Joshua Thomas Simon

US Patent:

20080063681, Mar 13, 2008

Filed:

Sep 11, 2006

Appl. No.:

11/519168

Inventors:

Bruce Simon - Mountain Lakes NJ, US
Joshua Simon - Rockaway NJ, US

Assignee:

EBI, L.P. - Parsippany NJ

International Classification:

A61K 33/42
A61K 31/65
A61F 2/02

US Classification:

424423, 514153, 424602

Abstract:

A biodegradable bone replacement material for the treatment of bone defects and delivery of antibiotic compounds, particularly for treating bone infections, comprising calcium sulfate hemihydrate, calcium sulfate dihydrate, an antibiotic mixture comprising a tetracycline compound and an ansamycin compound. Preferably, the ratio of calcium sulfate hemihydrate to calcium sulfate dihydrate is from 1:1 to about 3:1. Methods for treating, repairing or augmenting an osseous defect using the bone replacement material are also provided.

US Patent:

20080255041, Oct 16, 2008

Filed:

Apr 11, 2007

Appl. No.:

11/786154

Inventors:

Bruce Simon - Mountain Lakes NJ, US
Joshua Simon - Rockaway NJ, US

Assignee:

EBI, L.P. - Parsippany NJ

International Classification:

A61K 38/16
A61P 43/00
A61K 38/10
A61K 38/06
A61K 38/07
A61K 38/08
A61K 38/03

US Classification:

514 12, 514 18, 514 17, 514 16, 514 15, 514 14, 514 13

Abstract:

Compositions and methods for treating an annulus fibrosis defect comprising an angiogenic factor and a carrier. Methods include administering the composition to the annulus fibrosis defect, where the administering can include injecting the composition. The present compositions can stimulate angiogenesis and revascularization thereby facilitating repair of the defect.