises: a) one or more discrete and predetermined amounts of at least a first formulation comprising at least a first active agent, the formulation being adapted to dissolve in rumen fluids at a rate such that dissolution of each of the one or more amounts of first formulation provides a short or pulsed episode of release of the first active agent into the rumen; and b) one or more predetermined amounts of at least a second formulation adapted to dissolve at a controlled rate in rumen fluids; wherein the one or more amounts of first formulation are provided at one or more predetermined locations within the element relative to said one or more amounts of second formulation for one or more delayed releases of at least the first active agent into the rumen at predetermined times before, during, after, or any combination thereof, of a predetermined extended time period defined by said second formulation. The invention also relates to a method for delivering at least a first active agent to the rumen of a ruminant animal in a delayed manner at one or more predetermined times after administration to the animal of a composition containing the active agent, the method comprising administering to the animal a controlled dosage release element according to the invention. The first active agent will typically be for the treatment, prophylaxis or both of a diseased or infested state in a ruminant animal, or for altering the physiological status of a ruminant animal.
Dispenser Having Piezoelectric Elements And Method Of Operation
Mick Trompen - Westfield IN, US Gregory Lyon - Indianapolis IN, US Jeffery Meyer - Greenfield IN, US Steven Lubetkin - Zionsville IN, US Joseph Winkle - Carmel IN, US Ronald Lyon - Noblesville IN, US
International Classification:
A61M 37/00
US Classification:
604131000
Abstract:
A dispenser is provided. The dispenser has a reservoir for storing a liquid or solid material. The dispenser may have a piezoelectric valve or pump located in an opening of the reservoir for regulating dispensing of the material. Alternatively, the dispenser may have a piezoelectric inchworm that directly or indirectly propels the material against or out of the opening. The opening may deposit the material directly or indirectly on the surface of an animal, or under the animal's skin. The dispenser also has means for being attached to the surface of the animal. Alternatively, the dispenser may be placed inside the animal. In certain embodiments, the dispenser comprises a reservoir containing a material to be dispensed, an actuable dispensing element, and an identifying device for remotely communicating information about the dispenser. The dispenser may also include a positioning device adapted to transmit the position of the dispenser.
Mick Trompen - Westfield IN, US Gregory Lyon - Indianapolis IN, US Jeffery Meyer - Greenfield IN, US Joseph Winkle - Carmel IN, US
International Classification:
B67D 5/00
US Classification:
239044000
Abstract:
A dispenser that delivers a small but consistent and sustained amount of liquid over an extended period of time, particularly useful but not limited to dispensing pesticides when worn by cattle. The dispenser has a shell having an opening. A reservoir is disposed in the shell and holds a pesticide or other liquid. A wick is in fluid communication with the reservoir. An end of the wick is positioned adjacent the opening and has a greater capillary attraction or wicking ability than the reservoir, whereby during use of the dispenser the wick draws fluid from the reservoir and deposits it on the animal upon contact.
In the Bowl Animal Health
Co-Chief Operating Officer
Jrw Group
Principal and Owner
Elanco
Director
Eli Lilly and Company
Director
Eli Lilly and Company
R and D Leader
Education:
University of North Carolina at Chapel Hill 1978 - 1983
Doctorates, Organic Chemistry
Davidson College 1974 - 1978
Bachelors, Bachelor of Science, Chemistry
Skills:
Pharmaceutical Industry Biotechnology Fda Lifesciences Drug Development Regulatory Affairs Life Sciences Technology Transfer R&D Clinical Development Cross Functional Team Leadership Drug Discovery Product Development Gmp Clinical Trials Strategy Strategic Planning Quality System Quality Assurance Research and Development Science
Barcroft Elementary School Arlington VA 1955-1956, Glencarlyn Elementary School Arlington VA 1956-1957, Kenmore Junior High School Arlington VA 1956-1960