Joshua A Stein

US Patent:

20050125159, Jun 9, 2005

Filed:

Aug 6, 2002

Appl. No.:

10/213974

Inventors:

Joshua Stein - Acton MA, US
Yongwei Cao - Chesterfield MO, US

International Classification:

G06F019/00
G01N033/48
G01N033/50

US Classification:

702020000

Abstract:

The present invention is in the field of bioinformatics, particularly as it pertains to determining the associations of biological elements. More specifically, the present invention relates to the determination of associations among a set of biological elements using methods capable of generating and sorting clusters of biological elements.

US Patent:

20210052397, Feb 25, 2021

Filed:

Oct 30, 2020

Appl. No.:

17/084718

Inventors:

- Kalamazoo MI, US
Joshua Stein - Montvale NJ, US

International Classification:

A61F 2/46
A61B 17/88
A61B 17/70

Abstract:

A bone graft loading system includes a loading funnel, syringe, cannula, plunger, and loading tool. The loading funnel includes an interior passageway to receive the cannula and a syringe docking portion. The syringe may be coupled to the syringe docking portion so that it extends along a longitudinal axis that is transverse to the longitudinal axes of the cannula and the loading funnel. A user may advance bone graft from the syringe to a holding area of the loading funnel. The user may then move the loading tool through the holding area and into the interior space of the cannula to load the cannula with bone graft. This process may be repeated until the cannula is fully loaded with bone graft. The cannula and the plunger inside the cannula may then be removed from the loading funnel and coupled to an injector assembly for use in surgery.

US Patent:

20200237413, Jul 30, 2020

Filed:

Jan 22, 2020

Appl. No.:

16/749440

Inventors:

- Wilmington DE, US
Joshua Stein - Montvale NJ, US

International Classification:

A61B 17/70
A61B 90/00

Abstract:

A system for percutaneous spinal fusion may include two spaced apart blades connected together by a coupling such that the blades define a percutaneous pathway from a skin incision to an implanted pedicle fastener. The coupling may be c-shaped and may have at least one flexible tab for engaging one or more holes along the length of the blades. If one of the blades becomes disconnected from the pedicle fastener, a supplemental access device may be provided comprising a tubular body having a channel therein for receiving the other of the blades. If both of the blades become disconnected, a supplemental access device may be provided comprising a gripping member received within a locking member. The gripping member may have two legs engageable with the pedicle fastener, and the locking member may move along the gripping member to prevent the legs from disengaging the pedicle fastener.

US Patent:

20160184221, Jun 30, 2016

Filed:

Mar 9, 2016

Appl. No.:

15/064623

Inventors:

- Woonsocket RI, US
Perry ANTELMAN - Sharon MA, US
Bharat MADHAVAN - Kingston RI, US
Joshua Steven STEIN - Sharon MA, US
Elia ALTABET - Sharon MA, US

International Classification:

A61K 9/00
A61K 9/06
A61K 9/10
A61K 33/38

Abstract:

There are disclosed topical silver(II) antibiotic formulations. Other embodiments are also disclosed.

US Patent:

20140325710, Oct 30, 2014

Filed:

Jan 24, 2014

Appl. No.:

13/999189

Inventors:

- St. Louis MO, US
Joshua Stein - Acton MA, US
Steven D. Rounsley - Boylston MA, US
Jason Cotter - Camden NJ, US
Angela Ferguson - Morrisville NC, US
Li Zhou - Belmont MA, US
Karen Kindle Hartsuyker - Kirkwood MO, US
Susan Norris - University City MO, US
Barry S. Goldman - St. Louis MO, US
James F. Todd - Otterville, CA
Robert L. D'Ordine - Ballwin MO, US

International Classification:

C12N 15/82

US Classification:

800298, 4353201

Abstract:

Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for expression of mRNA complementary to at least a portion of an mRNA native to the target plant for use in gene suppression to suppress the expression of a protein.