Joyce Mary Gallagher

US Patent:

20140050700, Feb 20, 2014

Filed:

Dec 13, 2012

Appl. No.:

13/713457

Inventors:

Grant Gallagher - Milltown NJ, US
Joyce Gallagher - Milltown NJ, US
Jihong Dai - Ambler PA, US
Nicholas Megjugorac - Lopatcong NJ, US
Grant E. Gallagher - Hamilton NJ, US

Assignee:

Medical Diagnostic Laboratories, LLC - Hamilton NJ

International Classification:

A61K 35/14
A61K 38/21

US Classification:

424 855, 424 9371

Abstract:

The present invention provides a method of treating Th2-associated diseases and disorders by modulating the expression or secretion of IL-4, IL-5 and IL-13 using interferon lambda (IFN-λ). For Th2-associated diseases and disorders, cells of a patient having a Th2-associated disease or disorder are treated ex vivo, with IFN-λ and returned to the patient. The present invention also provides a method of ex vivo treatment, in conjunction with co-administration of IFN-λ