Joshua Y Yang

US Patent:

8294132, Oct 23, 2012

Filed:

Mar 30, 2010

Appl. No.:

12/750351

Inventors:

Feng Miao - Mountain View CA, US
Joshua Yang - Palo Alto CA, US
Wei Wu - Palo Alto CA, US
Shih-Yuan Wang - Palo Alto CA, US
R. Stanley Williams - Portola Valley CA, US

Assignee:

Hewlett-Packard Development Company, L.P. - Houston TX

International Classification:

H01L 29/04
H01L 47/00
H01L 29/02

US Classification:

257 3, 257 1, 257 2

Abstract:

A graphene memristor includes a first electrode, a second electrode electrically coupled to the first electrode, an active region interspersed between the first and second electrodes, a defective graphene structure that modulates a barrier height to migration of ions through the active region, fast diffusing ions that migrate under the influence an electric field to change a state of the graphene memristor, and a source that generates the electric field.

US Patent:

20110240947, Oct 6, 2011

Filed:

Apr 5, 2010

Appl. No.:

12/754300

Inventors:

Joshua Yang - Palo Alto CA, US
Feng Miao - Mountain View CA, US
Wei Wu - Palo Alto CA, US
Shih-Yuan Wang - Palo Alto CA, US
R. Stanley Williams - Portola Valley CA, US

International Classification:

H01L 47/00

US Classification:

257 3, 257E47001, 977734

Abstract:

A graphene-based memristor includes a first electrode, a defective graphene layer adjacent the first electrode, a memristive material that includes a number of ions adjacent the defective graphene layer, a second electrode adjacent the memristive material, and a voltage source that generates an electric field between the first and the second electrodes. Under the influence of the electric field, ions in the memristive material form an ion conducting channel between the second electrode and the defective graphene layer.

US Patent:

20220333182, Oct 20, 2022

Filed:

May 6, 2022

Appl. No.:

17/738988

Inventors:

- Oakland CA, US
Tara K. Sigdel - San Francisco CA, US
Joshua Y. Yang - San Francisco CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C12Q 1/6853
C12Q 1/6827
C12Q 1/6883
G16H 10/40
C12Q 1/6813
G01N 33/53
G01N 33/68
C12Q 1/6876

Abstract:

Provided herein is the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. Provided herein are methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.

US Patent:

20230072969, Mar 9, 2023

Filed:

Aug 1, 2022

Appl. No.:

17/878736

Inventors:

- Oakland CA, US
Joshua Y. YANG - San Francisco CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 33/68
G01N 33/70
A61P 13/12

Abstract:

Disclose are methods, compositions and kits for the determination of kidney function that provide an alternative to the standard-of-cure used for eGFR calculations. Described herein are methods for quantitative measurement of ADMA and hydration markers in a urine sample, and process used to transform the input of these methods into a measure of kidney function. The methods allow ADMA and other biomarkers to be detected in urine samples from a subject using a simple and inexpensive assay that can be easily performed noninvasively and only require urine samples for the prediction of kidney function.

US Patent:

20210373035, Dec 2, 2021

Filed:

Jul 28, 2021

Appl. No.:

17/387917

Inventors:

- Oakland CA, US
Joshua Y. Yang - San Francisco CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 33/68
G01N 33/70

Abstract:

Disclose are methods, compositions and kits for the determination of kidney function that provide an alternative to the standard-of-cure used for eGFR calculations. Described herein are methods for quantitative measurement of ADMA and hydration markers in a urine sample, and process used to transform the input of these methods into a measure of kidney function. The methods allow ADMA and other biomarkers to be detected in urine samples from a subject using a simple and inexpensive assay that can be easily performed noninvasively and only require urine samples for the prediction of kidney function.

US Patent:

20210340610, Nov 4, 2021

Filed:

Jul 15, 2021

Appl. No.:

17/376919

Inventors:

- Oakland CA, US
Tara K. Sigdel - San Francisco CA, US
Joshua Y. Yang - San Francisco CA, US

International Classification:

C12Q 1/6853
C12Q 1/6827
C12Q 1/6883
G16H 10/40
C12Q 1/6813
G01N 33/53
G01N 33/68
C12Q 1/6876

Abstract:

This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.

US Patent:

20210024988, Jan 28, 2021

Filed:

Oct 7, 2020

Appl. No.:

17/065417

Inventors:

- Oakland CA, US
Tara K. Sigdel - San Francisco CA, US
Joshua Y. Yang - San Francisco CA, US

International Classification:

C12Q 1/6853
C12Q 1/6827
C12Q 1/6883
C12Q 1/6876

Abstract:

This application relates to the use of measurements of cell-free DNA, protein, and/or metabolite found in biofluid (e.g., urine) for identifying and treating organ injury. The application includes methods and compositions for monitoring, detecting, quantifying, and treating kidney injury in subjects suffering from or suspected of having an altered renal status by measuring amounts of cfDNA and one or more other markers, such as inflammation markers, apoptosis markers, protein, and DNA methylation.

US Patent:

20200032331, Jan 30, 2020

Filed:

Oct 9, 2019

Appl. No.:

16/597782

Inventors:

- Oakland CA, US
Tara K. Sigdel - San Francisco CA, US
Joshua Y. Yang - San Francisco CA, US

International Classification:

C12Q 1/6853
C12Q 1/6883
C12Q 1/6827
C12Q 1/6876

Abstract:

This present disclosure provides methods and compositions that can be used to quantify cfDNA in biofluids using a hybridization approach.