Judith D Connor

US Patent:

20110091971, Apr 21, 2011

Filed:

Jun 29, 2009

Appl. No.:

12/493741

Inventors:

Janet Davis - Skillman NJ, US
Jiajian Liu - Skillman NJ, US
Gopalan Raghunathan - San Diego CA, US
Michael Joseph Hunter - San Diego CA, US
Jose Pardinas - San Diego CA, US
Judith Ann Connor - San Diego CA, US
Ronald Vernon Swanson - San Diego CA, US
Ellen Chi - San Diego CA, US

International Classification:

C12N 5/0735
C12N 5/071

US Classification:

435377

Abstract:

The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and compositions to differentiate pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage. The present invention also provides methods to generate and purify agents capable of differentiating pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage.

US Patent:

20190359705, Nov 28, 2019

Filed:

May 29, 2019

Appl. No.:

16/424907

Inventors:

- Horsham PA, US
Judith Connor - San Diego CA, US
Chichi Huang - Berwyn PA, US
Jarrat Jordan - Norristown PA, US
Jinquan Luo - Malvern PA, US
Lu Lu - Schwenksville PA, US
Christian Martinez - San Diego CA, US
Galina Obmolova - Phoenixville PA, US
Ronald Swanson - San Diego CA, US

International Classification:

C07K 16/24
A61K 38/13
A61K 45/06

Abstract:

The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

US Patent:

20190292241, Sep 26, 2019

Filed:

May 15, 2019

Appl. No.:

16/412819

Inventors:

- Horsham PA, US
Judith Ann Connor - Vista CA, US
Jennifer Furman - San Diego CA, US
Chichi Huang - Malvern PA, US
Michael J. Hunter - Santee CA, US
Serena Nelson - San Diego CA, US
Shamina M. Rangwala - Furlong PA, US
Shannon Mullican - Philadelphia PA, US
Jose Antonio Chavez - Warrington PA, US

International Classification:

C07K 14/765
C12N 15/62
C12N 15/09
C07K 14/475
C12N 15/63
C12N 15/11
C12N 15/00
C12N 5/12
C07K 14/46
A61K 38/16
C07K 14/435
A61K 38/18
C07K 14/47
C07K 14/51
A61K 38/17
A61K 38/19

Abstract:

Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.

US Patent:

20180002418, Jan 4, 2018

Filed:

Sep 18, 2017

Appl. No.:

15/707317

Inventors:

- Horsham PA, US
Judith Connor - San Diego CA, US
Chichi Huang - Spring House PA, US
Jarrat Jordan - Spring House PA, US
Jinquan Luo - Spring House PA, US
Lu Lu - San Diego CA, US
Christian Martinez - San Diego CA, US
Galina Obmolova - Phoenixville PA, US
Ronald Swanson - San Diego CA, US

Assignee:

Janssen Biotech, Inc. - Horsham PA

International Classification:

C07K 16/24

Abstract:

Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.

US Patent:

20170327560, Nov 16, 2017

Filed:

May 4, 2017

Appl. No.:

15/586463

Inventors:

- Horsham PA, US
Judith Ann Connor - Vista CA, US
Jennifer Furman - San Diego CA, US
Chichi Huang - Malvern PA, US
Michael J. Hunter - Santee PA, US
Serena Nelson - San Diego PA, US
Shamina Rangwala - Furlong PA, US
Shannon Mullican - Philadelphia PA, US
Jose Antonio Chavez - Warrington PA, US

Assignee:

Janssen Biotech, Inc. - Horsham PA

International Classification:

C07K 14/765
C07K 14/475
A61K 38/00

Abstract:

Fusion proteins containing a half-life extension protein, a linker, and a GDF15 protein are described. Also described are nucleic acids encoding the fusion proteins, recombinant cells thereof, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing metabolic diseases, disorders or conditions.

US Patent:

20150368338, Dec 24, 2015

Filed:

Jun 22, 2015

Appl. No.:

14/745939

Inventors:

- Horsham PA, US
Judith Connor - San Diego CA, US
Chichi Huang - Spring House PA, US
Jarrat Jordan - Spring House PA, US
Jinquan Luo - Spring House PA, US
Lu Lu - Spring House PA, US
Christian Martinez - San Diego CA, US
Galina Obmolova - Spring House PA, US
Ronald Swanson - San Diego CA, US

International Classification:

C07K 16/24
A61K 45/06
A61K 39/395

Abstract:

The present invention relates to antibodies that broady neutralize interferon-α and interferon-ω, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

US Patent:

20140271648, Sep 18, 2014

Filed:

Mar 13, 2014

Appl. No.:

14/208861

Inventors:

- Horsham PA, US
Judith Connor - San Diego CA, US
Chichi Huang - Spring House PA, US
Jarrat Jordan - Spring House PA, US
Jinquan Luo - Spring House PA, US
Lu Lu - San Diego CA, US
Christian Martinez - San Diego CA, US
Galina Obmolova - Spring House PA, US
Ronald Swanson - San Diego CA, US

Assignee:

Janssen Biotech, Inc. - Horsham PA

International Classification:

C07K 16/24
C07K 16/46

US Classification:

4241361, 5303879, 5303873, 4241391

Abstract:

Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.